North America Autoimmune Monoclonal Antibodies Market is expected to reach USD 11,709.7 million by 2021 from USD 7,798.3 million in 2016, growing at a CAGR of 8.47% during forecast period 2016-2021. Irregular functioning of humans’ immune system results in autoimmune disorders.
Overproduction of self-reactive immune cells (such as antibodies & T-cells) damage regular functions of /cells/tissues/organs. This lead to different autoimmune disorders such as systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, and others diseases. Typically, drugs are used as a treatment to cure autoimmune disorders. The adverse effects associated with drugs has made switched to concentrate on monoclonal antibodies.
Monoclonal antibodies have the ability to offer less toxic and more efficient therapeutic alternatives to treat autoimmune diseases. Recent years have seen the emergence of monoclonal antibodies being used to treat wide array of diseases that are related to immune response. These antibodies are mono-specific comprising of identical immune cells which are clones of a single parent cell and are directed towards a specific cellular target. Thus monoclonal antibodies due to its customizable nature can be used to treat the self-reactive immune cells not impacting the normal ones.
Growing number of patients with autoimmune diseases, increasing research and development to promote the development of monoclonal antibodies, presence of large number of biotechnology companies, and rising demand for effective therapeutics are driving the growth of autoimmune monoclonal antibodies market in North America. In addition, increasing innovations in monoclonal antibodies research, rising number of product launches, and growing number of collaborations & agreements to promote autoimmune therapies using monoclonal antibodies are further supporting the growth of autoimmune monoclonal antibodies market in North America. However, stringent regulatory pathways and lack of proper reimbursement policies are expected to limit the growth of autoimmune monoclonal antibodies market in North America.
North America Autoimmune Monoclonal Antibodies market is segmented based on source, application, and end user. Based on source, the market is further sub-segmented as Murine, Chimeric, Humanized, and Human. Among these, humanized segment is expected to command the largest share in North America Autoimmune Monoclonal Antibodies market, by source in 2016. Based on application, the market is further segmented as Systemic Lupus Erythematosus, Rheumatoid Arthritis, Multiple Sclerosis, Transplant Rejection/Graft Versus Host Disease, and Others. Of these, rheumatoid arthritis application is anticipated to command the major share in North America Autoimmune Monoclonal Antibodies market, by application in 2016. Based on end user, the market is further segmented as Hospitals/Clinics, Research Institutes, and Diagnostic Laboratories. Among these, Hospitals/Clinics segment is expected to hold the major market share in North America Autoimmune Monoclonal Antibodies market, by application in 2016.
On the basis of geographical areas, North America Autoimmune Monoclonal Antibodies market is segmented as U.S., and Canada.
The key players in Autoimmune Monoclonal Antibodies market include, GlaxoSmithKline plc (U.K.), AstraZeneca plc (U.K.), F. Hoffmann-La Roche Ltd. (Switzerland), Bristol-Myers Squibb (U.S.), Johnson & Johnson (U.S.), Innovent Biologics, Inc. (China), Takeda Pharmaceutical Company Ltd. (Japan), Amgen Inc. (U.S.), Biogen Inc.(U.S.), and UCB Company (Belgium).
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