Sample preparation kits are anticipated to hold the largest market share by 2025
Among the different product type segments of the global DNA and RNA sample preparation market, the Kits segment dominated the global DNA and RNA sample preparation market in revenue terms in 2016 and is projected to continue to do so throughout the forecast period. The Kits segment – which consists of two sub-segments namely DNA sample preparation kits and RNA sample preparation kits – is estimated to be valued at more than US$ 800 Mn (close to 60% share of the total market) in 2017 in terms of revenue, expanding at a CAGR of 5.5% over the forecast period. The segment is expected to represent absolute $ opportunity of more than US$ 40 Mn in 2018 over 2017, also creating an incremental $ opportunity close to US$ 440 Mn between 2017 and 2025. Revenue from the Kits product type segment is expected to increase 1.5X between 2017 and 2025. The advantages of kits over other sample preparation products include minimal DNA loss, recovery of high molecular weight DNA, improved reliability and reproducibility.
High-cost products and challenges in vendor selection are likely to hamper the growth of the Kits segment over the period of assessment
Increasingly complex requirements from researchers in the life sciences domain have led to a development of novel products that are expensive. Due to uncertainties in the results expected from complex experiments, several users do not prefer to invest in such expensive products, especially for research groups with limited budgets and funding. Furthermore, custom research products and services are usually several-fold more expensive than products listed on the catalogs of most major suppliers of research products. These factors are creating a negative impact on the growth of the Kits segment.
The major challenge whenever isolating, manipulating, or analyzing RNA is the presence of RNases. These are extremely stable and very active nucleases capable of degrading RNA. For example, bovine pancreatic ribonuclease A is one of the hardiest enzymes in common usage; one isolation method boils a cellular extract until all proteins other than RNase A are denatured. Therefore, an RNase-free work area is essential when isolating RNA. Besides, challenges of nucleic acid sample preparation working with RNA provides very different challenges from working with DNA. Owing to this, the growth of the RNA sub-segment of the Kits product type segment is likely to be hampered during the forecast period.
Process related challenges is another factor that is expected to restrain the growth of the Kits segment. Contamination of the DNA-RNA samples after the sample preparation may interfere with the analysis. Besides, the extremely small sample size that is obtained after the sample preparation is found to be very difficult to analyze. Scarce RNA transcripts and viral nucleic acids in biological fluids are difficult to detect. Degradation of samples starts as soon as the sample is collected, particularly RNA samples. All these factors act as impediments in the revenue growth of the Kits segment..
Kits is the dominant and attractive product type segment across key regional DNA and RNA sample preparation markets
The Kits product type segment dominated the North America DNA and RNA sample preparation market in revenue terms in 2016 and is projected to continue to do so throughout the forecast period. The Kits segment is the most attractive segment, recording an attractiveness index of 5.0 over the forecast period in the North America DNA and RNA sample preparation market. The Latin America region is developing its healthcare infrastructure and ongoing studies in clinical testing and diagnostic testing are likely to contribute largely to the growth of the Kits product type segment of the DNA and RNA sample preparation market in Latin America.
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