Immune thrombocytopenic purpura (ITP), also known as idiopathic thrombocytopenic purpura, is a blood disorder characterised by weakened functioning of clotting of blood. People with the disease have a tendency to bleed or bruise as a result of a low number platelets or thrombocytes which results from the self-destruction of platelets by body’s own immune system. Some of the risk factors for the disease include viral infection, use of certain drugs during pregnancy or other immune disorder. ITP is more common in women and children. According to the National Organization for Rare Disorders, the prevalence of the disease is 9.5 cases per 100,000 people.
Significant growth is expected in the therapeutics pipeline for ITP in the near future primarily driven by the rising demand for combination therapies due to their superior safety and efficacy profile as compared with other treatments, rising prevalence of viral diseases that are a major risk factor for ITP, favourable government regulations such as the Orphan Drug Act in the U.S. resulting in increasing research and development investments for new drug candidates for ITP.
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Some of the major players involved in the development of drugs for ITP include 3SBio Inc., AkaRx Inc., arGEN-X BV, Jiangsu Hengrui Medicine Co., Ltd., UCB Biopharma S.P.R.L., Kyowa Hakko Kirin China Pharmaceutical Co. Limited, Shionogi Inc., Protalex, Inc., Momenta Pharmaceuticals, Inc., Amgen Inc., Shire plc, Rigel Pharmaceuticals, Inc., Genosco, Inc.
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