Microbial fermentation is an industrial process of manufacturing a wide number of metabolites and biomaterials by using microbes in a controlled culture environment. Technically, it is the anaerobic conversion of sugar to carbon dioxide and alcohol by microorganisms. This can be performed in a batch, fed-batch or continuous mode depending upon the product type. Final product in the fermentation process is dependent on the choice of organism, medium used, agitation, pH, temperature, dissolved oxygen and various other factors. The recent advances in biotechnology and engineering helps in maximizing the yield and reduction of overall cost.
Microbial fermentation technology is the favorable biological process because of simplicity, specificity, lower cost and versatility of reaction. Utilization of fermentation technology in vast applications diversify its market.
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Microbial Fermentation Technology Market: Drivers & Restraints
Increasing utilization of medically important products such as biosimilars, recombinant proteins, antibiotics, solvents such as ethanol & alcohol beverages, fermented food products as cheese, bread, buttermilk etc. are driving the microbial fermentation technology market. Increasing biofuels production and blending with the normal fuels have also increased the market of microbial fermentation technology. Rise in the R&D activities by corporate as well as institutional participants in search of novel applications also fuels the market. Several challenges in scaling up the bioprocess for large scale commercial applications are limiting the market to expand. In addition to this, high expense in the specifically designed microbes for protein production also limits the growth.
The market is trending with the new generation fermentation products such as therapeutic recombinant proteins, anti-viral products and DNA & monoclonal antibodies. There are various newer drug substances discovered by the use of recombinant technology such as single-domain antibodies, peptibodies, or antibody fragments requires the use of microbial fermentation technology. With the rise in number of contract research organizations over the globe, manufacturing capabilities have increased manifold. Companies are thinking of differentiating strategies for innovation in the manufacturing and scaling process as to increase the production and reducing the costs. Mergers and collaborations between manufacturing industries, CROs and academic institutes are also enlarging the market.
A geographic condition regarding the Microbial Fermentation Technology Market, it has been segmented into five key regions: North America, Latin America, Europe, Asia-Pacific and the Middle East & Africa. Large number of established research organizations, manufacturing facilities for bio-fuels and brewery are making North America an established market player in the use of microbial fermentation technology. This is followed by Europe mostly because of the usage of this technology in brewery industry. Latin America is also in the race because of huge establishment of bio-fuel industry. Asia-Pacific market is the emerging market for the microbial fermentation technology due to the government initiatives in the bio-fuel production and the establishment of more bio-pharmaceuticals as well as food & beverage industries in the region.
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There is diverse market in the use of microbial fermentation technology. Some of the global players involved in the manufacturing of various products includes Biocon, Danone Ltd., Lonza, United Breweries Ltd., Carlsberg, Amyris, DuPont, Novozymes, TerraVia Holdings, Inc. and many others.
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