This report provides an overview of the women’s health pipeline landscape. The report provides comprehensive information on the therapeutics under development and key players involved in therapeutic development for female infertility, polycystic ovarian syndrome and endometriosis, and also features dormant and discontinued projects.
The three key disorders covered in this report are largely driven by dysfunction of the endocrine system, but have a broad range of effects. Infertility is defined as the inability to get pregnant after a year of unprotected intercourse. Female infertility can be also be caused by a number of factors, which include damage to fallopian tubes, hormonal causes, cervical causes, uterine causes, unexplained infertility. Polycystic ovary syndrome (PCOS) is a common hormonal disorder among women of reproductive age. Symptoms include menstrual abnormality, acne, thinning hair on the scalp, weight gain, excess androgen and polycystic ovaries. Finally, endometriosis is an often painful disorder in which tissue that normally lines the inside of uterus (the endometrium) grows outside the uterus (endometrial implant). Symptoms include pelvic pain, menstrual cramps, inflammation, infertility and abnormal bleeding.
The size of these pipelines ranges from 12 in PCOS to 87 in female infertility. The most common types of therapy being developed in these diseases act on hormone receptors, reflecting the hormone-driven pathophysiology of this disease area. However, particularly in polycystic ovarian syndrome, a broader range of molecular targets, such as intracellular protein kinases, chemokine receptors and other cell signaling components are also targeted.
– Which companies are the most active within the pipeline for women’s health therapeutics?
– Which pharmaceutical approaches are the most prominent at each stage of the pipeline and within each indication?
– To what extent do universities and institutions play a role within this pipeline, compared to pharmaceutical companies?
– What are the most important R&D milestones and data publications to have happened in the field of women’s health therapeutics?
Reasons to buy
– Understand the overall pipeline, with an at-a-glance overview of all products in therapeutic development for each indication
– Assess the products in development in granular detail, with an up-to-date overview of each individual pipeline program in each indication, and a comprehensive picture of recent updates and milestones for each
– Analyze the companies, institutions and universities currently operating in the pipeline, and the products being fielded by each of these
– Understand the composition of the pipeline in terms of molecule type, molecular target, mechanism of action and route of administration
Table of Content: Key Points
Executive Summary 3
Table of Contents 4
List of Tables 5
List of Figures 8
Women’s Health Cluster Report Coverage 9
Women Infertility – Overview 9
Polycystic Ovarian Syndrome – Overview 9
Endometriosis – Overview 9
Therapeutics Development 10
Women Infertility 10
Polycystic Ovarian Syndrome 18
Therapeutics Assessment 29
Women Infertility 29
Polycystic Ovarian Syndrome 37
Companies Involved in Therapeutics Development 53
Women Infertility 53
Polycystic Ovarian Syndrome 74
Dormant Projects 89
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