Insomnia therapeutic pipeline analysis is expected to experience vast growth in future, with the increasing level of stress being the major contributor for the rising prevalence of the disease. Some of the other major factors driving the pipeline for insomnia include lifestyle diseases, smoking, alcohol and tobacco consumption and increasing health awareness. According to the data by American Academy of Sleep Medicine, every year eight million people suffer from insomnia in the U.S. It is believed that the disease is more commonly found in females as compared to males.
Insomnia is an intricate condition which involves difficulty in sleeping. It is categorized into two types based on its duration, acute insomnia and chronic insomnia. Acute insomnia is short-termed and frequently happens because of the increasing stress in. This type of insomnia does not require treatment and resolves itself. Chronic insomnia is a severe problem when a person is unable to sleep for at least three nights per week and this lasts for more than three months. Chronic insomnia is caused by several factors including changes in environment, work stress, certain medications and other clinical diseases. Sometimes, chronic insomnia is also linked with other psychiatric problems, which makes it difficult to diagnose. Some of the other causes of insomnia include asthma, arthritis, hyperthyroidism, parkinson’s disease, lower back pain, chronic pain, gastrointestinal problems and nasal allergies. Some medications such as medicines prescribed for high blood pressure, asthma, birth control, heart disease and nasal allergies, can also cause insomnia. Common symptoms of insomnia include tiredness, mood swings, change in behaviour, problems in relationships and others. Insomnia is diagnosed by physical examination and analysing the symptoms in an individual. Insomnia is treated by using several approaches which includes cognitive behavioral therapy, relaxation training and medication treatment. Some marketed medicines for insomnia includes non-benzodiazepine hypnotics, melatonin receptor agonists and benzodiazepine hypnotics.
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Some of the companies having a pipeline of insomnia therapeutics include Eisai Co., Ltd., Actelion Pharmaceuticals Ltd., Ache Laboratorios Farmaceuticos S.A., Merck Sharp & Dohme Corp., Evotec AG, Bristol-Myers Squibb Company, Johnson & Johnson, Alexza Pharmaceuticals, Inc., Reviva Pharmaceuticals Inc., Shionogi & Co., Ltd., Novartis AG, Takeda Pharmaceutical Company Limited, Neurim Pharmaceuticals Ltd., Heptares Therapeutics Limited, Intra-Cellular Therapies, Inc.
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