The fallopian tube cancer therapeutics pipeline is a major focus for the pharmaceutical companies and researchers since it is one of the most debilitating women’s disease. The invention of novel drug delivery and the targeted therapy is expected to drive the pipeline growth for fallopian tube cancer. Increasing awareness regarding cancer treatment, advancement in technologies, high demand for safe and effective medications and high prevalence of cancer are driving the growth of fallopian tube cancer therapeutics pipeline.
The fallopian tube is a part of female reproductive system and are a pair of thin tubes that transport ova from women’s ovaries to the uterus where they are either fertilized by male sperm or discarded during menstruation. In fallopian tube cancer, an abnormal growth of malignant cells occurs in one or both of a woman’s fallopian tubes. The most common fallopian tube cancers are papillary serous adenocarcinomas. The papillary serous adenocarcinomas are an abnormal growth of the fallopian tube cells. Fallopian tube cancer mainly affects women from ages 18-88, and is most commonly found in women aged between 40 and 65 years old.
The pipeline of fallopian tube cancer therapeutics includes, but is not limited to atezolizumab (MPDL 3280A), Ribociclib and Binimetinib. Atezolizumab is being developed by F. Hoffmann-La Roche AG. It is a monoclonal antibody targeting programmed cell death-1 ligand 1 (PD-L1 or CD274 antigen). PD-L1 plays an important role in suppressing the immune system triggered by disease.
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Some of the companies having a pipeline of fallopian tube cancer therapeutics include Amgen Inc., AstraZeneca plc, Bayer AG, Boehringer Ingelheim GmbH,
Bristol-Myers Squibb, Celgene Corporation, Eli Lilly and Company, GlaxoSmithKline plc, Incyte Corporation and F. Hoffmann-La Roche AG.
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