Acute kidney injury (AKI) or acute renal failure is a common complication in critically ill patients and is often associated with mortality and morbidity. Renal replacement therapies have witnessed significant technological advancements in the last two decades. A steady and positive evolution in the areas of hemodialysis (diffusion-based removal of solute) and hemofiltration (convection-based removal of water and solute), and consequently in the treatment of AKI is approached, and the introduction of new devices and techniques have made more efficient renal replacement therapies possible.
Continuous renal replacement therapy (CRRT) is a popular choice for the treatment of ICU patients with AKI, especially for hemodynamically unstable cases. CRRT involves solute removal from blood by either hemofiltration or hemodialysis, or a combination of both. CRRT is carried out for about 24 hours in an ICU, making it quite different from conventional renal replacement therapies that involve intermittent hemodialysis lasting from four to six hours or even less.
One of the major advantages of CRRT is the slower rate of removal of solute or fluid per unit time. Hence, CRRT is better suited than conventional therapies involving intermittent hydrolysis as many of the complications occurring are related to the rapid rate of removal or loss of solute and fluid. These clinical advantages of CRRT over other renal replacement therapies and the potential for higher survival rates (realized by several trials and surveys) have led to an increased demand for CRRTs in the past few years. Nephrologists are increasingly prescribing CRRT owing to its short- and long-term benefits and the adoption among patients is rising at a steady pace globally.
A complete analysis of the market’s regulatory scenario and competitive landscape has also been provided in the report, with detailed data regarding major rules, regulations and policies, and key vendors operating in the market.
Rising global geriatric population, continuous increase in the number of ICU patients, growing preference of health care practitioners to the modality over conventional hemodialysis methods owing to the clinical benefits of CRRT, and technological advancements in the field of CRRT systems are the major factors driving the global CRRT market.
High cost of CRRT systems, dearth of trained staff for handling CRRT systems, stringent regulations in the developed regions, and unfavorable medical reimbursement policies in developing countries are holding back the market. The factors of high cost of these systems as well as the overall procedure involving CRRT systems and unfavorable medical reimbursement policies are especially affecting the large-scale adoption of CRRT systems in developing and under-developed countries.
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Nevertheless, continuous rise in investments aimed at improving health care infrastructure and rising disposable incomes in major developing markets such as China, India, and Brazil are likely to open favorable growth avenues for the global CRRT market. The rising geriatric population in these countries has also led to an increase in demand for CRRT systems.
The report provides details such as business profiles, revenues, SWOT analysis, Porter’s Five Forces Analysis, and recent technologic developments pertaining to the major companies in the global CRRT market. These include Baxter International, Bellco S.r.l., NxStage Medical, Inc., B. Braun Melsungen AG, and Asahi Kasei Medical Co., Ltd. The market is being defined by collaborations and partnerships. Companies strive to commercialize their CRRT portfolios to gain a larger share of the market.
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