Whole genome amplification was being developed in 1992. This technique is used for amplifying the entire genome from very small amount of genomic DNA; this helps in increasing the quantity of limited DNA samples, and so any gene can be studied in the organism by preserving the limited sample. Whole genome amplification is a useful technique and has various applications such as forensics and genetic disease research, apart from this, there are new techniques such as array comparative genomic hybridization (CGH) and next-generation sequencing, where a few DNA quantities but analyses is required. There are also various whole genome amplification techniques that are developed wherein they differ both in the protocol as well as replication accuracy. Whole genome amplification techniques utilize the principals of polymerase chain reaction (PCR) so as to copy enzymatically the DNA contained within a sample. Moreover, the amplification of the whole genome is non-specific and theoretically provides an increased amount in the copy number of all genomic sequences. The application of whole genome amplification is mostly in research studies where small DNA samples are regularly encountered. These applications comprise creation of probes from microdissected or flow-sorted chromosomes, preimplantation genetic diagnosis, and study of ancient DNA samples.
Whole Genome Amplification Market: Drivers and Restraints
The global whole genome amplification market is driven by the rising incidence of genetic disorders owing to rising population. According to CDC (Centers for Disease Control and Prevention) and the study conducted by National Center for Health Statistics the estimated prevalence of autism spectrum disorder (ASD) is 22.4 per 1,000 children in the age group of 3 to 17 years in 2013. In addition to this the whole genome amplification kits are easier and faster, apart from this only small amount of DNA is required for multiple samples. Growing awareness of applications of whole genome amplification techniques is expected to provide high growth opportunities for the whole genome amplification products such as kits manufacturers over the forecast period. Moreover, technological developments and emphasis on specificity and sensitivity of the kits is expected to provide significant growth opportunities for whole genome amplification product manufacturers. However, the whole genome amplification makes it difficult to derive accurate genomic information from single-cell genomes is expected to hamper market growth over the forecast period.
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Whole Genome Amplification Market: Segmentation
The global whole genome amplification market are segmented into product type and end user
Segmentation based on product type
- Single Cell WGA Kit
- WGA and ChIP DNA
- WGA Reamplification Kit
- Complete WGA Kit
- DNA Amplification Kit
Segmentation based on application
- Medical Applications
- Genetic disorders
- Food safety
- Agriculture research
Segmentation based on end user
- Research Centers
- Academic Institutes
- Pharmaceutical and Biotechnology Companies
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Whole Genome Amplification Market: Overview
Globally the whole genome amplification market is expected to witness robust growth over the forecast period owing to forensics labs trying to genotype five single nucleotide polymorphisms (SNP), and researchers collecting DNA from a buccal swab that only contains a few cells. The procedure is fast–six hours from start to finish are expected to gain traction over the forecast period, moreover increasing distribution network of manufacturers is expected to create high growth opportunities for the stakeholders of whole genome amplification market.
Whole Genome Amplification Market: Region – Wise Outlook
Regionally, whole genome amplification market is segmented into seven key regions, North America, Latin America, Western Europe, Eastern Europe, APEJ (Asia-Pacific excluding Japan), Japan and the Middle East and Africa (MEA)
North America is expected to dominate the whole genome amplification market over the forecast period. Western Europe is expected to follow next after North America owing to increasing awareness of whole genome amplification in this region. Increasing application of whole genome amplification in forensic and genetic disorders in Japan is expected to boost demand for whole genome amplification in this country. APEJ is expected to follow next regarding revenue growth owing to technological developments and the introduction of new products from the local players. Latin America and MEA regions are also expected to witness significant growth in whole genome amplification market over the forecast period.
Whole Genome Amplification Market: Key Players
Some key players in peripheral embolization market are Sigma-Aldrich Co. LLC., QIAGEN, Thermo Fisher Scientific Inc., New England Biolabs., General Electric Company, LGC Limited, Genetica DNA Laboratories – a LabCorp brand, NuGEN Technologies, Inc., Illumina, Inc. and others. The companies are focused on understanding the fundamental epigenomic and genomic regulatory pathways underlying normal cell growth and tissue differentiation.