Animal serum has always been added to culture media as a source of the nutrient. But now it has become an old age practice due to the various disadvantages of serum containing media such as batch to batch variability, the presence of undefined components and risk of contamination. Use of serum-free media has increased significantly over the past few years. Serum-free media are cultural media that do not contain any type of animal serum but it may contain serum substitute. Serum-free media offer better batch to batch consistency and has the lower amount of undefined components. These media can be used to grow the specific type of cells. Serum-free media has the lower level of protein than the serum incorporated media which simplify the purification process and increase the end-yield
Over the last few years, the trend of customized medication to treat chronic and genetic disorders is increasing, and due to this, the market of cell culture media is also expected to increase. Serum containing media has various disadvantages, and this situation can be tackled using serum-free media due to these factors serum-free media market is expected to grow significantly. Serum-free media are highly specific and free of any type of contamination. Serum-free media market growth can be restricted by factors such as slow cell proliferation, need for the development of different media for different cell line which is a time-consuming process.
The global serum-free media market can be segmented on the basis of cell type, product type, end user, and geography.
Serum-free media market is expected to show significant over the forecast period. Serum-free media are being considered over media incorporating serum. Serum-free media are specific to the cells which are to be cultured and also they are free of any type of contamination. Hybridoma culture is expected to be highest revenue generating segment as it is used for the production of monoclonal antibodies which are used for targeted therapy. Stem cell segment is also expected to show significant growth as cases of the organ transplant are increasing, and stem cell can be differentiated to specialized tissues. Customized media segment is projected to have exponential growth over the forecast period as these media can be change according to the need. Biopharmaceutical market is expected to be fastest growing serum-free media segment as these companies are focusing on the development of targeted drug therapy for various genetic and chronic disorders.
Geographically, global serum-free media market can be segmented into North America, Europe, Latin America, Asia-Pacific and Middle East & Africa. North America market followed by Europe is expected to be most attractive and highest revenue generating serum-free media market due to technological advancement and presence of some of the biggest biopharmaceutical market players. But Asia-Pacific region is anticipated to be fastest growing serum-free media market attribute to the factors like low manufacturing cost, favorable regulatory guideline, increasing demand for the vaccines and focus of the global players on this region.
Some of the market participants in the global serum-free media market are ThermoFisher Scientific, Athena Environmental Sciences, Inc., Pan Biotech UK Ltd., Bichrom, Irvine Scientific, Cellular Technology Ltd., Biological Industries, Sigma-Aldrich Co. LLC, CellGenix GmbH and HiMedia Laboratories. These companies are focusing on the development of more consistence serum-free media. They are also working on the development of media which provide better cell growth, increase productivity and reduce development period.
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