Adjuvants have been used for decades to improve the immune response to vaccine antigens. They improve the body’s immune response and often allow for smaller amounts of an inactivated virus or bacteria to be used in a vaccine. However, more than one adjuvant may be present in the final vaccine product. Aluminium salts, such as aluminium hydroxide, aluminium phosphate and aluminium potassium sulfate have been used safely in vaccines for more than 70 years.
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The demand for this market is expected to increase as adjuvants will be required to enhance and extend immune responses while reducing the amount of antigen necessary in each dose. The limited immunogenicity of new and novel vaccine antigens has increased the importance of adjuvant research in vaccine development. There is a need for the development of safe and non-toxic adjuvants. Vaccines containing novel adjuvant formulations are increasingly reaching advanced development and licensing stages, providing new tools to fill previously unmet clinical needs. However, many adjuvants fail during product development owing to factors such as manufacturability, stability, lack of effectiveness, unacceptable levels of tolerability and safety concerns.
The vaccine adjuvants market can be segmented by the type of adjuvant (mineral based adjuvants, tensioactive adjuvants, adjuvant emulsions, bacteria derived adjuvants, liposome adjuvants, carbohydrate adjuvants, organic adjuvants, cytokines, virus like particles, TLR-based adjuvants and others), by mechanism of action (active immunostimulants, carriers, vehicle adjuvants) and by geography (North America, Europe, APAC and the Rest of the World).
Competitive Intelligence analysis in the form of mergers & acquisition activity, collaborations, agreements, new product launches along with the profiles of major players including InvivoGen, Sigma Aldrich, SEPPIC, OZ Biosciences, Novavax, Adjuvatis, VaxLiant and Adjuvance Technologies have been included in the report.
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