Oligonucleotide synthesis refers to the process of synthetically producing nucleic acid biomolecules with definite sequences. The process holds immense promise for a number of research and development activities across the life sciences industry, including medical diagnosis, drug manufacture, and several applications in the food and agriculture industry.
This report on the global oligonucleotide synthesis market presents a thorough assessment of the present growth dynamics of the market and its key elements. The report includes verifiable projections pertaining to the future growth prospects of the market and includes qualitative and quantitative details pertaining to historical data, growth drivers, restraints, trends, and opportunities. The report also includes detailed insights into the regulatory scenario at regional and global levels, and analyzes the impact of several policies, plans, rules, and regulations on several decisions and developments in the global oligonucleotide market.
The report segments the global oligonucleotide synthesis market on the basis of criteria such as product, end-user, application, and geography.
On the basis of product, the market is broadly classified into probe, reagent, primer, equipment, and synthesized oligonucleotide. Of these, the segment of synthesized oligonucleotides expected to register growth at the most promising pace over the report’s forecast period, chiefly owing to a vast rise in its applications in the fields of research, therapeutics, and diagnostics. The rising demand for custom oligonucleotides is also expected to boost the growth prospects of this product segment.
On the basis of end-users, the market is further segmented into diagnostic laboratory, academic research institutes, and pharmaceutical and biotechnology companies. Of these, the market is expected to witness an increased level of demand from the diagnostic laboratories sector over the forecast period, chiefly owing to the adoption of advanced technologies such as real time polymerase chain reaction, DNA microarrays, and polymerase chain reaction for a number of operations in diagnostic labs.
Some of the key factors driving the global oligonucleotide synthesis market are the rising set of applications of oligos in synthetic biology and molecular diagnostics, a vast rise in R&D spending in the fields of pharmaceuticals and biotechnology, and rising prominence of RNA-interference oligonucleotides in therapeutics and diagnostics. Several governments are also actively investing funds with the view of ramping up the capacity of oligonucleotides synthesis. The U.S. National Institutes of Health (NIH), for instance, invests nearly US$1.5 bn every year to encourage R&D activities in oligonucleotide-based applications, including, but not limited to manual manipulation of DNA.
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From a geographical perspective, the global oligonucleotide synthesis market has been examined for Asia Pacific, Europe, North America, and Rest of the World (RoW). Of these, the Asia Pacific market has emerged as one of the most promising markets for oligonucleotide synthesis, chiefly owing to a significant rise in the demand for synthesized oligos, the vast rise in R&D activities in life sciences, and increased funding for R&D activities in the region. An increasing number of leading companies in the global oligonucleotide synthesis market are entering the market via manufacturing units to exploit the vast opportunities that the region offers.
The market has witnessed a significant rise in the level of competition owing to the entry of a large number of new vendors. The increased number of companies in the market has led to intense price pressures, compelling many leading vendors to strategically cut down certain service/product arms and focus on a niche sector. Qiagen’s recent decision to trade off its nucleic acid synthesis unit and retain the high growth and high margin RNAi segment is an instance.
Some of the key companies operating in the global oligonucleotide synthesis market are BioAutomation Corporation, TriLink Biotechnologies, Inc., Agilent Technologies, Inc., Eurofins Genomics, GE Healthcare, Thermo Fisher Scientific, Inc., Link Technologies, Ltd., Integrated DNA Technologies, Inc., Nitto Denko Avecia, Inc., Glen Research, Eurogentec, BioSearch Technologies, Inc., GenScript USA Inc., Gene Link, Inc., Sigma-Aldrich Co. LLC, GeneDesign, Inc., and Qiagen.
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