3D cell culture is an artificially-created environment in which biological cells are permitted to grow or interact with their surroundings in all three dimensions. It provides an ideal environment for cell culture analytical studies, which involve assessment of multi-stage disease models with the help of cellular modeling. Cells growing on 2D substrates lack extracellular components and do not represent true in-vivo cell environment and cell-matrix and cell-cell interactions necessary for proliferation, differentiation, and cell-based functions. 3D cell culture methods are much preferred as compared to 2D models since they provide a matrix support which encourages cells to organize into structures more indicative of the in-vivo environment.
Increasing research activities, along with rising number of organizations investing in 3D cell culture development is anticipated to fuel the market. Moreover, the use of animals in research and testing of pharmaceutical industry is common since decades. 3D cell culture can potentially replace this practice used for research and testing. Pharma companies, biotechnology entities, research institutes, and laboratories are increasingly adopting 3D cell culture technique for better results. However medium and small sized pharmaceutical and laboratory players face financial challenge, as the initial investment associated with implementation of 3D cell culture is very expensive. Also, products of 3D cell culture technique usually lack consistency, which is another reason that is detaining 3D cell culture demand in the market. Lack of experienced and skilled professionals, budget constraint of small and medium sized laboratories, lack of consistency in 3D cell culture products, stringent process controls for advanced handling capabilities, ethical concern over use of animal sources issues hamper the growth of 3D cell culture market.
Regionally, the market is segmented into North America, Europe, Asia Pacific, Latin America and Middle East and Africa. Europe and North America is likely to dominate the 3D cell culture market since there is presence of several organizations operating in these region. Additionally, there are substantial R&D projects carried out in institutes resulting its high demand, affecting the revenue growth significantly. Followed is Asia Pacific which is expected to witness high growth, due to factors like tissue engineering projects in the developing economies and rise in number of research grants for drug development in this region. Moreover, positive R&D outcomes encouraging the incorporation of 3D cell cultures is expected to impact this sector with potential opportunities for growth.
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Some of the players in the 3D cell culture market are 3D Biotek LLC, 3D Biomatrix, Inc., Becton, Dickinson and Company, Corning Inc., Global Cell Solutions, Inc., InSphero AG, Lonza Group AG, Nanofiber Solutions LLC, Reinnervate Limited, Sigma-Aldrich Corp, Tecan Trading AG, Thermo Fisher Scientific, and VWR International LLC. These companies are involved in collaborations and co-marketing agreements for enhancement of product portfolio in the 3D cell culture market.
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