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SkinGun Investigational Therapy for Burns Uses Patients’ Own Stem Cells for Healing

February 2nd, 2017 Conn Hastings Genetics, Plastic Surgery, Surgery


RenovaCareRenovaCare
, a company based in New York City, is seeking FDA approval for the SkinGun, a device to treat burns using a patient’s own stem cells. Significant portions of skin can be destroyed in burn injuries, meaning that regenerative therapy is required to restore or replace the injured tissue. Current treatments for burns involve skin grafting, where healthy skin is removed from the patient and then cultured in a laboratory, sometimes for several weeks, to grow larger sheets of cells. This delay in treatment can sometimes mean that the patient dies or develops complications such as infections.

SkinGunThe SkinGun has been developed with the aim of providing a rapid treatment for burns. The developers say that compared with skin grafting, a much smaller healthy skin sample can be converted into a regenerative treatment for an equivalent sized burn injury within just 2 hours. The treatment involves converting the harvested healthy skin into a solution containing the patient’s own regenerative stem cells, which is then sprayed onto the wound using the SkinGun device.

RenovaCare have reported that in their preliminary investigations, the device shows potential for the effective treatment of second degree burns. In some patients, the signs of skin healing have become apparent in as little as four days following treatment. So far, SkinGun has been used in a small number of burn patients as an investigational therapy.

The preliminary data point to the potential for reduced recovery times and greater levels of restoration of burnt tissue. However, the device will need to receive FDA approval before it becomes clinically available in the U.S. and clinical trials are needed to fully determine its efficacy and safety.

Link: RenovaCare technology page…

Conn Hastings

Conn Hastings received a PhD from the Royal College of Surgeons in Ireland for his work in drug delivery, investigating the potential of injectable hydrogels to deliver cells, drugs and nanoparticles in the treatment of cancer and cardiovascular diseases. After achieving his PhD and completing a year of postdoctoral research, Conn pursued a career in academic publishing, before becoming a full-time science writer and editor, combining his experience within the biomedical sciences with his passion for written communication.

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