Pharmaceutical excipients are substances other than pharmacologically active drug components, which are included in the drug manufacturing process or contained in a finished pharmaceutical product dosage form. They facilitate formulation design and perform a range of functions such as increasing lubricity, enhancing flowability and improving compressibility, among other characteristics. The global market for pharmaceutical excipients has been segmented based on the source of origin or chemistry type as per U.S. pharmacopeia, i.e. plant-based, animal-based, mineral-based and synthetically derived excipients. The market has also been segmented by application type and functionality of various excipients, and by regions.
The global pharmaceutical excipients market is estimated to be valued at US$ 7,415.2 Mn by 2021 end, with various markets registering significant CAGRs during the forecast period.
The growth of the global pharmaceutical excipients market is mainly driven by increasing demand for drugs that can be consumed orally. Ease of consumption and associated patient comfort has been pushing big drug makers to develop sustained-release dosage formulations. This also contributes to extended shelf life of oral drugs, which adds to higher revenue prospects. However, non-availability of harmonized quality standards for gradation of excipients and their safety evaluation standards are some factors expected to restrain the growth of the market over the forecast period.
International regulatory benchmarking for uniform good manufacturing and distribution practices for excipients, spanning regions, is set to define the market landscape of the excipient industry over the forecast period. This is expected to be accompanied by standardized documentation, and approval and pharmacovigilance activities related to these inactive ingredients.
Based on chemistry type, the market has been segmented into plant-based, animal-based, mineral-based, and synthetically derived. Globally, naturally derived excipients are witnessing increased demand due to lesser side effects, such as flatulence, skin rashes, etc. and improved composition quality. In terms of value, the plant-based excipient is estimated to account for close to one-third of the global market share by 2021 end. The segment is expected to gain market attractiveness throughout the forecast period. The principle plant-based excipients expected to witness increased demand are microcrystalline cellulose (MCC), starch, and starch-derivatives. They would find primary application in oral formulations.
Based on application, the market has been segmented into oral, topical, parenteral formulations, and others. Others segment includes less frequently used drug delivery methods such as suppositories, intra-muscular, transdermal, ophthalmic, etc. Lack of highly developed controlled manufacturing facilities and fear of anti-microbial contamination is expected to deter the development of excipients such as solvents and co-solvents in certain regions over the forecast period.
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Based on functionality, the global excipient market has been segmented into binders, diluents, glidents, disintegrants, and others (solvents, co-solvents, anti-microbial agents, humectants, colorants, sweeteners, etc.). The binders functionality segment, consisting of binders, fillers, and coating agents are primarily used in oral solid dosage formulations and is expected to account for close to 50% of the total excipient market by value over the forecast period. The segment is expected to be valued at US$ 3,523.8 Mn by 2021 end, registering a significant CAGR over the forecast period.
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The global pharmaceutical excipients market has been segmented into five major regions namely North America, Latin America, Europe, Asia-Pacific, and the Middle East & Africa. In terms of value, North America is estimated to be dominant, accounting for over one-third of the total excipients market value by 2015 end. Asia Pacific is estimated to emerge as the fastest growing market among all the emerging regions while revenue from the market in Europe is expected to expand at a healthy CAGR of 6.1% over the forecast period despite the ongoing economic downturn in the region.
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Some of the key players covered in the global pharmaceutical excipients drug market report are BASF SE, Evonik Industries AG, Innophos Holdings Inc., The Lubrizol Corporation, The Dow Chemical Company, Wacker Chemie AG, and Ashland Inc. The report is enriched through identification of company-specific strategies related to excipient raw material sourcing, research and development, market consolidation initiatives, and analyzes of the various market player’s specific strengths, weaknesses, opportunities, and threats.
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