Next generation sequencing is a process of DNA sequencing to determine the precise order of nucleotides within a DNA molecule. Next generation sequencing technology enables rapid sequencing and produces million of DNA and RNA sequence with the use of next generation sequencer. Next generation sequencing (NGS) is also known as high-throughput sequencing. NGS has number of different modern sequencing technologies such as Illumina sequencing and Roche 454 sequencing. NGS provides a low cost and high throughput alternative for sequencing DNA as compare to traditional Sanger sequencing.
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NGS provides its services in the research field such as cancer research, metagenomics, genetic disease research and newborn sequencing. Several NGS platforms provide low cost and high throughput sequencing such as Illumina MiSeq, life technologies ion proton and personal genome machine. Whole-genome sequencing, discovery of transcriptional factor binding sites, non-coding RNA expression profiling and targeted re-sequencing are some of the applications of next generation sequencing technologies. Next generation sequencing is used in various fields such as biological drug discovery, agriculture research, personalized medicines and animal research.
North America followed by the Europe dominates the global next generation sequencing market, due to rising government support towards research and development. Asia is expected to witness high growth in next generation sequencing due to rising investment in India and China on research and development of next generation sequencing.
Low cost DNA sequencing, increasing adoption among researchers, academician and customers and substituting microarray technology by NGS are some of the key factors driving the growth for global next generation sequencing market. However, difficulty in maintaining high accuracy and standardization, lack of skilled labor and data analysis are key factors inhibiting the growth for global next generation sequencing market.
Rise in growth of personalized medicine, development in pre-sequencing and NGS bioinformatics solutions and cloud computing are some of the opportunities for global next generation sequencing market. However, the storage and management of enormous data generated by sequencing and its interpretation are some of the challenges for global next generation sequencing market. Increasing number of collaboration and new product launches are some of the trends for global next generation sequencing market.
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Some of the major companies operating in global next generation sequencing market are Agilent Technologies, Inc., Biomatters, Ltd., CLC Bio, 454 Life Sciences Corporation (A Roche Company), Macrogen, Inc., BGI (Beijing Genomics Institute), Illumina, Inc., GATC biotech AG, Life Technology Corporation, EMC Corporation and Dnastar, Inc.
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