Bioactive coatings on metallic implants facilitate joining between the prosthesis and the osseous tissue, and increase the long-term stability and integrity of the implant. These are thin films coated on medical devices to deter bacterial adhesion, improve core functionality of the device, and impart bioactivity along with biocompatibility to the device. One of the earliest successful bioactive coatings was that of heparin-modified surface of a polymer blood oxygenator component trademarked as Caemeda Affinity Blood Oxygenator, Trillium Affinity NT Blood Oxygenator, which received FDA approval.
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Increasing number of bioactive coating medical devices used for surgeries and medical device implants are the major driver for the bioactive materials for coating.
Implantable devices containing thin films of bioactive molecules are rapidly gaining adoption in therapeutic areas of cardiology and orthopedic joint diseases – the two major sources of loss of quality of life and disability currently. Bioactive molecules and generic factors such as increasing incidence of systemic joint diseases, cardiovascular implant and support are driving the demand for bioactive coating devices across the globe. On the other hand, lack of research awareness, high requirement for funding for continued research, and less-developed research infrastructure in middle and low income countries among others are the restraints of market.
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The global market for bioactive coating devices is segmented on the basis of product type, by medical application, by material, and by end-user.
On the basis of product type, the global market is classified into Anti-microbial coatings- also termed as self-fertilizing coatings. Antimicrobial coatings on textiles prevent the degradation of textile fibers, limit the incidence of bacteria, reduce the formation of odor following the microbial degradation of perspiration, and protect users by avoiding the transfer and spread of pathogens.
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