Hemostatic agents prevent the blood loss, and have different site of action in complex coagulation and fibrinolysis pathways. Antifibrinolytic drugs inhibit the activation of plasminogen to plasmin preventing the lysis of fibrin and maintaining the clot stability. These Antifibrinolytic drugs prevent excessive bleeding. Tranexamic acid is used when the risk of hemorrhage is high because of increased fibrinolysis. Aprotinin, a proteolytic enzyme inhibitor which acts on plasmin and kallikrein. Antifibrinolytic drugs have nearly a ubiquitous use during important major surgeries when bleeding is expected most likely. The inhibition of fibrinolytic pathway after the tissue injury has been constantly showing a decrease in postoperative bleeding this ultimately results in the reduction in the need of blood transfusion after operation.
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Growth in healthcare investments, prevalence of angioedema and growing high-risk geriatric population are the major factors driving the global market growth for angioedema treatment. In the next few years the demand for angioedema treatment is expected to increase significantly in the economies such as China and Japan. Rising incidence of hereditary angioedema and high awareness about treatment and the management of angioedema together drive the global hereditary angioedema market.
For treating menorrhagia, Tranexamic acid is widely used, and is also recommended by the current National Institute for Health and Care Excellence guidelines. Tranexamic acid is effective in decreasing the blood loss by almost 40-50%. Etamsylate is used just occasionally to treat menorrhagia.
Geographically, North America is the dominating region in the Antifibrinolytic Drugs market owing to the advancing strict rules at the work place in this region, also due to large number of aging population and broad technical applications of Antifibrinolytic Drugs in the region. Also, rising awareness of Antifibrinolytic Drugs has fueled the Antifibrinolytic Drugs market.US holds the prominent market in the Antifibrinolytic Drugs market in North America trailed by Europe including Germany, France and UK. The Asian market for Antifibrinolytic Drugs is also expected to witness a high CAGR during the coming years. Increased foreign investments in this region will also boost the Antifibrinolytic Drugs market ahead. China and Japan are projected to be the fastest growing in the Antifibrinolytic Drugs market.
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Currently, the global Antifibrinolytic Drugs market is highly competitive owing to the involvement of many established players. Some of the key players in the global Antifibrinolytic Drugs market are Aurobindo Pharma Ltd, Acic Fine Chems, Akorn and Xanodyne Pharmaceuticals.
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