Numerous existing medical devices would benefit from having their surfaces be completely repellent to blood. Venous catheters, for example, would cause less clotting and may have reduced chances for transmitting infection. Researchers at Colorado State University created a set of superhemophobic materials, based on variations of chemically modified titanium, and tested which demonstrate the greatest compatibility with blood while being repulsive to it. Specifically, the investigators watched for platelet adhesion events that lead to blood clots and possible immune rejection.
Intuitively, materials that work well with blood should not be hemophobic. Yet, the researchers have shown that if the material is so repellent of blood that blood doesn’t even recognize its presence, there won’t be an opportunity for unwanted processes to even begin.
The results testing various versions of the titanium sheets showed that ones covered with fluorinated nanotubes had the highest compatibility while being superhemophobic. So far this is still a materials research project that hasn’t been translated to any medical devices for true evaluation, but it’s certainly promising and may eventually affect entire categories of medical devices.
Study in Advanced Healthcare Materials: Hemocompatibility of Superhemophobic Titania Surfaces…
Via: Colorado State