Preclinical imaging (In-VIVO) is used in live animal research for drug development. Preclinical imaging is further used to monitor the treatment response for early indications of efficacy. The technological development of in vivo imaging provides an opportunity for studying disease at the molecular level in a quantitative way. In vivo imaging acts as a bridge between in vitro exploratory and in vivo clinical research which facilitates the direct and fast transfer of preclinical studies on animal models to clinical investigation in man. The key disease areas targeted with in vivo preclinical imaging are cancers, autoimmune diseases, neurological disorders, and cardiovascular diseases. Use of preclinical imaging in cancer is about 70% which is followed by autoimmune diseases and neurological disorders which accounts for 36% and 32%, respectively.
Factors such as technological advancements, and growth in prevalence of chronic disease such as cancer, cardiovascular, rheumatoid arthritis, and neurological disorders are driving the preclinical imaging market globally. According to American Cancer Society, 14.1 million new cancer cases were diagnosed and 8.2 million cancer deaths in 2012. Technological development such as “Aspect’s M2,” a preclinical imaging product developed by Aspect imaging, is used for drug development but without the cost, complexity, and technical burden of traditional MRI systems. Other factors such as growing demand for non-invasive imaging techniques and government funding for research and development activities are estimated to fuel the preclinical imaging market. However, the growth of the preclinical imaging market is hindered by some factors such as high product price that decreases the adoption rates in academic institutions and limited number of application of each modality, discouraging the sale of products.
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