In the past two decades, disposable or single-use bioreactors have grown in prominence in the pharmaceutical industry. It comprises a disposable bag in place of a typical culture vessel, which is made up of glass or stainless steel. Biotechnology applications, which need a great number of cells, require a solution for the growth of large-scale cell cultures. In these cases, bioreactors serve as a solution in the research and development scale-up applications, large scale biotechnology, process development, and bio production processes.
Browse: Single-Use Bioreactors Market
The industry’s willingness towards the utilization of single-use bioreactors is presently influenced by the product’s value, the need for the step in the respective procedure, and the time taken for product production and development.
Single-use Bioreactors Market: Advantages and Disadvantages
The advantages of single-use bioreactors are ample as compared with the conventional bioreactors. Different drugs can be produced by the pharmaceutical companies utilizing the same facility without any compromises on the quality and function in several consecutive batches.
In these situations, the major challenge is to make sure that no remains are left from previous batches. Additionally, no cleaning and sterilization is needed during the utilization of disposable bioreactors. Saving time and cost are among the major advantages conferred by the use of single-use bioreactors. On the basis of the agitation of the culture medium as well as its flexibility, single-use bioreactors are of various types, such as stirred flexible disposable bioreactors, stirred rigid disposable bioreactors, non-stirred disposable bioreactors, and non-stirred flexible bioreactors.
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However, there are also certain disadvantages associated with the utilization of single-use bioreactors. Manufacturing disposable types of equipment of a high quality in a central facility is a huge challenge, because these manufacturing processes require different core competencies. Single-use sensors, at times, lack in performance and, hence, at times are unable to meet the requirements for process control. Additionally, having materials that are free from leachables/extractables still remains a challenge.
Europe and North America Surfaced as the Largest Regional Markets
The single-use bioreactors market is expanding worldwide owing to the advantages connected to the utilization of disposable reactors, such as safeguarding against cross-contamination, time management, cost-effectiveness, and the establishment of novel products.
Geographically, the market can be segmented into North America, Asia Pacific, Europe, and Rest of the World. Amongst these, North America and Europe stood as the biggest markets owing to the presence of a majority of the burgeoning biopharmaceutical companies in these regions.
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This market is predicted to expand in Latin America and Asia Pacific owing to the presence of a large number of multinational biopharmaceutical companies, which are establishing and expanding their manufacturing facilities in these regions. The most significant future advancement in single-use bioreactor technology will be the rise in capacity in order to coordinate with common largeâ€‘scale process capacities. Processing of multiple smaller batches being controlled centrally utilizing singleâ€‘use bioreactors is another significant step in the evolution of the technology. Improvements will be seen in the control, automation levels, data logging, and design of singleâ€‘use bioreactors.
Key players in the market include Thermo GE Healthcare, Fisher Hyclone, PBS Biotech, Sartorius Stedim Biotech, Xcellerex, Merck Millipore, and Cellexus Limited.
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