Major depressive disorder (MDD), also known as clinical depression or major depression, is widely recognized as a mood disorder that may lead to a variety of emotional and physical problems. MDD is characterized by persistent feelings of sadness, anger, irritability or frustration, loss of interest in activities, and overeating or loss of appetite that can last from days to months, and alternates with episodes of wellness. Little is known about the etiology of MDD; however, research suggests that there may be combinations of genetic, biological, environmental, and psychological factors that potentially increase the risk of MDD.
GlobalData epidemiologists forecast that the 12-month total prevalent cases of MDD in the 7MM will increase from 37,157,683 12-month total prevalent cases in 2015 to 38,142,749 12-month total prevalent cases in 2025, at an Annual Growth Rate (AGR) of 0.27%. The US will have the highest number of 12-month total prevalent cases of MDD among the 7MM throughout the forecast period, while Japan will have the least number of 12-month total prevalent cases of MDD. As GlobalData epidemiologists used steady prevalence proportions of MDD over the forecast period, the growth in 12-month total prevalent cases in each market can be attributed to the change in population demographics.
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GlobalData epidemiologists utilized country-specific and nationally representative peer-reviewed publications to forecast the 12-month total prevalent cases of MDD. The use of consistent methodology across the 7MM allows for a meaningful comparison of the forecast of 12-month total prevalent cases of MDD in these markets. Additionally, the 12-month total prevalent cases of MDD in each of the 7MM are segmented by severity, which can be of importance for predicting the prognosis and course of treatment. Lastly, the 12-month total prevalent cases of MDD in each of the 7MM are further segmented by age and sex in order to provide a more detailed analysis of the patient population.
– The Major Depressive Disorder (MDD) EpiCast Report provides an overview of the risk factors and global trends of MDD in the 7MM (US, France, Germany, Italy, Spain, UK, and Japan). It includes a 10-year epidemiology forecast of 12-month total prevalent cases of MDD segmented by age (18-19 years, in five-year increments from ages 20-84 years, and ending at ages 85 years and older), sex, and severity in these seven markets.
– The MDD epidemiology report is written and developed by Masters- and PhD-level epidemiologists.
– The EpiCast Report is in-depth, high quality, transparent and market-driven, providing expert analysis of disease trends in the 7MM.
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List of Tables
Table 1: DSM-IV Diagnostic Criteria for MDD 8
Table 2: Risk Factors and Comorbidities for MDD 9
Table 3: Prevalence of the Most Frequent Psychiatric Comorbidities in Individuals With and Without MDD, Ages 18-64 Years 10
Table 4: 7MM, Total Prevalence (%) of MDD According to the DSM-IV Criteria, ≥18 Years 12
Table 5: 7MM, Total Prevalence (%) of MDD According to the DSM-III Criteria 12
Table 6: 7MM, Sources Used to Forecast the 12-Month Total Prevalence of MDD 14
Table 7: Sources Used to Forecast the 12-Month Total Prevalent Cases of MDD by Severity 15
Table 8: 7MM, Sources Not Used in Epidemiological Forecast for the 12-Month Total Prevalent Cases of MDD 20
Table 9: 7MM, 12-Month Total Prevalent Cases of MDD, Ages ≥18Years, Both Sexes, N, Selected Years 2015-2025 22
Table 10: 7MM, 12-Month Total Prevalent Cases of MDD, by Age, Both Sexes, N (Row %), 2015 23
Table 11: 7MM, 12-Month Total Prevalent Cases of MDD, by Sex, Ages ≥18 Years, N (Row %), 2015 25
Table 12: High-Prescribing Physicians (Non-KOLs), Surveyed by Country, 2016 37
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