Pharmaceutical formulations containing proteins and peptides are usually administered via intravenous or subcutaneous route of administration, because instability and sensitivity towards body fluids. However, owing to rising R&D activities and technological advancements, the researchers have successfully developed protein formulations that are orally administered with no change in therapeutic activity and pharmacokinetic aspects.The market for oral proteins and peptides is expected to show a promising growth, owing to continuous research and development activities, technological advancements and increasing prevalence of chronic disorders such as diabetes, tumors and others. According to the report of International Diabetes Federation, the total number of diabetes patients is expected to increase from 382 million (2013) to 592 million (2035). Such an astonishing rise in number of people diagnosed with diabeteswould boost the growth of this market during the study period. In addition, due to increasing R&D activities, large number of oral protein formulations are expected to be introduced in the market. However, lack of awareness, high cost of the R&D are some of the hurdles that could impose restrictions to the growth of the market.
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The market of oral proteins and peptides is segmented on the basis of drugs available, such as Linaclotide, IN-105 (inslulin), Ostora, Octreolin, Plecantide and others. The market is also segmented on the basis of technologies used for the development of formulations, such as Gastrointestinal Permeation Enhancement Technology (GIPET), Eligen, Peptelligence, oral antibody platform, Multi-Matrix Systems (MMX) and others. Moreover, the market is segmented on the basis of geography, such as North America, Europe, Asia-Pacific and Rest of the World (RoW). At present, North America region is the most prominent market of the oral protein and peptide formulations. However, Asia-Pacific and certain countries in the RoW region are the most promising markets in near future.
Some of the major players present in the market includes ZydusCadilla Healthcare, Sanofi-Aventis LLC, Roche, Inc., Pfizer, Inc., Novartis AG, Johnson & Johnson, and Abbott Laboratories amongst others.
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