Obsessive compulsive disorder is a chronic and long-lasting disorder in which a person has, behaviors (compulsions), reoccurring thoughts (obsessions) and uncontrollable that he or she feels the urge to repeat over and over. Common obsessions are fear of dirt or contamination by germs, fear of making a mistake, fear of causing harm to another and others and common compulsions are refusing to shake hands or repeatedly washing hands, bathing, showering or repeatedly checking things, such as locks or stoves or touch doorknobs.
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The symptoms can interfere with all aspects of life, such as school, personal relationships and work. The other symptoms includes tic disorder such as brief, sudden, repetitive movements, such as facial grimacing, eye blinking and other eye movements, head or shoulder jerking and shoulder shrugging. Obsessive compulsive disorder appears in different ways, and not every person has the same symptoms, many people have combinations of various obsessive compulsive disorder symptoms. Children and teens with obsessive compulsive disorder does not realize that their obsessions and compulsions are excessive or even view their symptoms as a disorder that can be treated.
The causes of obsessive compulsive disorder are not clear exactly, but risk factors include: genetics, brain structure and functioning and environment. Obsessive compulsive disorder symptoms can sometimes be associated with other neurological conditions, such as stroke, brain tumor, and trauma to the frontal lobe, Huntington’s disease, Tourette’s syndrome, front temporal dementia, or hypoxia. Obsessive compulsive disorder is typically treated with medication, psychotherapy or a combination of the two. Serotonin reuptake inhibitors and selective serotonin reuptake inhibitors are used to help reduce obsessive compulsive disorder symptoms. Selective serotonin reuptake inhibitors includes fluoxetine, fluvoxamine and sertraline.
Cognitive behavioral therapy is also used for the treatment of obsessive compulsive disorder, the therapy can take place in individual, group or family sessions. Cognitive therapy helps patients correct their obsessions and compulsions by identifying unrealistic thoughts and beliefs. Atypical antipsychotics have also proven to be helpful in low doses. Deep-brain stimulation is FDA approved to treat chronic and severe cases of obsessive compulsive disorder, with reports of successful treatment from case reports and small trials. Deep-brain stimulation is an invasive procedure in which probes are inserted directly into brain tissue, and carries a risk of adverse effects including infection, intracerebral hemorrhage, acute mood changes, and seizures. Antipsychotics includes risperidone, quetiapine, olanzapine, ziprasidone. Because the distressing thoughts may be embarrassing or shameful, obsessive compulsive disorder patients often do not reveal them to healthcare professionals or family members.
Psychosurgery is used to alleviate symptoms of obsessive compulsive disorder in patients who do not respond to medications or behavioral therapy. Intensive treatment programs are available for obsessive compulsive disorder. Some programs last only a weekend while others require a three-month stay at a treatment center. At these facilities, obsessive compulsive disorder patients undergo intensive individual, group and family cognitive therapy every day. A specifically devised medication regimen is also used. Other therapeutic methods are in development. Research involving the manipulation of neurotransmitters is currently under way.
Geographically, the obsessive compulsive disorder therapeutics market has been segmented into North America, Europe, Asia Pacific, Latin America and Middle East and Africa. North America occupies the largest market share followed by Europe. According to Understanding Obsessive Compulsive Disorder, in U.S. approximately 3.3 million people have obsessive compulsive disorder. The high awareness level in this region led the market of obsessive compulsive disorder or expansion significantly. According to World Health Organization, higher occurrence of obsessive compulsive disorder was found in Russia, Eastern Europe, Middle East, Africa, South and Central America with most severe incidence in Argentina and Uruguay. Asia Pacific has shown striking increase in its growth rate for the obsessive compulsive disorder market. Rising population, increase in disposable income, and increase in awareness level are some key factors driving the growth of obsessive compulsive disorder in Asia Pacific market.
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The major players operating in this market include F. Hoffmann-La Roche Ltd., Pfizer Inc., The Lundbeck Foundation, AstraZeneca Plc, Torrent Pharmaceuticals Limited, Johnson & Johnson, Novartis AG, Eli Lilly and Company and Morningside Healthcare Limited among other significant players worldwide.
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