Neurogenesis is a mechanism through which neurons are generated through neural stem cells or progenitor cells. Neurogenesis is active during pre natal development and is responsible for populating the brain with neurons. This significant process of neuron generation takes place in two parts of the brain namely subventricular zone and hippocampus. The rate of neurogenesis mechanism is mainly influenced by hormones such as testosterone. Neural stem cells are multipotent self renewing cells that are capable of generating phenotypes of the nervous system. These cells include astrocytes, oligodendrocytes and neurons. While, neural progenitor cells are the lines of stem cell division that usually undergo limited number of stem cell division invivo. Neural stem cells have been promising approach for the treatment of nervous system disorders.
Factors such as increase in geriatric population, investment in R&D and improved understanding of the nature of neurologic diseases are driving the neural stem and progenitor cell products market growth globally. Since, aged population is more prone to brain disorders therefore; increase in geriatric population will likely increase the neural stem and progenitor cell products market worldwide. Additionally, as per the World Health Organization, by 2020 nearly 14.1% of the world population will suffer from neurologic disorders which would further lure manufacturers for the production of neural stem and progenitor cell products. Also as per the estimates approximately 5.4 million Americans were diagnosed with Alzheimer’s in 2012. Of these nearly one in eight people aged 65 years and above has Alzheimer’s disease. Additionally, 4% are under age 65, 44% are between age 75 to 84 and 46% are 85 years or older are diagnosed with Alzheimer’s. Hence, collectively all of the mentioned factors would increase the demand for neural stem cell products.
The market for neural stem and progenitor stem cells can be categorized on the basis of applications and end users. Neurotoxicity testing, neural tissue engineering, personalized medicines, cellular therapies for the treatment of central nervous system conditions and drug target validation and testing and others are some of the major applications of the neural stem and progenitor cell products market. Academic labs, commercial labs, private labs and government laboratories are some of the major customers of the market. Development of neural stem cells products by the pharmaceutical sector represents a significant opportunity as development of new drugs is costly and bringing new drugs into the market is highly unpredictable.
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Geographically, North America is the largest neural stem and progenitor cell products market due to extensive technological advancements and presence of major market players in this region. Moreover, increasing awareness among people about neurological condition and government initiatives will further accentuate the neural stem and progenitor cell products market in this region. Europe held the second largest neural stem and progenitor cell products market followed by Asia-Pacific and Rest of the World. Asia-Pacific is considered as an emerging market due to strong forecasted economic growth (healthcare infrastructure, healthcare facility and product expansion) in some Asian countries such as India, China, Japan and Malaysia.
Some of the key players in the neural stem and progenitor cell products market are Stem Cells Technologies, EMD Millipore, Life Technologies Corporation, Thermo Fisher Scientific, Neural Stem, BD Biosciences, Lonza, NeuroGeneration, AlphaGenix, Inc. SA Biosciences, R&D Systems and others. Some of these manufacturers offer array of products for neural stem cell culture, media, supplements, growth factors and substrates.
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