Biosimulation is computer aided mathematical simulation of biological systems and processes. Biosimulation is used for model based calculation of biological systems. The global biosimulation market is expected to grow at a considerable rate from 2011 to 2018.The primary reason for the growth of biosimulation is the increasing use of pharmacodynamic and pharmacokinetic (PKPD) modeling in pre-clinical drug development. PKPD is the most widely used method in drug development.
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Increasing importance of advanced techniques to reduce the drug development and discovery cost is the primary factor for the growth of the global biosimulation market. Also, increased spending on health care, advanced computer technology, improved simulation and modeling tools will also contribute to the growth of the biosimulation market. Lack of standardization in biosimulation methodology, lack of knowledge about biological processes and systems and risk of failing of drugs in biosimulation are the major hurdles for this market. However, innovative technology will help to overcome these barriers.
Based on application, the biosimulation market could be segmented into two major categories -drug discovery and drug development. Drug discovery is further segmented into target identification, lead identification, target validation, and lead optimization. Drug development biosimulation is segmented into pre-clinical testing and clinical trial. The global market for biosimulation could be segmented into North America, Europe, Asia-Pacific, and Rest of the World (ROW).
North America is the largest regional market by revenue for biosimulation and holds more than one third of the global biosimulation market share. Europe is the second largest regional market and represents the fastest growing regional market for the biosimulation industry. Growth in the European market is due to efforts of regulatory bodies in promoting advanced technologies in drug discovery and development. The biosimulation market in Asia is at a development stage and growing at a relatively slower rate due to lack of skilled workers and infrastructure facilities.
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Some of the major players in this industry include Schrodinger, Accelrys, Certara, Rhenovia, Simulation Plus, ACD/Labs, LeadScope, CCG, Entelos, Physiomics, Genedata, Insilico Biotechnology, Archimedes, Insilico biosciences and Compugen.
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