Cancer cells exhibit a fundamentally modified metabolism that creates an environment in the body to support the growth of tumors and malignancy. In-depth understanding of the biochemical characters of cancer has facilitated the understanding and implementation of several different cancer profiling platforms.
Deciphering the scope of altered metabolism of cancer cells, its relevance in disease pathogenesis, and its further potential in the discovery of suitable therapeutics, thus, demands development in technologies for the identification of modified enzymes and cellular structures in cancer.
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Large scale cancer profiling methods such as genomics, proteomics, and metabolomics are being used to explicate metabolic pathways responsible for tumorigenesis and metastasis. These endeavors in the field of cancer profiling and pathways have facilitated not only in understanding the basic biochemistry of cancer, but have also helped in the discovery of modalities of efficient cancer therapy.
The growth of this market is driven by increase in demand for new and specific biomarkers useful in drug discovery. The high growth of the biomarker market is influenced by the increase in demand for biomarkers by the aging population and the emerging economies of Asia-Pacific.
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The major cancer profiling technologies currently being employed are genomic profiling, transcriptomic profiling, epigenomic profiling, proteomics, glycomics, and metabolomics. Gene expression profiling facilitated the efficient detection and measurement of different gene transcripts in a single RNA sample. Continuous evolution in methods such as microarray analysis, quantitative real-time PCR, and multiplex PCR has helped in efficient decoding of molecular mechanisms in cancer. These methods are also helpful in the discovery of new drug targets and diagnostic biomarkers.
Some of the major market players in the global cancer profiling and pathways market are Life Technologies, Applied Biosystems, and Affymetrix.