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High incidence of life threatening adverse effects in many cases of combination therapy and high cost of treatment associated with multiple agents are some of the major drivers of single agent chemotherapy market. Rising number of cancer cases globally will further enhance the growth of this market since chemotherapy is considered to be one of the most effective treatments of the cancer. According to the Cancer Research U.K., 14.1 million cancer cases were recorded globally in 2012 alone in the U.K.
In addition, factors such as less toxicity and impairment of quality of life have widened the acceptance of single agent chemotherapy amongst patients. Furthermore, huge investment in research and development by pharmaceutical companies, extensive academic and industry collaborations and innovation in targeted drug delivery technologies have shown immense possibilities in future growth of single agent chemotherapy market. However, increasing resistance against single chemotherapy agent over the course of treatment and delayed tumor response rate as compared to combination therapy are some of the key factors restraining the growth of single agent chemotherapy.
The global single agent chemotherapy market has been segmented on the basis of major drug classes, type of cancer and chemotherapy drugs. Major classes of single agent chemotherapy drugs are alkylating agents, anti-tumor antibiotics, mitotic inhibitors, antimetabolites and miscellaneous single chemotherapy drugs. Alkylating agents is the largest segment of single agent chemotherapy market.
By type of cancer, single agent chemotherapy market has been segmented into brest cancer, lung cancer, gastrointestinal cancer, genitourinary cancer, head & neck cancer, endocrine cancer, gynecologic cancers, blood cancer, brain cancer and others. Brest cancer constituted the largest segment by type of cancer for single agent chemotherapy market in 2013. Some of the most popular single agent chemotherapy drugs include chlorambucil, fludarabine, bendamustine, mitomycin, teniposide, vinblastine, carboplatin, dacarbazine, procarbazine, doxorubicin, ramucirumab, ado-trastuzumab and imatinib.
Based on geography, the single agent chemotherapy market is segmented into North America, Europe, Asia-Pacific and Rest of the World (RoW). The North American region was recognized as the largest single agent chemotherapy market across the globe in 2013, followed by Europe. Ongoing robust research activities for the development of drugs and biologics, high prevalence of cancer and astronomically high healthcare expenditure are some of the major driving factors for growth in these regions.
Cancer is the second most common cause of death in the U.S. The National Institutes of Health estimated overall costs of cancer in 2010 at USD 157 billion. Asia-Pacific is expected to be a one of the fastest growing markets during the forecast period from 2014 to 2020. This high growth is primarily due to improving economic condition in countries such as India, China and Malaysia, and large population base in Asia-Pacific region.
Some of the key players operating in this market globally include Sanofi-Aventis, Novartis Pharmaceuticals, Pfizer Inc., Eli Lilly & Co, ImClone Systems Inc., GlaxoSmithKline AstraZeneca, Schering-Plough, Boehringer Ingelheim, Bristol-Myers Squibb, Teva Pharmaceuticals Industries and Roche.