Regenerative medicine is an emerging field in the healthcare industry concerned with the repair, replacement, and regeneration of damaged human tissue and organs. This includes damage from age-related degeneration, congenital defects, accidents, or diseases. Due to its vital contribution, regenerative medicine is becoming widely popular in the treatment of neurological, cardiovascular, musculoskeletal, and orthopedic conditions. Bone and joint conditions are among the leading applications of regenerative medicine. The viability of several synthetic alternatives to bones and joints is one of the key points that have driven investment in regenerative medicine in the recent past.
The increasing incidence of bone and joint diseases and injuries, brought about by the chronic damage done by the unhealthy lifestyle of most urban consumers and the rising number of vehicular and sports accidents, is the key driver for the global bone and joint regenerative medicine market. The sedentary lifestyle and chronically unhealthy diets of many urban individuals leave them prone to diseases that weaken or damage the bones, leading to a greater demand for orthopedic implants.
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The competitive landscape of the global regenerative medicine market includes players such as CONMED Corporation, Anika Therapeutics Inc., Arthrex, Inc., Baxter International Inc., Smith & Nephew PLC, DePuy Synthes Inc., Stryker Corporation, Medtronic Inc., and Zimmer Holdings Inc. Though North America and Europe were the largest markets for regenerative medicines, the market players are increasingly shifting their focus on the emerging economies across Asia Pacific such as India, South Korea, Japan, and China. These countries are registering an increased demand for various bone and joint reconstructive products such as Osteocel Plus (NuVasive Inc.), Trinity Evolution (Orthofix Inc.), and INFUSE Bone Graft (Medtronic Inc.) owing to the rapid growth of the healthcare sector and the rising pool of patients. The market players are investing in rigorous research and development initiatives for innovative products.
In terms of application, the global regenerative medicine market is broadly categorized into osteoarticular diseases, bone graft substitutes, autogeneic bones, allogeneic bones, and others. Bone graft substitutes had witnessed the highest demand in 2012 owing to the rise in orthopedic surgeries. A number of key market players have developed innovative bone graft substitutes. However, the demand for bone graft substitutes is expected to decline in future. “The post-implantation rejection associated with bone graft substitutes is the key factor restricting their demand,” a TMR analyst points out.
Demand for Tissue Engineering to Rise amid High Cost of Biomaterials
Regenerative medicine is an emerging branch of medical science and is being extensively used to treat cardiovascular disease, musculoskeletal disease, and orthopedic disorders. The growing prevalence of bone and joint disorders and the rise in orthopedic surgeries have fuelled the demand for regenerative medicines. Furthermore, technological innovations in stem cell therapy, biomaterials, and tissue engineering have supported the growth of the global regenerative medicines market. However, regulatory constraints pose a threat to the development of regenerative medicines. “Ethical issues related to allogeneic bone grafts and stem cell therapy, and post implantation infections are impeding the growth of the overall market,” the analyst states.
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Technology has played a pivotal part in the success of regenerative medicines. Favorable reimbursement policies had augmented the demand for biomaterials in 2012. However, tissue engineering is being increasingly preferred over biomaterials. In fact, during the period between 2013 and 2019, tissue engineering is anticipated to expand at the fastest pace. “The high cost of biomaterials has led to their decreased adoption among patients,” the analyst mentions.
The global regenerative medicine market is anticipated to expand at a CAGR of 12.8% during the period between 2013 and 2019. The overall market stood at a valuation of US$2.6 bn in 2012 and is projected to be worth US$6.5 bn by 2019.