Ophthalmology is the branch of medical science that deals with the management and study of anatomy, physiology, and diseases related to the human eye. Globally, the incidence of eye disorders and vision loss are becoming major public health issues. Some of the major eye diseases include age-related macular degeneration, glaucoma, cataract, bulging eyes, diabetic macular edema, ocular hypertension, retinal detachment, uveitis, and refractive errors. Choroidal neovascular membranes refer to the new blood vessels that grow below the retina and disrupt vision. The area between the retina and the sclera (the white part of eye), where these blood vessels grow is called choroid.
Choroid is responsible for oxygen and nutrients supply to the eye. Choroidal neovascularization (CNV) occurs when new blood vessels start growing in the choroid and rupture the barrier between retina and choroid. When choroidal neovascular membrane leaks in the retina, it causes vision loss. Choroidal neovascularization leads to various serious eye diseases such as wet age-related macular degeneration and histoplasmosis. In addition, choroidal neovascularization can also lead to, eye trauma and myopic macular degeneration. Myopic macular degeneration commonly occurs in aged people due to extreme elongation of the eyeball. It even leads to loss of vision. The global market for choroidal neovascularization is increasing due to increase in aged population and growing incidence of eye diseases.
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