Single-use bioprocessing systems is a significant part of biopharmaceutical development and production processes. These systems have made the production of clinical test materials cost-effective and flexible. The market for single-use bioprocessing systems is expected to grow at a double-digit, and in two-third of the bio processes this single-use bioprocessing systems are used. It is used in a broad range of techniques in cases of biopharmaceutical purification, mixing, filtration, upstream expression, storage, and separations. The technology aims on the development of disposable accessories and bio-processing equipment to manufacture biopharmaceutical product.
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With the rising adoption and acceptance of single-use bioprocessing systems in upstream commercial (GMP) product manufacture, currently there is rising growth of upstream market. High market growth is expected in the next five to seven years as it is integrated to commercial-scale/GMP single-use systems. There are many advantages associated with the usage of single-use bioprocess system disposal options, such as negligible or very low operating cost, advantage of recycling of the device, and reduces risk of cross-contamination. Compared to stainless steel, they are faster to implement, and cost-effective. The initial cost of investment is also comparatively lower. The systems are comparatively environmental compatible. But there are some challenges associated with the system. As, the high cell density and product titers, the classical process is far superior process. The safety of the commercial market is the primary concern of the manufacturers. There are regulatory obstacles involved in plastic safety. There are also stability and other inflexibility issues, and to overcome it latest technological advancements have been made by different companies which would provide flexibility of the system. Moreover, supply chain can be a major challenge involving polymer manufacturers and downstream formulators.
The single use bioprocessing systems market can be segmented on the basis of application. The segment can be categorized into research and development (R&D) support single use systems and GMP/commercial single use systems. R&D support single use systems comprises containers, tubing, sampling systems, connectors, mixers, disposable bioreactors, purification devices and columns and probes and sensors. GMP single use systems comprise manifolds, tubing storage containers and disposable used in stainless steel based bioreactors. Of these two segments research and development accounts for the majority share of the market the commercial and GMP segment occupied almost one-fourth of the market share.
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Geographically, the single-use bioprocessing systems market can be segmented into four major regions: North America, Europe, Asia Pacific, and Rest of the World (RoW). North America holds the leading position in the single-use bioprocessing systems market followed by Europe. Asia Pacific is the most promising market for single-use bioprocessing systems market due to various emerging economies. Growing demand for the use of biodisposables in the manufacture of vaccines, monoclonal and other biopharmaceuticals is a major factor that is expected to drive the market in the regions. There is intense market rivalry observed for single use bioprocessing systems. The major players operating in this market include Sartorius Stedim Biotech S.A., Thermo Fisher Scientific, Merck KGaA, GE Healthcare, while the other prominent vendors includes Eppendorf AG, Broadley-James Ltd., Parker Hannifin Corporation, Saint-Gobain Corporation, STI Components Inc., Tarpon Biosystems Inc., Cellexus Ltd., Pall Corporation and others. Among all the players ThermoFisher Scientific occupies the largest share of the market. These players dominate the market due to innovative and highly effective products.