BIOTRONIK has announced that the latest generation DREAMS (DRug Eluting Absorbable Metal Scaffold) device has been implanted for the first time in a patient as part of a clinical study in Europe. Made from a magnesium alloy covered with a polymer and limus, a common drug coating that prevents restenosis, the entire device is slowly absorbed by the body after it helps develop a healthy lumen.
By comparison, Abbot’s ABSORB, the world’s first bioresorbable drug eluting “scaffold”, is made from polylactide, a plant derived thermoplastic aliphatic polyester.
From the device info page:
- Absorbable Metal Scaffolds (AMS) provide temporary vessel support after angioplasty
- A temporary metallic scaffold is attractive due to an acute result that is similar to a conventional stent; however, nothing foreign remains in the vessel following the absorption
- Absorbable metal scaffolds also allow long-term restoration of vasoreactivity and vessel remodelling in less than 1 year
- Magnesium is an essential element of the human body with good mechanical properties, thus magnesium is considered as an ideal material for absorbable scaffolds
- A Drug Eluting Absorbable Magnesium Scaffold was developed (DREAMS) to provide temporary scaffolding, while limiting excess tissue growth with the release of an anti-proliferative drug
- The DREAMS device is currently under investigational use in the BIOSOLVE studies
Product info page: DREAMS – Drug Eluting Absorbable Metal Scaffold…