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Microneedle Patch Makes TB Tests Painless for Patients and Clinicians

August 28th, 2013 Scott Jung Diagnostics, Medicine, Nanomedicine, Pediatrics, Public Health

u-of-w-microneedle-patchTuberculosis is a contagious, potentially lethal disease that is said to have infected one-third of the world’s population in its latent form. Sometime during your life, you’ve probably received a Mantoux test for TB (aka “the bubble test”) in which a sample of purified TB protein derivative is injected just beneath the skin. The Mantoux test, however, is tricky to administer as the injection must be made at a precise angle and depth in the arm, and there are a number of factors that can easily cause false negative or false positive results.

microneedle-patchResearchers at the University of Washington have developed a patch made up of tiny microneedles coated with purified TB protein derivative which could make TB testing much more painless for both patients and clinicians. As the microneedles measure just 750 micrometers long, they’re too short to reach nerves in the skin that register pain, so applying the patch feels like putting on a band-aid. Moreover, because the delivery of the TB protein using the patch depends on the length of the microneedle rather than the angle, the patch test will be far easier for clinicians to administer than a Mantoux test and will ensure that the TB derivative is being properly injected.

Environmentalists will be pleased too; another benefit of the microneedle patch is that it is biodegradable. The microneedles are made of chitin, a naturally-occurring, tough material found in the exoskeletons of insects and crustaceans.

Journal abstract from Advanced Healthcare Materials: Chitin Microneedles for an Easy-to-Use Tuberculosis Skin Test

Article from UW: Microneedle patch could replace standard tuberculosis skin test…

Scott Jung

Scott Jung (@scottjung) is a Silicon Valley-based medical and health technology reporter and advocate, with a focus on wearables, telemedicine, and health technology in emerging countries. He has represented Medgadget at CES and Digital Health Summit, TEDMED, Stanford Medicine X, and SXSW. Always on the lookout for innovative medical technology worldwide, Scott has been invited to visit Colombia, Poland, and many other countries around the world to share how medtech is enriching the lives of its people. Scott holds a B.S. degree in Biomedical Engineering from the University of Southern California and an M.S. degree in Medical Product Development Management from San José State University. Scott is always looking for the next big thing in medical technology and digital health. Interested in helping him transform lives? Get in touch with him at http://scottju.ng

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