Last month we reported news of a Japanese research team successfully imaging the neural activity of zebrafish brains as delicious paramecium was presented in front of the animals. Now another team, this time from Howard Hughes Medical Institute, has reported doing a very similar thing, also introducing a genetically modified version of the calcium indicator GCaMP to the fish DNA.
It’s not clear which team’s methodology provides more spatial and temporal resolution, but certainly the American team’s results have greater potential for use in music videos:
Flashback: Thoughts Visualized in Brains of Zebrafish Looking for Dinner
Article in Nature Methods: Whole-brain functional imaging at cellular resolution using light-sheet microscopy