• Popular
    • Medicine
    • Radiology
    • Cardiology
    • Surgery
    • Nanomedicine
    • Military Medicine
    • Rehab
  • Categories
    • Exclusive
    • A-D
      • Anesthesiology
      • Art
      • Cardiac Surgery
      • Cardiology
      • Critical Care
      • Dentistry
      • Dermatology
      • Diagnostics
    • E-I
      • Emergency Medicine
      • ENT
      • Genetics
      • Geriatrics
      • GI
      • Informatics
    • M-N
      • Medicine
      • Military Medicine
      • Nanomedicine
      • Net News
      • Neurology
      • Neurosurgery
      • Nuclear Medicine
    • O-P
      • Ob/Gyn
      • Oncology
      • Ophthalmology
      • Orthopedic Surgery
      • Pathology
      • Pediatrics
      • Plastic Surgery
      • Psychiatry
      • Public Health
    • R-V
      • Radiation Oncology
      • Radiology
      • Rehab
      • Reproductive Medicine
      • Space Medicine
      • Sports Medicine
      • Surgery
      • Thoracic Surgery
      • Urology
      • Vascular Surgery
  • SUBSCRIBE
  • Submit PR
  • About
  • Follow
    • Facebook
    • Twitter
    • Linkedin
    • Youtube
    • Instagram
    • RSS
  • Submit PR
  • Log in
Medgadget
Medgadget
  • Popular
    • Medicine
      Levels Is Making Metabolism and Blood Glucose Tracking Accessible To Everyone

      Levels Is Making Metabolism and Blood Glucose Tracking Accessible To Everyone

      CRISPR Combined with Glowing Proteins for Viral Detection

      CRISPR Combined with Glowing Proteins for Viral Detection

      Biomimetic Construct Models Burn Injuries

      Biomimetic Construct Models Burn Injuries

      Moving Cells Using Ultrasound

      Moving Cells Using Ultrasound

    • Radiology
      Imaging Technique Reveals Contraction Patterns During Labor

      Imaging Technique Reveals Contraction Patterns During Labor

      Moving Cells Using Ultrasound

      Moving Cells Using Ultrasound

      Ultrasound Catheter to Treat Hypertension

      Ultrasound Catheter to Treat Hypertension

      Antibacterial Smart Sutures Visible in CT Scans

      Antibacterial Smart Sutures Visible in CT Scans

    • Cardiology
      Scientists Grow Electrodes Inside The Body

      Scientists Grow Electrodes Inside The Body

      Patient-Specific Soft Robotic Heart Replicas for Treatment Planning

      Patient-Specific Soft Robotic Heart Replicas for Treatment Planning

      Tiny Patch for Cardiac Ultrasound Imaging

      Tiny Patch for Cardiac Ultrasound Imaging

      Belt Monitors Heart Failure Patients

      Belt Monitors Heart Failure Patients

    • Surgery
      Biomimetic Construct Models Burn Injuries

      Biomimetic Construct Models Burn Injuries

      Exclusive Look at HandX Robotic-Assisted Surgical Device from Human Xtensions

      Exclusive Look at HandX Robotic-Assisted Surgical Device from Human Xtensions

      Self-Assembling Peptides as a Bioink

      Self-Assembling Peptides as a Bioink

      3D Bioengineered Skin Grafts Fit Complex Anatomy

      3D Bioengineered Skin Grafts Fit Complex Anatomy

    • Nanomedicine
      Bottlebrush Particle for Synergistic Drug Combinations

      Bottlebrush Particle for Synergistic Drug Combinations

      Extra Hot Nanoparticles for Cancer Therapy

      Extra Hot Nanoparticles for Cancer Therapy

      Making Tumors Tastier for the Immune System

      Making Tumors Tastier for the Immune System

      Improved Membrane Coating for Anti-Cancer Nanoparticles

      Improved Membrane Coating for Anti-Cancer Nanoparticles

    • Military Medicine
      Device Measures Hemoglobin More Accurately in Dark Skin

      Device Measures Hemoglobin More Accurately in Dark Skin

      Fingertip Sensor Measures Lithium Levels in Sweat

      Fingertip Sensor Measures Lithium Levels in Sweat

      Fabric Makes Electricity from Movement to Power Wearables

      Fabric Makes Electricity from Movement to Power Wearables

      Wearable Uses Microneedles to Track Metabolism

      Wearable Uses Microneedles to Track Metabolism

    • Rehab
      Empowering Stroke Survivors: Interview with Kirsten Carroll, CEO at Kandu Health

      Empowering Stroke Survivors: Interview with Kirsten Carroll, CEO at Kandu Health

      Smart Walking Stick for Visually Impaired People

      Smart Walking Stick for Visually Impaired People

      Implantable Device Adheres to Muscle, Treats Atrophy

      Implantable Device Adheres to Muscle, Treats Atrophy

      Non-Invasive Spinal Modulation for Cerebral Palsy

      Non-Invasive Spinal Modulation for Cerebral Palsy

  • Categories
    • Exclusive
    • A-D
      • Anesthesiology
      • Art
      • Cardiac Surgery
      • Cardiology
      • Critical Care
      • Dentistry
      • Dermatology
      • Diagnostics
    • E-I
      • Emergency Medicine
      • ENT
      • Genetics
      • Geriatrics
      • GI
      • Informatics
    • M-N
      • Medicine
      • Military Medicine
      • Nanomedicine
      • Net News
      • Neurology
      • Neurosurgery
      • Nuclear Medicine
    • O-P
      • Ob/Gyn
      • Oncology
      • Ophthalmology
      • Orthopedic Surgery
      • Pathology
      • Pediatrics
      • Plastic Surgery
      • Psychiatry
      • Public Health
    • R-V
      • Radiation Oncology
      • Radiology
      • Rehab
      • Reproductive Medicine
      • Space Medicine
      • Sports Medicine
      • Surgery
      • Thoracic Surgery
      • Urology
      • Vascular Surgery
  • SUBSCRIBE
  • Submit PR
  • About
  • Log in
  • Submit PR
  • Follow
    • Facebook
    • Twitter
    • Linkedin
    • Youtube
    • Instagram
    • RSS

Dried Vaccines Without The Need for Needles (w/video)

February 6th, 2013 Stanley Darma Medicine, News, Public Health

Vaccine PatchThe skin is a great site to access the systemic circulation of the human body. And that’s exactly where we want the effect of vaccinations to occur. Researchers at King’s College London have showed a way to deliver dried live vaccine to the skin with a microneedle assay and thereby enable immune cells in the skin to set off an immune response. They published their results this week in Proceedings of the National Academy of Sciences.

The microneedle array has microneedles made of sucrose which dissolve once inserted into the skin. Professor Geissmann and his team used this microneedle array with a stable dried version of a live modified adenovirus-based candidate HIV vaccine in sucrose. After observing how the vaccine dissolved in the skin, they also identified the specialized immune cells, a sub-set of specialized dendritic cells, which initiate the immune response for this type of vaccine.

The initiated immune response was equivalent to vaccination using standard needle delivery.  Another thing is that the dried vaccine on the microneedle array can be kept at room temperature. It is a great achievement to dry a live vaccine and still maintain the effectiveness after administration, especially through a painless method like a microneedle array.

If this drying method will prove itself in similar results with other vaccines, there won’t be any need for refrigeration of the vaccines anymore. Together with a painless administration on the skin, this can reduce the costs, improve safety and reduce the risks and pain compared to hypodermic needle vaccination.

 

News release: Injection-free vaccination…

Article abstract in PNAS: Langerin negative dendritic cells promote potent CD8+ T-cell priming by skin delivery of live adenovirus vaccine microneedle arrays

Earlier on Medgadget: Microneedle Patch for Measles Vaccination on Horizon

Stanley Darma

Stanley is an MD and PhD candidate at the Academic Medical Center Amsterdam, the Netherlands. His research field is in ophthalmology and optical coherence tomography, making amazing pictures of and performing precise measurements in the human retina everyday.

Sponsored
Venture builder BHV Partners launches Conus Airway to improve anaesthesia  and respiratory surgery

Venture builder BHV Partners launches Conus Airway to improve anaesthesia and respiratory surgery

FDA Expands Indications for Use of FibroScan® for Comprehensive Liver Management

FDA Expands Indications for Use of FibroScan® for Comprehensive Liver Management

machineMD and Varjo revolutionize the diagnosis of brain disorders with a VR-based eye-tracking solution 

machineMD and Varjo revolutionize the diagnosis of brain disorders with a VR-based eye-tracking solution 

Ax-Surgi Hemostat gets FDA Clearance for Surgical Bleeding Control

Ax-Surgi Hemostat gets FDA Clearance for Surgical Bleeding Control

Clarius Report Finds 85% of Clinicians Believe Ultrasound Leads to Better Patient Outcomes

Clarius Report Finds 85% of Clinicians Believe Ultrasound Leads to Better Patient Outcomes

interviews & reviews
Levels Is Making Metabolism and Blood Glucose Tracking Accessible To Everyone

Levels Is Making Metabolism and Blood Glucose Tracking Accessible To Everyone

Imagene Profiles Cancer Biomarkers in Real Time

Imagene Profiles Cancer Biomarkers in Real Time

Empowering Stroke Survivors: Interview with Kirsten Carroll, CEO at Kandu Health

Empowering Stroke Survivors: Interview with Kirsten Carroll, CEO at Kandu Health

Alpha TAU Killing Tumors With Highly Targeted Alpha Radiation

Alpha TAU Killing Tumors With Highly Targeted Alpha Radiation

Neuroimmune Modulation for Inflammatory Disease: Interview with Dr. Simhambhatla, President and CEO of SetPoint Medical

Neuroimmune Modulation for Inflammatory Disease: Interview with Dr. Simhambhatla, President and CEO of SetPoint Medical

Exclusive Look at HandX Robotic-Assisted Surgical Device from Human Xtensions

Exclusive Look at HandX Robotic-Assisted Surgical Device from Human Xtensions

Balance Boards to Stay Active in the Offfice: Interview with Joel Heath, CEO of FluidStance 

Balance Boards to Stay Active in the Offfice: Interview with Joel Heath, CEO of FluidStance 

  • Subscribe
  • Contact us
  • Submit
  • About
  • Back to top
Medgadget

Medical technologies transform the world! Join us and see the progress in real time. At Medgadget, we report the latest technology news, interview leaders in the field, and file dispatches from medical events around the world since 2004.

  • About
  • Editorial policies
  • Contact
  • Terms of Service
  • Privacy
  • Submit press release
  • Advertise
© Medgadget, Inc. All rights reserved. | The Medical Revolution Will Be Blogged.
Please support this website by adding us to your whitelist in your ad blocker. Ads are what helps us bring you premium content! Thank you!
Posting....
  • Facebook
  • Twitter
  • LinkedIn
  • Reddit
  • Email