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New South African Source for Molybdenum-99 to Soothe Supply Worries in Medical Radioisotope Market

March 11th, 2011 Medgadget Editors News

bq345h.pngAfter Canada’s Chalk River reactor was taken offline in May 2009 for more than a year due to a heavy water leak, medical radioisotope suppliers have been looking to expand their sources. Covidien, having received FDA approval a year ago to source molybdenum-99 from Poland’s Maria nuclear research reactor, has now received similar clearance to purchase molybdenum-99 derived from low-enriched uranium from a South African reactor. Molybdenum-99 is used to generate technetium-99m, the radiomarker most commonly used in nuclear medicine.

Tc-99m is produced when Mo-99 decays following uranium irradiation. The approval by the FDA allows use of LEU-based Mo-99 supplied by South Africa’s NTP Radioisotopes, Ltd., a subsidiary of the Nuclear Energy Corporation of South Africa, in Tc-99m generator production at Covidien’s Maryland Heights, MO, manufacturing facility.
In January, 2009, the Company launched a collaborative effort with Babcock & Wilcox Technical Services Group (B&W) to develop solution-based reactor technology for LEU-based medical isotope production, a unique approach designed to provide an efficient domestic supply source. The project combines Covidien’s expertise in radiopharmaceutical production and global regulatory approvals with B&W’s patented liquid phase nuclear technology. Covidien is also developing plans for conversion of its Mo-99 processing facility in Petten, the Netherlands, to facilitate use of LEU.

Press release: Covidien Receives FDA Approval for South African-Produced Medical Isotope Based on Low-Enriched Uranium
Flashbacks: New Radioisotope Supplier to Fill Gaping Hole in Market; Project Aims for Medical Isotope Production Without Use of Nuclear Reactors

Medgadget Editors

Medical technologies transform the world! Join us and see the progress in real time. At Medgadget, we report the latest technology news, interview leaders in the field, and file dispatches from medical events around the world since 2004.

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