At the Medica 2010 in Dusseldorf, Mego Afek, a Kibbutz Afek, Israel firm, is launching the Angio Press pneumatic compression system for treatment of symptoms of Peripheral Arterial Occlusive Disease (PAOD) in patients at Fontaine stages 2 and 3 PAOD. According to the company, the device intermittently applies high pressure to the legs in a regular cycle, enhancing extremities blood flow in patients with PAOD, and prevents deep vein thrombosis and lymphedema.
The Angio Press(R) provides moderately applied high-pneumatic pressure through pressure garments that are filled with air in an intermittent sequence from the feet and ankles up through the calves of patients diagnosed with PAD. At the end of the sequence, pressure is blocked for four seconds and released when the garments are deflated, followed by a 40-second pressure-free interval.
The availability of Angio Press is based on a multi-center, randomized, controlled, four-arm open label study. According to data from 28 subjects in Germany and Israel, patients in the treatment group received platelet medication (either aspirin or clopidigrel), walking exercises and Angio Press treatment either once daily for three hours or twice daily for 1.5 hours. These patients demonstrated improvement in the distance at which they first experienced pain when exerting themselves (initial claudication) from 75 meters at baseline to 145 meters after the three-month treatment period, a mean improvement of 69 meters. This was compared to the control group, which received medication and exercise regimen only, and demonstrated improvement from 79.5 meters to 96 meters, a mean improvement of only 13 meters.
Other results included change in total distance walked until the patient could no longer continue (absolute claudication), for which the treatment group demonstrated a mean improvement of 62.5 meters, compared to the control group, which demonstrated a worsening by a mean of 12 meters.