How quickly can your coronary stents reendothelialize following implantation, if ever? We bet not too quick. How about 26 days post-implantation? OrbusNeich, a company headquartered in Hong Kong, has just announced these results from an optical coherence tomography (OCT) evaluation of a patient that was implanted with company’s two new Genous Bio-engineered R coronary stents. The procedure was performed at the Queen Mary Hospital in Hong Kong on a 62-year-old male with acute MI. Featuring a proprietary bio-engineered surface that is coated with anti-CD34 antibodies, thought to capture circulating Endothelial Progenitor Cells (EPCs) that have CD34 antigen molecules on their membranes, these devices are specifically designed to enhance endothelialization.
More from the press release:
Following a diagnosis of acute thrombotic occlusion of the proximal left anterior descending artery (LAD), with critical lesions identified in the proximal and mid LAD and a chronic total occlusion (CTO) of the proximal right coronary artery (RCA), the patient, a 62-year-old male, received two 2.5 mm diameter Genous Bio-engineered R stents. The proximal stent was 23 mm in length, and the distal stent was 13 mm in length. At 26 days post-implantation, physicians conducted an OCT assessment when a staged procedure was performed to the CTO on the RCA with implantation of an additional 2.5 mm diameter by 23 mm length Genous Bio-engineered R stent.
"This is the first documentation of complete endothelialization after 26 days of Genous stent implantation, showing the pro-healing effect in vivo," said Prof. Lee.
Genous is OrbusNeich’s patented endothelial progenitor cell (EPC) capture technology that promotes the accelerated natural healing of the vessel wall after the implantation of blood-contact devices such as stents. The technology consists of an antibody surface coating that attracts EPCs circulating in the blood to the device to form an endothelial layer that provides protection against thrombosis and modulates restenosis.
To learn more about Genous technology, check out this brochure: Healing within Hours (.pdf)…
OrbusNeich Cardiology Products …
OrbusNeich Media Kit …
Press release: 100 Percent Coverage of Struts and Complete Neointimal Coverage of OrbusNeich’s Genous™ Bio-engineered R stent™ Demonstrated 26 Days Post-Implantation in STEMI Patient (.pdf)
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