Cook Medical is touting results of the latest study confirming more clinical benefits of the firm’s biologic mesh for hernia repair. A three year 70 patient study was just published in the American Journal of Surgery that showed a significant reduction in post-op pain when compared to a traditional polypropylene synthetic mesh.
From a Cook press statement:
Research findings showed that 11 percent of patients treated with synthetics experienced chronic postoperative pain that limited daily activities, most often resulting from the mesh characteristics as opposed to surgical technique. By contrast, patients in the study treated with Biodesign Inguinal Hernia Graft experienced a lower degree of postoperative pain both at rest and when coughing or moving. Additionally, a three-year follow-up no evidence of hernia recurrence was seen in the study patients treated with the Biodesign graft.
Some details from the study abstract:
Seventy male patients underwent Lichtenstein’s hernioplasty (n = 35 in the SIHM group and n = 35 in the PP group). At 3 years after surgery, there were 2 deaths (5.7%) in the PP group and 1 death (2.9%) in the SIHM group (not significant [NS]). Although the study was underpowered to evaluate the recurrence rate, only 1 recurrence (2.9%) was seen in the PP group (NS). Although a significant decrease in postsurgical pain incidence was never observed among patients in the SIHM group, a significantly lower degree of pain was detected at rest and on coughing at 1, 3, and 6 months and on movement at 1, 3, and 6 months and 1, 2, and 3 years. A significant decrease in postsurgical incidence and degree of discomfort when coughing and moving were observed among patients in the SIHM group at 3 and 6 months and at 1, 2, and 3 years after surgery.
Press release: Clinical Study: Biologic Grafts Reduce Postoperative Pain While Creating a Repair as Durable as Synthetic Mesh in Treating Inguinal Hernias …
Abstract in The American Journal of Surgery: Inguinal hernia repair with porcine small intestine submucosa: 3-year follow-up results of a randomized controlled trial of Lichtenstein’s repair with polypropylene mesh versus Surgisis Inguinal Hernia Matrix
Product page: Cook Biodesign …
Flashbacks: Cook Medical’s Biodesign Hernia Graft ; Cook Releases Biologic Graft Info Site CookBiodesign.com; Cook Medical’s Biologic Mesh Looks Good in Study