Gambro, a manufacturer of dialysis products based in Denver, Colorado, is releasing the next generation of high-flux dialyzers, devices that the company hopes will take high-porosity, biocompatible, high-flux hemodialysis to a new, and even an environmentally friendly, level.
The following features and benefits are taken from Gambro press statement:
The Polyflux Revaclear and Polyflux Revaclear MAX high-flux dialyzers feature a new membrane that is more efficient and more selective while retaining the same proven 3-layer membrane structure as the existing Polyflux dialyzer. The membrane is composed of a unique blend of the polymers PAES (Polyarylethersulfone) and PVP (Polyvinylpyrrolidone).
Studies have demonstrated that the Revaclear dialyzers’ advanced design offers enhanced performance with a smaller, smoother membrane surface, with the potential to improve patient outcomes and efficiencies for providers:
• A smoother membrane surface area results in reduced thrombogenic potential
• Improved hollow fiber geometry, with thinner fibers, allows Revaclear MAX to achieve the same degree of solute clearance as the original Polyflux, despite a significant reduction in membrane surface area.
• A β2-microglobulin clearance that results in significant potential for lowering β2-microglobulin levels which may help to reduce morbidity and mortality in patients.
• Improved device design provides a uniform flow distribution in both the blood and dialysate compartments, contributing to enhanced solute clearance and low thrombogenicity.
The design and performance ensure that all adult patients can be treated using only two sizes of dialyzers — (Polyflux Revaclear (1.4m2) and Polyflux Revaclear MAX (1.8m2).