Optical coherence tomography (OCT), a technology often described as combining the principles of ultrasound with the imaging performance of a microscope, is thought to be particularly useful for future diagnostic devices for ophthalmology. In essence, OCT is a technique that allows the reconstruction of tissue microstructure, based on tomographic images obtained with low intensity light. Bioptigen, Inc., a Duke University spin out, has been recognized with the Frost & Sullivan 2008 North American Excellence in Research Award for its work in implementing OCT for ophthalmic applications. The company believes that its technology one day will provide a very early look at quite a few diseases of the eye and nervous system.
Bioptigen’s SDOCT systems enable researchers and clinicians to resolve the microstructure of the retina in finest detail, including the nerve fiber layer, inner and outer plexiforms, retinal pigment epithelium layers, Bruch’s membrane, and vessels of the choriocapillaris. Additionally, the tissue structures of the cornea, conjunctiva, and sclera can also be clearly visualized with a mere change in focal position and no change in optical irradiance.
The software suite works in tandem with the scanners and SDOCT engine to offer intuitive and flexible system control with advanced functionality. Real-time acquisition and display, combined with customizable, protocol-driven operations, help ensure maximum workflow efficiency. Volume intensity projections generate en-face images (similar to the fundus images taken of the retina) that enable accurate cross-sectional image registration. Doppler processing quantifies system dynamics and flows.
Optical Coherence Tomography technology page at Bioptigen…
Press release (.pdf)…
Product page: High Throughput High Resolution Biomedical Imaging from Bioptigen, Inc…
Flashbacks: Optical Coherence Tomography for Multiple Sclerosis; FDA Approves Optical Coherence Tomography (OCT) ; Optical Coherence Tomography System by Imalux; Optical Coherence Tomography: Positive Results in Clinical Study Reported.
