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Polyzene-F Nanocoating for Cardiac Stents

January 24th, 2008 Medgadget Editors Cardiology

A study presented at the 20th annual International Symposium on Endovascular Therapy (ISET), a conference that wrapped up yesterday, has shown that cobalt chromium stents covered with poly[bis(trifluroexthoxy)phosphazene], or Polyzene®-F nanothin surface coating, have shown “promise in opening and healing blocked heart arteries without the life-threatening dangers of drug-eluting stents.” Polyzene-F is a product of CeloNova BioSciences, Inc., a Newnan, GA company.

Polyzene®-F is a unique chemical compound with an extensive array of bioscience and industrial applications.
When applied to or mixed with other substances, Polyzene®-F makes them better. It represents a quantum leap forward in synthesized inorganic polymers, offering superior properties for a variety of applications.
Polyzene®-F allows for a diverse range of applications on a multitude of substrates, including other polymers, metals and ceramics. It can be applied as a surface coating of less than 50 nanometers as well as up to 150-200 nanometers (and beyond).
The method of application, which may include coating, extrusion, weaving, or electro-spinning, will beneficially endow the base substrate with the superior properties of Polyzene®-F and can be tailor-made to suit the desired application…

  • Biocompatible — Polyzene®-F is not detected by the body, has a high molecular weight and is ultra-pure
  • Anti-inflammatory — does not release carbon radicals known to invite inflammatory response
  • Bacterial resistant — hydrophobic material prevents bacterial infiltration and negatively charged material repels gram negative bacteria
  • Promotes endothelial (healthy) cell growth — the undetectable nature eliminates inflammatory cell reactions while the surface inhibits adhesion of platelets that lead to blood coagulation and thrombosis
  • Outstanding coating adhesion properties — Polyzene®-F retains its bio-beneficial properties when mixed or extruded
  • Polyzene®-F substantially improves the safety and effectiveness of medical products, making them highly biocompatible, anti-inflammatory, resist infection, and promote healing.
    Manufactured under pharmaceutical GMP standards, it is extremely pure and can be produced in large quantities.
    The applications for Polyzene®-F are virtually limitless, offering improvements to every aspect of daily life.

    The other product in the company’s pipeline is Embozene™ Microspheres, an embolization material that consist of a hydrogel core with Polyzene®-F exterior. Learn more about it from this product brochure (.pdf)…
    Super-Thin Drug-Free Coating ‘Hides’ Stent as it Unblocks Heart Arteries …
    Product page: Polyzene®-F …

    Medgadget Editors

    Medical technologies transform the world! Join us and see the progress in real time. At Medgadget, we report the latest technology news, interview leaders in the field, and file dispatches from medical events around the world since 2004.

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