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Storing Memories In a Petri Dish

May 31st, 2007 Medgadget Editors Neurology


A group of scientists under Dr. Eshel Ben-Jacob at Tel-Aviv University created an experiment that probably demonstrates for the first time the ability of interconnected neurons in vitro to store memories.
From the statement by the American Physical Society:

A new experiment has shown that it’s possible to store multiple rudimentary memories in an artificial culture of live neurons. The ability to record information in a manmade network of neurons is a step toward a cyborg-like integration of living material into memory chips. The advance also may help neurologists to understand how our brains learn and store information.
Itay Baruchi and Eshel Ben-Jacob of Tel-Aviv University used an array of electrodes to monitor the firing patterns in a network of linked neurons. As previous studies have shown, simply linking the neurons together leads them to spontaneously fire in coordinated patterns. In the study published this month in the journal Physical Review E the researchers found that they could deliberately create additional firing patterns that coexist with the spontaneous patterns. They claim that these new firing patterns essentially represent simple memories stored in the neuron network.
To create a new memory in the neurons, the researchers introduced minute amounts of a chemical stimulant into the culture at a selected location. The stimulant induced a second firing pattern, starting at that location. The new firing pattern in the culture along coexisted with the original pattern. Twenty-four hours later, they injected another round of stimulants at a new location, and a third firing pattern emerged. The three memory patterns persisted, without interfering with each other, for over forty hours.
In addition to producing the first chemically operated neuro-memory chip, the researchers propose that their work implies that chemical stimulation may be crucial to learning and memory formation in living organisms.

Abstract: Towards neuro-memory-chip: Imprinting multiple memories in cultured neural networks …
Press release: A living memory chip, black holes on the loose, and a clearer picture of ocean currents …
(hat tip: Engadget)
Also: Tel-Aviv University’s magazine has an expose of the work done by university’s scientists in the area of bio- and nanotech: TAU Review Spring 2007 (large .pdf file)

Medgadget Editors

Medical technologies transform the world! Join us and see the progress in real time. At Medgadget, we report the latest technology news, interview leaders in the field, and file dispatches from medical events around the world since 2004.

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