• Popular
    • Medicine
    • Radiology
    • Cardiology
    • Surgery
    • Nanomedicine
    • Military Medicine
    • Rehab
  • Categories
    • Exclusive
    • A-D
      • Anesthesiology
      • Art
      • Cardiac Surgery
      • Cardiology
      • Critical Care
      • Dentistry
      • Dermatology
      • Diagnostics
    • E-I
      • Emergency Medicine
      • ENT
      • Genetics
      • Geriatrics
      • GI
      • Informatics
    • M-N
      • Medicine
      • Military Medicine
      • Nanomedicine
      • Net News
      • Neurology
      • Neurosurgery
      • Nuclear Medicine
    • O-P
      • Ob/Gyn
      • Oncology
      • Ophthalmology
      • Orthopedic Surgery
      • Pathology
      • Pediatrics
      • Plastic Surgery
      • Psychiatry
      • Public Health
    • R-V
      • Radiation Oncology
      • Radiology
      • Rehab
      • Reproductive Medicine
      • Space Medicine
      • Sports Medicine
      • Surgery
      • Thoracic Surgery
      • Urology
      • Vascular Surgery
  • SUBSCRIBE
  • Submit PR
  • About
  • Follow
    • Facebook
    • Twitter
    • Linkedin
    • Youtube
    • Instagram
    • RSS
  • Submit PR
  • Log in
Medgadget
Medgadget
  • Popular
    • Medicine
      Magnetic Dressing Improves Diabetic Wound Healing

      Magnetic Dressing Improves Diabetic Wound Healing

      Eko’s Newest CORE 500 Stethoscope: A Review

      Eko’s Newest CORE 500 Stethoscope: A Review

      Microfluidic System Incorporates Eight Organ Tissues for Drug Testing

      Microfluidic System Incorporates Eight Organ Tissues for Drug Testing

      Suction Cup Delivers Drugs Through Cheek

      Suction Cup Delivers Drugs Through Cheek

    • Radiology
      Shear-Thinning Biomaterial for Embolic Applications: Interview with Upma Sharma, President and CEO of Arsenal Medical

      Shear-Thinning Biomaterial for Embolic Applications: Interview with Upma Sharma, President and CEO of Arsenal Medical

      Ultrasound-Equipped Bra Monitors for Breast Cancer

      Ultrasound-Equipped Bra Monitors for Breast Cancer

      Portable and Radiation-Free Imaging with Magnetic Nanoparticles

      Portable and Radiation-Free Imaging with Magnetic Nanoparticles

      Imaging Technique Reveals Living Brain Tissue in its Complexity

      Imaging Technique Reveals Living Brain Tissue in its Complexity

    • Cardiology
      Eko’s Newest CORE 500 Stethoscope: A Review

      Eko’s Newest CORE 500 Stethoscope: A Review

      Shear-Thinning Biomaterial for Embolic Applications: Interview with Upma Sharma, President and CEO of Arsenal Medical

      Shear-Thinning Biomaterial for Embolic Applications: Interview with Upma Sharma, President and CEO of Arsenal Medical

      Ultrasound-Equipped Bra Monitors for Breast Cancer

      Ultrasound-Equipped Bra Monitors for Breast Cancer

      3D Printed Heart Muscle Beats

      3D Printed Heart Muscle Beats

    • Surgery
      Magnetic Dressing Improves Diabetic Wound Healing

      Magnetic Dressing Improves Diabetic Wound Healing

      Sensor Monitors Transplanted Organs for Signs of Rejection

      Sensor Monitors Transplanted Organs for Signs of Rejection

      Refillable Device for Drug Delivery Past the Blood-Brain Barrier: Interview with Mike Maglin, CEO at CraniUS

      Refillable Device for Drug Delivery Past the Blood-Brain Barrier: Interview with Mike Maglin, CEO at CraniUS

      Droplet Battery Harnesses Ionic Gradients for Bioelectronic Implants

      Droplet Battery Harnesses Ionic Gradients for Bioelectronic Implants

    • Nanomedicine
      Nanorobots Release Reactive Oxygen Species to Kill Fungal Biofilms

      Nanorobots Release Reactive Oxygen Species to Kill Fungal Biofilms

      Bottlebrush Nanoparticles Deliver Immunostimulatory Drugs

      Bottlebrush Nanoparticles Deliver Immunostimulatory Drugs

      Nanoparticles Deliver mRNA Therapy to the Lungs

      Nanoparticles Deliver mRNA Therapy to the Lungs

      Nanoparticles Get Lymphatic Vessels Pumping

      Nanoparticles Get Lymphatic Vessels Pumping

    • Military Medicine
      Wearable Can Take Multiple Sweat Samples

      Wearable Can Take Multiple Sweat Samples

      Wound Dressing Detects Infection, Changes Color

      Wound Dressing Detects Infection, Changes Color

      Device Measures Hemoglobin More Accurately in Dark Skin

      Device Measures Hemoglobin More Accurately in Dark Skin

      Fingertip Sensor Measures Lithium Levels in Sweat

      Fingertip Sensor Measures Lithium Levels in Sweat

    • Rehab
      Stretchable E-Skin for Robotic Prostheses

      Stretchable E-Skin for Robotic Prostheses

      Glasses Provide Audible Prompts for Blind Wearers

      Glasses Provide Audible Prompts for Blind Wearers

      A Wearable to Manage Parkinson’s Motor Symptoms: Interview with Lucy Jung, CEO at Charco Neurotech

      A Wearable to Manage Parkinson’s Motor Symptoms: Interview with Lucy Jung, CEO at Charco Neurotech

      Robotic Ankle Helps with Postural Control in Amputees

      Robotic Ankle Helps with Postural Control in Amputees

  • Categories
    • Exclusive
    • A-D
      • Anesthesiology
      • Art
      • Cardiac Surgery
      • Cardiology
      • Critical Care
      • Dentistry
      • Dermatology
      • Diagnostics
    • E-I
      • Emergency Medicine
      • ENT
      • Genetics
      • Geriatrics
      • GI
      • Informatics
    • M-N
      • Medicine
      • Military Medicine
      • Nanomedicine
      • Net News
      • Neurology
      • Neurosurgery
      • Nuclear Medicine
    • O-P
      • Ob/Gyn
      • Oncology
      • Ophthalmology
      • Orthopedic Surgery
      • Pathology
      • Pediatrics
      • Plastic Surgery
      • Psychiatry
      • Public Health
    • R-V
      • Radiation Oncology
      • Radiology
      • Rehab
      • Reproductive Medicine
      • Space Medicine
      • Sports Medicine
      • Surgery
      • Thoracic Surgery
      • Urology
      • Vascular Surgery
  • SUBSCRIBE
  • Submit PR
  • About
  • Log in
  • Submit PR
  • Follow
    • Facebook
    • Twitter
    • Linkedin
    • Youtube
    • Instagram
    • RSS

ApoSense™ Technology

November 21st, 2006 Medgadget Editors Diagnostics, Genetics

Globes [online] is reporting that an Israeli biotech NeuroSurvival Technologies Ltd. (NST) has raised $5 million from Meditech, a venture capital firm. NST has developed technology called ApoSense™, that identifies cells undergoing apoptotic process, a programmed cellular death, and allows binding and accumulation of specific markers within these cells in vivo.
Here’s how the technology works:

ApoSense™ is a set of original, small, rationally-designed molecules, specially designed for clinical use. The ApoSense™ technology is based on a thorough analysis of the apoptotic process, coupled with the implementation of molecular nanotechnology concepts, as follows:

  • An original characterization, by NST, of a set of changes in cell membrane that differentiate between normal and apoptotic cells. This set of features is termed the “cellular fingerprints of apoptosis”.
  • Based on this original characterization, ApoSense™ molecules were designed as multi-functional non-peptide molecules, capable of selectively detecting these “cellular fingerprints of apoptosis”. ApoSense™ biological activity is based on NSTs’ original “Interfacial NanoSwitch™” concept, whereby a molecular switch is activated upon recognition of apoptotic cell membrane features, allowing the ApoSense™ molecule to bind to the apoptotic cell membrane and enter and accumulate within the cell.
  • ApoSense™ detects the apoptotic cell from the early stages of the death process. Its recognition of the apoptotic cell is universal, irrespective of cell type or apoptotic trigger.
  • Importantly, ApoSense™ has a modular structure, allowing for versatile attachment of various imaging moieties for clinical imaging or of a drug to be targeted into apoptosis-inflicted cells and tissues. The ApoSense™ technology is applicable to various imaging modalities.
  • One type of imaging marker was a fluorophor attached to ApoSense™ , Fl- ApoSense™ , allowing for its fluorescence detection upon binding to apoptotic cells. In another study, a tritium-labeled compound, 3H- ApoSense™ was used to allow for sensitive and quantitative measurement of ApoSense™ uptake. For In Vivo clinical molecular imaging, ApoSense™ was labeled with 18F radioactive isotope , 18F- ApoSense™ , allowing its detection by the positron emission tomography…

    The technology page…

    Medgadget Editors

    Medical technologies transform the world! Join us and see the progress in real time. At Medgadget, we report the latest technology news, interview leaders in the field, and file dispatches from medical events around the world since 2004.

    Sponsored
    Ark Surgical Performs First Hysterectomies in the USA with its FDA-Cleared LapBox for Manual Morcellation

    Ark Surgical Performs First Hysterectomies in the USA with its FDA-Cleared LapBox for Manual Morcellation

    PACKAGING COMPLIANCE LABS WELCOMES NEW CFO, BERNADETTE LEGARETTA

    PACKAGING COMPLIANCE LABS WELCOMES JENN GOFF, VP SALES, MARKETING, AND INNOVATION

    Clarius Debuts its First Dual-Array Wireless Handheld Scanner Enabling Whole-Body Views of Superficial to Deep Anatomy

    Clarius Debuts its First Dual-Array Wireless Handheld Scanner Enabling Whole-Body Views of Superficial to Deep Anatomy

    National Liver Health Awareness Month Highlights the Urgent Need for Liver Disease Prevention

    National Liver Health Awareness Month Highlights the Urgent Need for Liver Disease Prevention

    interviews & reviews
    A Wearable to Manage Parkinson’s Motor Symptoms: Interview with Lucy Jung, CEO at Charco Neurotech

    A Wearable to Manage Parkinson’s Motor Symptoms: Interview with Lucy Jung, CEO at Charco Neurotech

    Eko’s Newest CORE 500 Stethoscope: A Review

    Eko’s Newest CORE 500 Stethoscope: A Review

    Shear-Thinning Biomaterial for Embolic Applications: Interview with Upma Sharma, President and CEO of Arsenal Medical

    Shear-Thinning Biomaterial for Embolic Applications: Interview with Upma Sharma, President and CEO of Arsenal Medical

    Refillable Device for Drug Delivery Past the Blood-Brain Barrier: Interview with Mike Maglin, CEO at CraniUS

    Refillable Device for Drug Delivery Past the Blood-Brain Barrier: Interview with Mike Maglin, CEO at CraniUS

    UV-Free Air Decontamination: Interview with Sorel Rothschild, VP at Quantum Innovations

    UV-Free Air Decontamination: Interview with Sorel Rothschild, VP at Quantum Innovations

    EarliPoint Evaluation System for ASD Diagnosis: Interview with Tom Ressemann, CEO of EarliTec Dx

    EarliPoint Evaluation System for ASD Diagnosis: Interview with Tom Ressemann, CEO of EarliTec Dx

    Visually Guided Uterine Biopsies in Physician’s Office: Interview with Allison London Brown, CEO of LUMINELLE

    Visually Guided Uterine Biopsies in Physician’s Office: Interview with Allison London Brown, CEO of LUMINELLE

    • Subscribe
    • Contact us
    • Submit
    • About
    • Back to top
    Medgadget

    Medical technologies transform the world! Join us and see the progress in real time. At Medgadget, we report the latest technology news, interview leaders in the field, and file dispatches from medical events around the world since 2004.

    • About
    • Editorial policies
    • Contact
    • Terms of Service
    • Privacy
    • Submit press release
    • Advertise
    © Medgadget, Inc. All rights reserved. | The Medical Revolution Will Be Blogged.
    Please support this website by adding us to your whitelist in your ad blocker. Ads are what helps us bring you premium content! Thank you!