UK’s Engineering and Physical Sciences Research Council is reporting that a novel portable brain scanner, developed at University College London, could aid the treatment of premature and newborn babies in NICUs. The device is an optical tomography system:
Currently, there are two main ways of performing brain scans on small babies. Magnetic resonance imaging (MRI) can provide data on brain function, but MRI scanners are large and static, and the baby may need to be sedated and wheeled to the scanner for the procedure to be carried out. The other alternative, ultrasound, can be performed at the cot side and is effective at revealing brain anatomy, but cannot show how the brain is actually functioning, e.g. in terms of oxygen supply and blood flow.
Combining the advantages of MRI and ultrasound but avoiding their disadvantages, MONSTIR, the first scanner of its kind in the world, uses an innovative technique called optical tomography to generate images showing how the brain is working. In optical tomography, light passes through body tissue and is then analysed by computer to provide information about the tissue.
A helmet incorporating 32 light detectors and 32 sources of completely safe, low-intensity laser light is placed on the baby’s head. The sources produce short flashes and the detectors measure the amount of light that reaches them through the brain and the time the light takes to travel. A software package also developed with EPSRC funding uses this information to build up a 3D image. This can show which parts of the brain are receiving oxygen, where blood is situated, evidence of brain damage etc.
MONSTIR is the size of a fridge-freezer and takes around 8 minutes to generate an image. The aim is to produce a version that is half this size, 5 times faster, even more accurate and geared for clinical use. The potential use of the technology in breast imaging to aid cancer prevention and treatment is also being trialled.
Dr Adam Gibson is a key member of the multi-disciplinary MONSTIR team at UCL that includes medics, physiologists and mathematicians. He says: “The technology we’re developing has the potential to produce high-quality images at the cot side and is also cheaper than MRI. It could make an important contribution to the care and treatment of critically ill babies. Scanners could be available commercially within a few years.”
The press release…
More at University College London Dept of Medical Physics & Bioengineering…
Flashback: Optical Tomography Device to Examine Tissue-Engineered Vessels, Grafts and Valves