• Popular
    • Medicine
    • Radiology
    • Cardiology
    • Surgery
    • Nanomedicine
    • Military Medicine
    • Rehab
  • Categories
    • Exclusive
    • A-D
      • Anesthesiology
      • Art
      • Cardiac Surgery
      • Cardiology
      • Critical Care
      • Dentistry
      • Dermatology
      • Diagnostics
    • E-I
      • Emergency Medicine
      • ENT
      • Genetics
      • Geriatrics
      • GI
      • Informatics
    • M-N
      • Medicine
      • Military Medicine
      • Nanomedicine
      • Net News
      • Neurology
      • Neurosurgery
      • Nuclear Medicine
    • O-P
      • Ob/Gyn
      • Oncology
      • Ophthalmology
      • Orthopedic Surgery
      • Pathology
      • Pediatrics
      • Plastic Surgery
      • Psychiatry
      • Public Health
    • R-V
      • Radiation Oncology
      • Radiology
      • Rehab
      • Reproductive Medicine
      • Space Medicine
      • Sports Medicine
      • Surgery
      • Thoracic Surgery
      • Urology
      • Vascular Surgery
  • SUBSCRIBE
  • Submit PR
  • About
  • Follow
    • Facebook
    • Twitter
    • Linkedin
    • Youtube
    • Instagram
    • RSS
  • Submit PR
  • Log in
Medgadget
Medgadget
  • Popular
    • Medicine
      Etched Nanopillars Kill Bacteria, Fungi on Titanium Implants

      Etched Nanopillars Kill Bacteria, Fungi on Titanium Implants

      Cells Release Insulin in Response to Music

      Cells Release Insulin in Response to Music

      Microneedle Skin Patch Measures Cancer Biomarkers

      Microneedle Skin Patch Measures Cancer Biomarkers

      Enzyme Treatment Strips Mucins from Cancer Cells

      Enzyme Treatment Strips Mucins from Cancer Cells

    • Radiology
      Ultrasound-Equipped Bra Monitors for Breast Cancer

      Ultrasound-Equipped Bra Monitors for Breast Cancer

      Portable and Radiation-Free Imaging with Magnetic Nanoparticles

      Portable and Radiation-Free Imaging with Magnetic Nanoparticles

      Imaging Technique Reveals Living Brain Tissue in its Complexity

      Imaging Technique Reveals Living Brain Tissue in its Complexity

      Wearable Ultrasound for Deep Tissue Monitoring

      Wearable Ultrasound for Deep Tissue Monitoring

    • Cardiology
      Ultrasound-Equipped Bra Monitors for Breast Cancer

      Ultrasound-Equipped Bra Monitors for Breast Cancer

      3D Printed Heart Muscle Beats

      3D Printed Heart Muscle Beats

      Wireless Patch Monitors, Paces Heart and then Biodegrades

      Wireless Patch Monitors, Paces Heart and then Biodegrades

      Photonic Radar Monitors Breathing from a Distance

      Photonic Radar Monitors Breathing from a Distance

    • Surgery
      Growth Factor-Loaded Microparticles Enhance 3D Bioprinted Muscle

      Growth Factor-Loaded Microparticles Enhance 3D Bioprinted Muscle

      Highly Precise Pressure Sensor for Laparoscopic or Robotic Surgical Tools

      Highly Precise Pressure Sensor for Laparoscopic or Robotic Surgical Tools

      Magnetic Tentacle Robots for Minimally Invasive Procedures

      Magnetic Tentacle Robots for Minimally Invasive Procedures

      Artificial Muscle Changes Stiffness with Voltage

      Artificial Muscle Changes Stiffness with Voltage

    • Nanomedicine
      Nanorobots Release Reactive Oxygen Species to Kill Fungal Biofilms

      Nanorobots Release Reactive Oxygen Species to Kill Fungal Biofilms

      Bottlebrush Nanoparticles Deliver Immunostimulatory Drugs

      Bottlebrush Nanoparticles Deliver Immunostimulatory Drugs

      Nanoparticles Deliver mRNA Therapy to the Lungs

      Nanoparticles Deliver mRNA Therapy to the Lungs

      Nanoparticles Get Lymphatic Vessels Pumping

      Nanoparticles Get Lymphatic Vessels Pumping

    • Military Medicine
      Wearable Can Take Multiple Sweat Samples

      Wearable Can Take Multiple Sweat Samples

      Wound Dressing Detects Infection, Changes Color

      Wound Dressing Detects Infection, Changes Color

      Device Measures Hemoglobin More Accurately in Dark Skin

      Device Measures Hemoglobin More Accurately in Dark Skin

      Fingertip Sensor Measures Lithium Levels in Sweat

      Fingertip Sensor Measures Lithium Levels in Sweat

    • Rehab
      Growth Factor-Loaded Microparticles Enhance 3D Bioprinted Muscle

      Growth Factor-Loaded Microparticles Enhance 3D Bioprinted Muscle

      Brain Computer Interface Decodes Speech and Facial Expressions

      Brain Computer Interface Decodes Speech and Facial Expressions

      Semi-Automated Manufacture of E-Skin Sensors

      Semi-Automated Manufacture of E-Skin Sensors

      Above Elbow Amputee Controls Individual Bionic Fingers

      Above Elbow Amputee Controls Individual Bionic Fingers

  • Categories
    • Exclusive
    • A-D
      • Anesthesiology
      • Art
      • Cardiac Surgery
      • Cardiology
      • Critical Care
      • Dentistry
      • Dermatology
      • Diagnostics
    • E-I
      • Emergency Medicine
      • ENT
      • Genetics
      • Geriatrics
      • GI
      • Informatics
    • M-N
      • Medicine
      • Military Medicine
      • Nanomedicine
      • Net News
      • Neurology
      • Neurosurgery
      • Nuclear Medicine
    • O-P
      • Ob/Gyn
      • Oncology
      • Ophthalmology
      • Orthopedic Surgery
      • Pathology
      • Pediatrics
      • Plastic Surgery
      • Psychiatry
      • Public Health
    • R-V
      • Radiation Oncology
      • Radiology
      • Rehab
      • Reproductive Medicine
      • Space Medicine
      • Sports Medicine
      • Surgery
      • Thoracic Surgery
      • Urology
      • Vascular Surgery
  • SUBSCRIBE
  • Submit PR
  • About
  • Log in
  • Submit PR
  • Follow
    • Facebook
    • Twitter
    • Linkedin
    • Youtube
    • Instagram
    • RSS

Computers Make Big Strides in Predicting Protein Structure

September 19th, 2005 Medgadget Editors News

Predictor@HomeResearchers from the Howard Hughes Medical Institute (HHMI) have shown that there is a a “glimmer of hope” in developing computerized methods to predict protein folding:

“For more than 40 years, people have known the amino acid sequence of a protein specifies its three-dimensional structure, but no one has been able to translate the sequence into an accurate structure,” said senior author David Baker, an HHMI researcher at the University of Washington. “The reason this research is exciting is that we’re showing progress in predicting the structure from the sequence. It’s not that the problem is solved, but that there is hope…”
In the study, a sophisticated computer program folded 17 short strings of amino acids into 100,000 possible variations. When the researchers compared the best predictions to the actual structures solved earlier by other scientists using experimental techniques, they had the same success rate as the best hitters in major league baseball.
“For about one-third of our benchmark set of small proteins, we generated relatively high-resolution structure predictions, with parts of the structures predicted to near-atomic resolution,” said first author Philip Bradley, a postdoctoral fellow in Baker’s lab. “For us, it is a real step forward to achieve structures that are in some way comparable to what you can get by experiments.”
The encouraging results come from a refinement of a sophisticated computer modeling program called Rosetta, first developed several years ago in Baker’s lab. The program works on the premise that proteins collapse into their lowest energy state, like a ball that rolls down a hill until it comes to rest on level ground. The energies of hundreds of thousands of possible shapes generated by the computer are computed, and the lowest energy shape is selected as the prediction.

More in the press release…
Would you like to contribute to the effort to understand protein folding from a protein sequence? Now you can directly be involved with this endeavour and get a spiffy not-so-idle screen saver in the process: join Predictor@home from the Scripps Research Institute, and your idle computer will become a part of the solution!

Medgadget Editors

Medical technologies transform the world! Join us and see the progress in real time. At Medgadget, we report the latest technology news, interview leaders in the field, and file dispatches from medical events around the world since 2004.

Sponsored

Viral Vector Manufacturing in Gene Therapy and Vaccine Development

Health and Clean Air: Why Indoor Ventilation Matters

Health and Clean Air: Why Indoor Ventilation Matters

New Survey Finds Strong Consumer Preference for More Natural Hernia Repair Options

MedTech Outlook 2023 for Latin America Released

MedTech Outlook 2023 for Latin America Released

Packaging Compliance Labs (PCL) Celebrates Site Expansion in Grand Rapids, MI

interviews & reviews
UV-Free Air Decontamination: Interview with Sorel Rothschild, VP at Quantum Innovations

UV-Free Air Decontamination: Interview with Sorel Rothschild, VP at Quantum Innovations

EarliPoint Evaluation System for ASD Diagnosis: Interview with Tom Ressemann, CEO of EarliTec Dx

EarliPoint Evaluation System for ASD Diagnosis: Interview with Tom Ressemann, CEO of EarliTec Dx

Visually Guided Uterine Biopsies in Physician’s Office: Interview with Allison London Brown, CEO of LUMINELLE

Visually Guided Uterine Biopsies in Physician’s Office: Interview with Allison London Brown, CEO of LUMINELLE

AI-Powered Pain Relief: Interview with Claire Smith, VP at Nevro

AI-Powered Pain Relief: Interview with Claire Smith, VP at Nevro

MISHA Knee Shock Absorber: Interview with Anton Clifford, CEO of Moximed

MISHA Knee Shock Absorber: Interview with Anton Clifford, CEO of Moximed

Shelf-Stable Breast Milk Powder: Interview with Dr. Vansh Langer, CEO at BBy

Shelf-Stable Breast Milk Powder: Interview with Dr. Vansh Langer, CEO at BBy

"We Are Electric" by Sally Adee: Medgadget Interviews the Author

"We Are Electric" by Sally Adee: Medgadget Interviews the Author

  • Subscribe
  • Contact us
  • Submit
  • About
  • Back to top
Medgadget

Medical technologies transform the world! Join us and see the progress in real time. At Medgadget, we report the latest technology news, interview leaders in the field, and file dispatches from medical events around the world since 2004.

  • About
  • Editorial policies
  • Contact
  • Terms of Service
  • Privacy
  • Submit press release
  • Advertise
© Medgadget, Inc. All rights reserved. | The Medical Revolution Will Be Blogged.
Please support this website by adding us to your whitelist in your ad blocker. Ads are what helps us bring you premium content! Thank you!
  • Facebook
  • Twitter
  • LinkedIn
  • Reddit
  • Email