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Cell-based therapies, such as those involving the delivery of stem cells, require a way to encapsulate cells inside a protective package in order for them to not be destroyed and washed out by the body. There have been successful attempts to contain therapeutic cells within hydrogels, but the resulting materials were bulky and could not be delivered intravenously. Now, researchers at Harvard's Wyss Institute have developed a way of packaging individual cells within thin-walled hydrogels, which can then be intravenously injected to take on therapeutic tasks. Moreover, their approach results...
When people damage their spinal cords, a lot of the long-term consequences often stem from the body's overreaction to the injury. That's because the blood-brain barrier protecting the spinal cord becomes compromised and overly aggressive immune cells flood in. Now, a team from the University of Michigan has developed a way of using intravenously delivered nanoparticles to reprogram how these immune cells deal with spinal cord injuries once they reach the area of damage. The idea is to reduce inflammation and stimulate the cells to support tissue healing to achieve...

July 19th, 2019 by Medgadget Editors
Light is a great tool for imaging the outside of the body and for looking at the interior using endoscopes, but looking through more than a few millimeters of tissue typically requires other modalities such as X-rays and ultrasound. Using light to peer through skin, muscle, and other soft tissues has remained an elusive goal for many scientists. Now, a team from Carnegie Mellon University has come up with a remarkable new way of using light to look deep into tissues like never before. Since tissues are highly irregular, they...
Withings is releasing two new wireless blood pressure monitors, the BPM Core and BPM Connect, one of which is a bit more than just a BP cuff. As always, the French company has given a lot of attention to the design of these cuffs, giving them a user-friendly, comfortable look. The BPM Connect is a fairly traditional BP cuff, though it does sync with a smartphone to allow users to see their readings and store them for the future. It measures systolic and diastolic blood pressure, as well as heart...

July 18th, 2019 by Medgadget Editors
Artificial skin with the ability to feel is a major research goal for engineers working on improving prosthetic technology. Researchers in the past have created materials with sensors spread over a few square inches, but these have typically had a number of limitations. One thing that causes many such electronic skins to be impractical is the complex wiring that is required to make hundreds, if not thousands, of independent sensors work together. The other issue is that by scaling up to make ever larger pieces of e-skin, vastly more signals...

July 18th, 2019 by Medgadget Editors
Nanolive, a spinoff company of École polytechnique fédérale de Lausanne (EPFL) in Switzerland, has just introduced a holographic microscope that can image live cells at high resolution over extended time periods. Nanolive's CX-A device relies on a low energy light beam to penetrate the sample, which does not interfere with internal cell activity. At every exposure, the system creates a 3D dataset of the sample, down to resolutions below 200 nanometers, which it can do repeatedly for hours at a time. Since entire 96-well plates can be imaged by the...
Chemotherapy is challenging for patients, as it can be terribly brutal on their bodies, but also for physicians trying to figure out which medication to deliver. Now, a new device has been developed at Rutgers University that can test whether a given chemo agent works on a patient's specific tumor. The idea is that a tumor biopsy is used to seed the device. Chemo agents are then added to see whether they kill the patient's tumor cells. This is measured using a special biosensor that relies on multifrequency impedance spectroscopy...
Dysfunction of the pancreas is related to a number of diseases, most famously diabetes. Conditions such as cystic fibrosis-related diabetes (CFRD), are particularly difficult to study in a laboratory setting, but researchers at Cincinnati Children’s Hospital Medical Center have now developed a device, and an accompanying methodology, to mimic the functionality of the human pancreas. The technology is already being used to answer important questions about how CFRD comes about and will certainly help in solving other medical mysteries. The team's microfluidic device has two chambers separated by a porous...
HER2 (human epidermal growth factor receptor 2) is a protein that is associated with some particularly aggressive forms of breast cancer. The presence of high concentrations of this protein seems to lead to the growth of tumors, so inactivating HER2 may help to stop the spread of certain strains of cancer in the body. An existing technique involves introducing an antibody that can block HER2 from binding to other things, but now researchers at Nanjing University in China have developed a polymer nanoparticle that can bind to HER2 just as...
iCAD, a company based in Nashua, New Hampshire, won European CE Mark approval for its ProFound AI for 2D Mammography software system. The product relies on a "high-functioning, deep learning" artificial intelligence algorithm to analyze 2D mammography scans and point out potential areas of concern. The software package provides "Certainty of Finding" and "Case Scores" for each instance of a suspect lesion that it identifies, helping radiologists better focus on what's important while quickening and improving the quality of diagnosis. The system works by noticing slight changes in soft tissue...
INSIGHTEC, an Israeli firm, and GE Healthcare have won FDA approval and the European CE mark for the Exablate Neuro with the SIGNA Premier MRI. The Exablate Neuro, made by INSIGHTEC, delivers focused ultrasound into the brain as a treatment option for tremor dominant Parkinson's disease, essential tremor, and neuropathic pain (the last indication appropriate only to Europe). This gives clinicians the ability to treat patients without penetrating the scalp and brain. The SIGNA Premier MRI, a 3.0 Tesla scanner from GE Healthcare, is used prior to the procedure to...

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Medicine

Low Power Network for Wireless Body Sensors

As wearable devices multiply and gather ever more data about our bodies, the batteries and wireless networks they rely on can become strained. To give wearables a... July 19th, 2019

Cardiology

Low Power Network for Wireless Body Sensors

As wearable devices multiply and gather ever more data about our bodies, the batteries and wireless networks they rely on can become strained. To give wearables a... July 19th, 2019

Surgery

Emergency Medicine

Radiology

Anesthesiology

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