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    <updated>2009-11-06T23:22:58Z</updated>
    <subtitle>Internet journal of emerging medical technologies.</subtitle>
    <generator uri="http://www.sixapart.com/movabletype/">Movable Type 3.2</generator>
 
<entry>
    <title>Newborn Babies Cry With Mother&apos;s Accent</title>
    <link rel="alternate" type="text/html" href="http://www.medgadget.com/archives/2009/11/newborn_babies_cry_with_mothers_accent.html" />
    <link rel="service.edit" type="application/atom+xml" href="http://www.medgadget.com/cgi-bin/mt-atom.cgi/weblog/blog_id=3/entry_id=8604" title="Newborn Babies Cry With Mother's Accent" />
    <id>tag:www.medgadget.com,2009://3.8604</id>
    
    <published>2009-11-06T22:21:57Z</published>
    <updated>2009-11-06T23:22:58Z</updated>
    
    <summary>French and German scientists decided to analyze the crying of newborns from the two countries for differences in intonation. Turns out that German babies have a different &quot;accent&quot; to their cry compared with those from France, which implies that language learning perhaps begins even in the womb. The analysis of crying conducted under the supervision of the psychologist Kathleen Wermke from the ZWES showed that the newborns tended to produce the intonation pattern most typical for their respective mother tongue. The crying patterns of the German infants mostly began loud and high and followed a falling curve while the French infants more often cried with a rising tone. This early sensitivity to features of intonation may later help the infants learn their mother tongue, the researchers say. &quot;When they begin to form their first sounds, they can build on melodic patterns that are already familiar and, in this way, don&apos;t have to start from scratch&quot;, says the neuropsychologist. The evolutionary roots of this behaviour are older than the emergence of spoken language, the researchers believe. &quot;The imitation of melodic patterns developed over millions of years and contributes to the mother-child bond&quot; says Friederici. Press release: Babies with an accent ... Abstract in Current Biology: Newborns&apos; Cry Melody Is Shaped by Their Native Language......</summary>
    <author>
        <name>Michael</name>
        
    </author>
            <category term="in the news..." />
    
    <content type="html" xml:lang="en" xml:base="http://www.medgadget.com/">
        <![CDATA[<p><img class="bside" src="http://www.medgadget.com/archives/img/crybaby.jpg" width="300" height="359" />French and German scientists decided to analyze the crying of newborns from the two countries for differences in intonation.  Turns out that German babies have a different "accent" to their cry compared with those from France, which implies that language learning perhaps begins even in the womb.</p>

<blockquote>The analysis of crying conducted under the supervision of the psychologist Kathleen Wermke from the ZWES showed that the newborns tended to produce the intonation pattern most typical for their respective mother tongue. The crying patterns of the German infants mostly began loud and high and followed a falling curve while the French infants more often cried with a rising tone. This early sensitivity to features of intonation may later help the infants learn their mother tongue, the researchers say. "When they begin to form their first sounds, they can build on melodic patterns that are already familiar and, in this way, don't have to start from scratch", says the neuropsychologist. The evolutionary roots of this behaviour are older than the emergence of spoken language, the researchers believe. "The imitation of melodic patterns developed over millions of years and contributes to the mother-child bond" says Friederici. </blockquote>

<p><strong>Press release:</strong> <a href="http://www.mpg.de/english/illustrationsDocumentation/documentation/pressReleases/2009/pressRelease20091105/index.html" title="Babies with an accent">Babies with an accent ...</a></p>

<p>Abstract in <em>Current Biology</em>: <a href="http://www.cell.com/current-biology/abstract/S0960-9822(09)01824-7" title="Newborns' Cry Melody Is Shaped by Their Native Language">Newborns' Cry Melody Is Shaped by Their Native Language...</a></p>]]>
        
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</entry>
<entry>
    <title>Passive IR Monitoring of Breathing for More Comfortable Sleep Studies</title>
    <link rel="alternate" type="text/html" href="http://www.medgadget.com/archives/2009/11/passive_ir_monitoring_of_breathing_for_more_comfortable_sleep_studies.html" />
    <link rel="service.edit" type="application/atom+xml" href="http://www.medgadget.com/cgi-bin/mt-atom.cgi/weblog/blog_id=3/entry_id=8601" title="Passive IR Monitoring of Breathing for More Comfortable Sleep Studies" />
    <id>tag:www.medgadget.com,2009://3.8601</id>
    
    <published>2009-11-06T21:42:15Z</published>
    <updated>2009-11-06T21:17:16Z</updated>
    
    <summary> A collaboration between researchers from University of Houston and University of Texas Health Science Center has developed a new method to perform sleep studies that minimized the amount of equipment that has to be tethered to the patient. The biggest impediment is the tube placed over the nose that monitors airflow. The researchers created an infrared camera monitoring system that can observe breathing passively and quantify the airflow without any tubes. Here&apos;s an NSF interview with the principal scientists of the study explaining their work: Press release: Computer Science Provides a More Sound Way to Test for Sleep Apnea ... Abstract in Sleep: Thermal Infrared Imaging: A Novel Method to Monitor Airflow During Polysomnography ......</summary>
    <author>
        <name>Michael</name>
        
    </author>
            <category term="Medicine" />
    
    <content type="html" xml:lang="en" xml:base="http://www.medgadget.com/">
        <![CDATA[<p><img class="bcntr" src="http://www.medgadget.com/archives/img/serej.jpg" width="468" height="300" /><br />
A collaboration between researchers from University of Houston and University of Texas Health Science Center has developed a new method to perform sleep studies that minimized the amount of equipment that has to be tethered to the patient.  The biggest impediment is the tube placed over the nose that monitors airflow.  The researchers created an infrared camera monitoring system that can observe breathing passively and quantify the airflow without any tubes.</p>

<p>Here's an NSF interview with the principal scientists of the study explaining their work:</p>

<center><embed src=http://www.nsf.gov/js/video/player.swf width=470 height=264 bgcolor=000000 allowfullscreen=true allowscriptaccess=always flashvars=smoothing=true&controlbar=over&file=sleep.flv&streamer=rtmp://nsfgov.flash.internapcdn.net:1935/nsfgov_vitalstream_com/_definst_/video/&image=http://www.nsf.gov/news/mmg/images/videostill.jpg></embed></center>

<p><strong>Press release:</strong> <a href="http://www.nsf.gov/news/news_summ.jsp?cntn_id=115876" title="Computer Science Provides a More Sound Way to Test for Sleep Apnea">Computer Science Provides a More Sound Way to Test for Sleep Apnea ...</a></p>

<p>Abstract in <em>Sleep</em>: <a href="http://www.journalsleep.org/ViewAbstract.aspx?pid=27626" title="Thermal Infrared Imaging: A Novel Method to Monitor Airflow During Polysomnography">Thermal Infrared Imaging: A Novel Method to Monitor Airflow During Polysomnography ...</a></p>]]>
        
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</entry>
<entry>
    <title>FiatLux Visualize Free Is Now Free for All</title>
    <link rel="alternate" type="text/html" href="http://www.medgadget.com/archives/2009/11/fiatlux_visualize_free_is_now_free_for_all.html" />
    <link rel="service.edit" type="application/atom+xml" href="http://www.medgadget.com/cgi-bin/mt-atom.cgi/weblog/blog_id=3/entry_id=8602" title="FiatLux Visualize Free Is Now Free for All" />
    <id>tag:www.medgadget.com,2009://3.8602</id>
    
    <published>2009-11-06T18:11:12Z</published>
    <updated>2009-11-06T20:32:06Z</updated>
    
    <summary><![CDATA[ Medical visualization software company FiatLux Imaging, Inc., from Redmond, WA, has announced that it is making available for download its FiatLux Visualize&trade; Free application. The software, designed to run on any computer with Windows, is a 2D/3D DICOM viewer for CT and MRI medical data. To learn more about the software, check out the press release, product page, or video clips embedded below....]]></summary>
    <author>
        <name>Michael</name>
        
    </author>
            <category term="Informatics" />
            <category term="Radiology" />
    
    <content type="html" xml:lang="en" xml:base="http://www.medgadget.com/">
        <![CDATA[<p><img class="bcntr" src="http://www.medgadget.com/archives/img/oot323.jpg" width="468" height="411" /><br />
Medical visualization software company <strong>FiatLux Imaging</strong>, Inc., from Redmond, WA, has announced that it is making available for download its <a href="http://www.fiatluximaging.com/index2.htm">FiatLux Visualize&trade; Free</a> application. The software, designed to run on any computer with Windows, is a 2D/3D DICOM viewer for CT and MRI medical data.</p>

<p>To learn more about the software, check out the <a href="http://www.fiatluximaging.com/Press-Release-for-FiatLux-Visualize-Free.htm">press release</a>, <a href="http://www.fiatluximaging.com/index2.htm">product page</a>, or video clips embedded below.</p>

<center><object width="500" height="405"><param name="movie" value="http://www.youtube-nocookie.com/v/dXgyplbuS1o&hl=en&fs=1&rel=0&color1=0x2b405b&color2=0x6b8ab6&hd=1&border=1"></param><param name="allowFullScreen" value="true"></param><param name="allowscriptaccess" value="always"></param><embed src="http://www.youtube-nocookie.com/v/dXgyplbuS1o&hl=en&fs=1&rel=0&color1=0x2b405b&color2=0x6b8ab6&hd=1&border=1" type="application/x-shockwave-flash" allowscriptaccess="always" allowfullscreen="true" width="500" height="405"></embed></object></center>

<center><object width="500" height="405"><param name="movie" value="http://www.youtube-nocookie.com/v/oJ6MAHvS9Jc&hl=en&fs=1&rel=0&color1=0x2b405b&color2=0x6b8ab6&hd=1&border=1"></param><param name="allowFullScreen" value="true"></param><param name="allowscriptaccess" value="always"></param><embed src="http://www.youtube-nocookie.com/v/oJ6MAHvS9Jc&hl=en&fs=1&rel=0&color1=0x2b405b&color2=0x6b8ab6&hd=1&border=1" type="application/x-shockwave-flash" allowscriptaccess="always" allowfullscreen="true" width="500" height="405"></embed></object></center>]]>
        
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    </content>
</entry>
<entry>
    <title>Delivery Method for Iomai&apos;s Transcutaneous Vaccine</title>
    <link rel="alternate" type="text/html" href="http://www.medgadget.com/archives/2009/11/delivery_method_for_iomais_transcutaneous_vaccine.html" />
    <link rel="service.edit" type="application/atom+xml" href="http://www.medgadget.com/cgi-bin/mt-atom.cgi/weblog/blog_id=3/entry_id=8599" title="Delivery Method for Iomai's Transcutaneous Vaccine" />
    <id>tag:www.medgadget.com,2009://3.8599</id>
    
    <published>2009-11-06T15:00:03Z</published>
    <updated>2009-11-06T16:30:09Z</updated>
    
    <summary> We&apos;ve previously covered Iomai Corp&apos;s (now part of Intercell) transcutaneous vaccination technology, with the idea being that if you&apos;re able to vaccinate patients through their skin, you can take advantage of the high density of Langerhans cells in the epidermis to activate an amplified immune response. Also, since transcutaneous vaccination does not involve systemic exposure, you&apos;re able to use more potent immune stimulants. These factors, in addition to it being needle-less, make transcutaneous vaccination an appealing option because you need less vaccine for an equal immune response. Additionally, having the vaccine in this dry, patch form also allows it to last much longer without refrigeration (possibly up to six months). Application of the vaccine, however, first requires you to scrape off some of the keratinized epithelium to gain access to the Langerhans cells. This abrasion needs to be consistent, painless, and easy enough that it could be self-administered. At TEDMED, we&apos;ve heard from IDEO&apos;s CEO Tim Brown, whose design firm was hired to develop the application technique for the transcutaneous vaccine patches. IDEO came up with a band aid looking device with a bulls eye and an attached tab. Pressing at the center and pulling the tab draws an abrasive strip across the skin, as well as leaves an ink mark to show where the vaccine patch should be placed. The application device and patch is also made using only standard processes and materials so they&apos;d be easily manufactured in developing countries. The administration device and patch are currently in phase two clinical trials for pandemic influenza. Product page @ IDEO... Flasback:Immunity That&apos;s More Than Skin Deep......</summary>
    <author>
        <name>Sean Duffy</name>
        <uri>www.medgadget.com</uri>
    </author>
            <category term="Medicine" />
            <category term="Pediatrics" />
            <category term="Public Health" />
    
    <content type="html" xml:lang="en" xml:base="http://www.medgadget.com/">
        <![CDATA[<p><img class = "bside" alt="" src="http://www.medgadget.com/archives/img/32534op1.jpg" width="350" height="341"/> We've previously covered <b>Iomai Corp</b>'s (now part of <b>Intercell</b>) <a href="http://www.medgadget.com/archives/2007/01/vaccination_by.html">transcutaneous vaccination technology</a>, with the idea being that if you're able to vaccinate patients through their skin, you can take advantage of the high density of Langerhans cells in the epidermis to activate an amplified immune response. Also, since transcutaneous vaccination does not involve systemic exposure, you're able to use more potent immune stimulants. These factors, in addition to it being needle-less, make transcutaneous vaccination an appealing option because you need less vaccine for an equal immune response. Additionally, having the vaccine in this dry, patch form also allows it to last much longer without refrigeration (possibly up to six months). </p>

<p><img alt="" class="bside" src="http://www.medgadget.com/archives/img/32534op2.jpg" width="300" height="225" />Application of the vaccine, however, first requires you to scrape off some of the keratinized epithelium to gain access to the Langerhans cells. This abrasion needs to be consistent, painless, and easy enough that it could be self-administered. At TEDMED, we've heard from <b>IDEO's</b> CEO Tim Brown, whose design firm was hired to develop the application technique for the transcutaneous vaccine patches. IDEO came up with a band aid looking device with a bulls eye and an attached tab. Pressing at the center and pulling the tab draws an abrasive strip across the skin, as well as leaves an ink mark to show where the vaccine patch should be placed. The application device and patch is also made using only standard processes and materials so they'd be easily manufactured in developing countries. </p>

<p>The administration device and patch are currently in phase two clinical trials for pandemic influenza. </p>

<p><a href="http://www.ideo.com/work/featured/intercell">Product page</a> @ IDEO...</p>

<p><b>Flasback:</b><a href="http://www.medgadget.com/archives/2007/01/vaccination_by.html">Immunity That's More Than Skin Deep...</a></p>]]>
        
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</entry>
<entry>
    <title>Needle Free Insulin Delivery from PICOSULIN</title>
    <link rel="alternate" type="text/html" href="http://www.medgadget.com/archives/2009/11/needle_free_insulin_delivery_from_picosulin.html" />
    <link rel="service.edit" type="application/atom+xml" href="http://www.medgadget.com/cgi-bin/mt-atom.cgi/weblog/blog_id=3/entry_id=8596" title="Needle Free Insulin Delivery from PICOSULIN" />
    <id>tag:www.medgadget.com,2009://3.8596</id>
    
    <published>2009-11-06T08:41:52Z</published>
    <updated>2009-11-06T19:19:26Z</updated>
    
    <summary><![CDATA[ Amy Tenderich from DiabetesMine spoke with Thierry Navarro, co-founder of PICOSULIN, a Geneva, Switzerland company developing a patch and an insulin pump with an unusually open R&D process. A snippet: "We think differently from the traditional way of keeping R&D secret. We have perfected our technology, and we're disclosing the benefits. Now we want to try to get feedback from all the over world. We're using a website survey to capture input from Europe, Asia and the US, " Thierry says. Here's more about the technology from the product page: The simplicity of the system is based on the use of a plastic micro pump which is connected to an ultra precise mechanical system (patent pending) capable of delivering a bolus of 25nl (0.0025U) that is 20 times more precise than any of the existing competing patches on the market which deliver 500nl (0.05U). What&rsquo;s more, the micro pump uses a volumetric pump mechanism capable of aspirating insulin directly from any type or brand of PenFill cartridge. Performance aside, it has the major advantages of its very small size and modular design: the &ldquo;PicoPatch&rdquo; is a wearable patch only 0.59 inches (15 mm) thick, loaded with a standard PenFill cartridge containing 3ml of insulin. Read the interview with more details at DiabetesMine... Link: PICOSULIN......]]></summary>
    <author>
        <name>Michael</name>
        
    </author>
            <category term="Medicine" />
            <category term="Pediatrics" />
    
    <content type="html" xml:lang="en" xml:base="http://www.medgadget.com/">
        <![CDATA[<p><img class="cntr" src="http://www.medgadget.com/archives/img/pp33423%20copy.jpg" width="468" height="153" /><br />
Amy Tenderich from <em>DiabetesMine</em> spoke with Thierry Navarro, co-founder of <strong>PICOSULIN</strong>,  a Geneva, Switzerland company developing a patch and an insulin pump with an unusually open R&D process.  </p>

<p>A snippet:</p>

<blockquote>"We think differently from the traditional way of keeping R&D secret. We have perfected our technology, and we're disclosing the benefits. Now we want to try to get feedback from all the over world.  We're using a website survey to capture input from Europe, Asia and the US, " Thierry says.</blockquote>

<p>Here's more about the technology from the product page:</p>

<p><img class="bside" src="http://www.medgadget.com/archives/img/pum232.jpg" width="213" height="124" /><blockquote>The simplicity of the system is based on the use of a plastic micro pump which is connected to an ultra precise mechanical system (patent pending) capable of delivering a bolus of 25nl (0.0025U) that is 20 times more precise than any of the existing competing patches on the market which deliver 500nl (0.05U).</p>

<p>What&rsquo;s more, the micro pump uses a volumetric pump mechanism capable of aspirating insulin directly from any type or brand of PenFill cartridge.</p>

<p>Performance aside, it has the major advantages of its very small size and modular design: the &ldquo;PicoPatch&rdquo; is a wearable patch only 0.59 inches (15 mm) thick, loaded with a standard PenFill cartridge containing 3ml of insulin.</blockquote></p>

<p><a href="http://www.diabetesmine.com/2009/11/insulin-patch-pump-co-opens-up-rd.html">Read the interview with more details</a> at <em>DiabetesMine</em>...</p>

<p><strong>Link</strong>: <a href="http://www.picosulin.com/index.html">PICOSULIN...</a></p>]]>
        
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<entry>
    <title>NIMBUS Wound Dressing Gets FDA Nod</title>
    <link rel="alternate" type="text/html" href="http://www.medgadget.com/archives/2009/11/nimbus_wound_dressing_gets_fdas_class_ii_medical_device_classification.html" />
    <link rel="service.edit" type="application/atom+xml" href="http://www.medgadget.com/cgi-bin/mt-atom.cgi/weblog/blog_id=3/entry_id=8598" title="NIMBUS Wound Dressing Gets FDA Nod" />
    <id>tag:www.medgadget.com,2009://3.8598</id>
    
    <published>2009-11-06T08:17:14Z</published>
    <updated>2009-11-06T16:12:51Z</updated>
    
    <summary><![CDATA[Quick-Med Technologies out of Gainesville, Florida got its NIMBUS barrier gauze wound dressing classified as a novel Class II medical device by the FDA: The newly issued guidance pertains to a wound dressing with permanently bound cationic biocide pDADMAC, a key component of the NIMBUS technology and one of the molecular entities covered in nine Quick-Med U.S. patents and patents pending and in 24 foreign counterparts. The guidance document specifies only the cationic biocide polyDADMAC; dressings with other cationic biocides are not within the scope of this guidance. BIOGUARD&trade; dressings, which were introduced in June by Quick-Med licensee Derma Sciences, Inc., are the first wound care products to feature the novel, FDA-cleared NIMBUS technology and subject of the Guidance. The dressings serve as a barrier to infection, kill germs absorbed into the dressing, and provide an optimum wound healing environment. The NIMBUS active agent maintains effectiveness even in the presence of large amounts of proteinaceous exudates. NIMBUS is unique in that it is the only non-leaching antimicrobial wound dressing, which the Company believes is an important distinction; other antimicrobial dressings rely on the release of chemicals to the wound bed that can impede the wound healing process. NIMBUS forms a sterile bacterial barrier that prohibits the transfer of microorganisms into the wound because the microbicidal agent is bound to the dressing. NIMBUS is non-toxic, long-lasting and not blocked by organics such as blood, exudates, urine and perspiration. By its design, NIMBUS poses minimal risk of bacteria developing resistance. Press release: FDA Issues Guidance for Quick-Med Technologies' Exclusive Wound Dressing with pDADMAC ......]]></summary>
    <author>
        <name>Michael</name>
        
    </author>
            <category term="Surgery" />
    
    <content type="html" xml:lang="en" xml:base="http://www.medgadget.com/">
        <![CDATA[<p><img class="bcntr" src="http://www.medgadget.com/archives/img/nimbuderm.jpg" width="468" height="208" /><strong>Quick-Med Technologies</strong> out of Gainesville, Florida got its NIMBUS barrier gauze wound dressing classified as a novel Class II medical device by the FDA:  </p>

<p><img class="bside" src="http://www.medgadget.com/archives/img/nim3434.jpg" width="255" height="207" /><blockquote>The newly issued guidance pertains to a wound dressing with permanently bound cationic biocide pDADMAC, a key component of the NIMBUS technology and one of the molecular entities covered in nine Quick-Med U.S. patents and patents pending and in 24 foreign counterparts. The guidance document specifies only the cationic biocide polyDADMAC; dressings with other cationic biocides are not within the scope of this guidance.</p>

<p>BIOGUARD&trade; dressings, which were introduced in June by Quick-Med licensee Derma Sciences, Inc., are the first wound care products to feature the novel, FDA-cleared NIMBUS technology and subject of the Guidance. The dressings serve as a barrier to infection, kill germs absorbed into the dressing, and provide an optimum wound healing environment. The NIMBUS active agent maintains effectiveness even in the presence of large amounts of proteinaceous exudates.</p>

<p>NIMBUS is unique in that it is the only non-leaching antimicrobial wound dressing, which the Company believes is an important distinction; other antimicrobial dressings rely on the release of chemicals to the wound bed that can impede the wound healing process. NIMBUS forms a sterile bacterial barrier that prohibits the transfer of microorganisms into the wound because the microbicidal agent is bound to the dressing. NIMBUS is non-toxic, long-lasting and not blocked by organics such as blood, exudates, urine and perspiration. By its design, NIMBUS poses minimal risk of bacteria developing resistance.</blockquote></p>

<p><strong>Press release:</strong> <a href="http://www.quickmedtech.com/news-information/news/news-102309.php" title="FDA Issues Guidance for Quick-Med Technologies Exclusive Wound Dressing with pDADMAC">FDA Issues Guidance for Quick-Med Technologies' Exclusive Wound Dressing with pDADMAC ...</a></p>]]>
        
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<entry>
    <title>PET/MR Scanner Development Project on Course</title>
    <link rel="alternate" type="text/html" href="http://www.medgadget.com/archives/2009/11/petmr_scanner_development_project_on_course.html" />
    <link rel="service.edit" type="application/atom+xml" href="http://www.medgadget.com/cgi-bin/mt-atom.cgi/weblog/blog_id=3/entry_id=8600" title="PET/MR Scanner Development Project on Course" />
    <id>tag:www.medgadget.com,2009://3.8600</id>
    
    <published>2009-11-06T08:00:03Z</published>
    <updated>2009-11-06T16:07:40Z</updated>
    
    <summary>Combining PET and MRI scanning into one machine has great potential for comprehensive imaging of the body. Modern gamma ray detectors use vacuum photomultiplier tubes which are sensitive to magnetic fields, so a major goal of the project was to overcome this limitation. Philips, the leader of HYPERImage, the multi-institution European project to create a PET/MR machine, is announcing considerate success toward its goal. The milestone that the HYPERImage team has reached is the development of a functional gamma-ray detector that meets the performance requirements of the latest time-of-flight PET scanners. The new gamma-ray detectors have been designed to be compatible with the strong static and dynamic magnetic fields that would be present in a combined PET/MR scanner. Furthermore, the team has achieved major progress with respect to MRI-based static and dynamic PET attenuation correction. Details of these results are presented at the IEEE Nuclear Science Symposium and Medical Imaging Conference, which takes place on October 25-31 in Orlando, Florida, USA. More about the project from the backgrounder: The technical breakthrough behind the team&apos;s development of an MR-compatible gamma-ray detector is the development of a new solid-state, scalable and compact digital detector technology. This technology is based around silicon photomultiplier arrays that offer the desired sensitivity, energy resolution and timing resolution required for time-of-flight PET measurements, and that feature integrated digital read-out electronics. To increase the effective sensitivity, and to reduce the scan-time and dependence of sensitivity on patient size, the detector has been designed to support time-of-flight PET measurements with extremely short coincidence time resolution. In time-of-flight PET scanners, not only the direction of the gamma ray paths is measured but also the difference in time it takes the pair of gamma rays generated by the PET tracers to reach the detector. This time difference measurement substantially increase the precision with which the tracer can be localized. Time-of-flight measurements increase the effective sensitivity by a factor 10 compared to standard systems. The silicon photomultiplier array&apos;s integrated digital read-out electronics contain a low-jitter and low-power signal acquisition unit. Low power consumption is an essential requirement when preparing the technology for integrated whole body scanning applications. Full story: Philips led HYPERImage project advances research on hybrid PET/MR scanner... HYPERImage Project Background Information... Flashbacks: PET/MRI Combination Might Improve Breast CA Visualization ; Novel Photodetectors Lead to Combination PET/MRI Machines ; UC Davis Develops First Combined PET/MRI Tomograph...</summary>
    <author>
        <name>Michael</name>
        
    </author>
            <category term="Radiology" />
    
    <content type="html" xml:lang="en" xml:base="http://www.medgadget.com/">
        <![CDATA[<p><img class="bside" src="http://www.medgadget.com/archives/img/g343.jpg" width="310" height="329" />Combining PET and MRI scanning into one machine has great potential for comprehensive imaging of the body. Modern gamma ray detectors use vacuum photomultiplier tubes which are sensitive to magnetic fields, so a major goal of the project was to overcome this limitation.  <strong>Philips</strong>, the leader of HYPERImage, the multi-institution European project to create a PET/MR machine, is announcing considerate success toward its goal.</p>

<blockquote>The milestone that the HYPERImage team has reached is the development of a functional gamma-ray detector that meets the performance requirements of the latest time-of-flight PET scanners. The new gamma-ray detectors have been designed to be compatible with the strong static and dynamic magnetic fields that would be present in a combined PET/MR scanner. Furthermore, the team has achieved major progress with respect to MRI-based static and dynamic PET attenuation correction. Details of these results are presented at the IEEE Nuclear Science Symposium and Medical Imaging Conference, which takes place on October 25-31 in Orlando, Florida, USA.</blockquote>

<p>More about the project from the backgrounder:</p>

<blockquote>The technical breakthrough behind the team's development of an MR-compatible gamma-ray detector is the development of a new solid-state, scalable and compact digital detector technology. This technology is based around silicon photomultiplier arrays that offer the desired sensitivity, energy resolution and timing resolution required for time-of-flight PET measurements, and that feature integrated digital read-out electronics.

<p>To increase the effective sensitivity, and to reduce the scan-time and dependence of sensitivity on patient size, the detector has been designed to support time-of-flight PET measurements with extremely short coincidence time resolution. In time-of-flight PET scanners, not only the direction of the gamma ray paths is measured but also the difference in time it takes the pair of gamma rays generated by the PET tracers to reach the detector. This time difference measurement substantially increase the precision with which the tracer can be localized. Time-of-flight measurements increase the effective sensitivity by a factor 10 compared to standard systems.</p>

<p>The silicon photomultiplier array's integrated digital read-out electronics contain a low-jitter and low-power signal acquisition unit. Low power consumption is an essential requirement when preparing the technology for integrated whole body scanning applications.</blockquote></p>

<p><strong>Full story</strong>: <a href="http://www.newscenter.philips.com/main/standard/news/press/2009/200991029_hyperimage.wpd">Philips led HYPERImage project advances research on hybrid PET/MR scanner...</a></p>

<p><a href="http://www.newscenter.philips.com/main/standard/news/backgrounders/2009/20091029_hyperimage_backgrounder.wpd">HYPERImage Project Background Information...</a></p>

<p><strong>Flashbacks:</strong> <a href="http://www.medgadget.com/archives/2009/06/petmri_combination_might_deliver_better_breast_cancer_tissue_visualization.html" title="PET/MRI Combination Might Improve Breast CA Visualization">PET/MRI Combination Might Improve Breast CA Visualization </a>; <a href="http://www.medgadget.com/archives/2008/08/novel_photodetectors_lead_to_combination_petmri_machines.html" title="Novel Photodetectors Lead to Combination PET/MRI Machines">Novel Photodetectors Lead to Combination PET/MRI Machines </a>; </strong> <a href="http://www.medgadget.com/archives/2008/03/uc_davis_develops_first_combined_petmri_tomograph.html" title="UC Davis Develops First Combined PET/MRI Tomograph">UC Davis Develops First Combined PET/MRI Tomograph</a></p>]]>
        
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<entry>
    <title>IdentEvent Seizure Detection Software Gets US OK</title>
    <link rel="alternate" type="text/html" href="http://www.medgadget.com/archives/2009/11/identevent_seizure_detection_software_gets_us_ok.html" />
    <link rel="service.edit" type="application/atom+xml" href="http://www.medgadget.com/cgi-bin/mt-atom.cgi/weblog/blog_id=3/entry_id=8597" title="IdentEvent Seizure Detection Software Gets US OK" />
    <id>tag:www.medgadget.com,2009://3.8597</id>
    
    <published>2009-11-06T08:00:02Z</published>
    <updated>2009-11-06T16:01:04Z</updated>
    
    <summary><![CDATA[Optima Neuroscience (Alachua, FL) has announced that FDA has approved the company's software package that detect seizures from long-term EEG recordings. The development of the IdentEvent&trade; algorithm began at the University of Florida, and the software has now shown an exceptional sensitivity and specificity to detect seizure activity. From the press release: Optima&rsquo;s IdentEvent 510(k) submission was supported by the pivotal clinical trial of its groundbreaking seizure detection technology... In a side by side comparison with the current market-leading product, Optima&rsquo;s clinical performance drastically surpassed the competition by generating 85% less false detections (2 per day v. 13+ per day), while offering comparable sensitivity. &ldquo;IdentEvent&rsquo;s ability to accurately identify seizures will make it the most clinically-useful EEG review software on the market.&rdquo; reports Dr. J. Chris Sackellares, Chief Scientific Officer. &ldquo;Our technology&rsquo;s drastic reduction in false detections will allow the neurologist to focus only on the areas of a recording that are of clinical interest. Given the limited number of subspecialists trained to interpret EEGs, IdentEvent will allow for more efficient and cost-effective diagnosis and management of patients suffering from seizure disorders.&rdquo; Product page: IdentEvent ... Press release: IdentEvent Receives FDA Marketing Clearance......]]></summary>
    <author>
        <name>Michael</name>
        
    </author>
            <category term="Neurology" />
    
    <content type="html" xml:lang="en" xml:base="http://www.medgadget.com/">
        <![CDATA[<p><img class="side" src="http://www.medgadget.com/archives/img/IdentEvent.png" width="170" height="152" /><strong>Optima Neuroscience</strong> (Alachua, FL) has announced that FDA has approved the company's software package that detect seizures from long-term EEG recordings.  The development of the IdentEvent&trade; algorithm began at the University of Florida, and the software has now shown an exceptional sensitivity and specificity to detect seizure activity.</p>

<p>From the press release:</p>

<blockquote>Optima&rsquo;s IdentEvent 510(k) submission was supported by the pivotal clinical trial of its groundbreaking seizure detection technology... In a side by side comparison with the current market-leading product, Optima&rsquo;s clinical performance drastically surpassed the competition by generating 85% less false detections (2 per day v. 13+ per day), while offering comparable sensitivity.

<p>&ldquo;IdentEvent&rsquo;s ability to accurately identify seizures will make it the most clinically-useful EEG review software on the market.&rdquo; reports Dr. J. Chris Sackellares, Chief Scientific Officer. &ldquo;Our technology&rsquo;s drastic reduction in false detections will allow the neurologist to focus only on the areas of a recording that are of clinical interest. Given the limited number of subspecialists trained to interpret EEGs, IdentEvent will allow for more efficient and cost-effective diagnosis and management of patients suffering from seizure disorders.&rdquo;</blockquote></p>

<p><strong>Product page:</strong> <a href="http://www.optimaneuro.com/products.php" title="IdentEvent">IdentEvent ...</a></p>

<p><strong>Press release</strong>: <a href="http://www.optimaneuro.com/news/10162009.pdf">IdentEvent Receives FDA Marketing Clearance...</a></p>]]>
        
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<entry>
    <title>iChemoTracker Keeps Tabs on Your Chemo Regiment</title>
    <link rel="alternate" type="text/html" href="http://www.medgadget.com/archives/2009/11/ichemotracker_keeps_tabs_on_your_chemo_regiment.html" />
    <link rel="service.edit" type="application/atom+xml" href="http://www.medgadget.com/cgi-bin/mt-atom.cgi/weblog/blog_id=3/entry_id=8595" title="iChemoTracker Keeps Tabs on Your Chemo Regiment" />
    <id>tag:www.medgadget.com,2009://3.8595</id>
    
    <published>2009-11-06T08:00:01Z</published>
    <updated>2009-11-06T15:43:32Z</updated>
    
    <summary>Merck has released the iChemoDiary for the iPhone platform, an app designed to help patients monitor their time on chemotherapy. The software allows patient to compile chemo treatments, side effects, and general well being, through a set of criteria, that can be later presented to a healthcare provider. Track your chemotherapy schedule, medication, and treatment plan Record some of the possible side effects from chemotherapy treatments, such as nausea, vomiting, pain, fatigue, change in temperature, lack of appetite, tingling in feet or toes, diarrhea, constipation, and rash Create reports that include chemotherapy, medications, and some of the possible side effects on a daily or weekly basis Share your results and discuss your symptoms with your doctor or nurse so you can have a more accurate and informed discussion Product page: iChemoDiary ......</summary>
    <author>
        <name>Michael</name>
        
    </author>
            <category term="Net News" />
            <category term="Oncology" />
    
    <content type="html" xml:lang="en" xml:base="http://www.medgadget.com/">
        <![CDATA[<p><img class="side" src="http://www.medgadget.com/archives/img/2345r3.jpg" width="266" height="499"/><strong>Merck</strong> has released the iChemoDiary for the iPhone platform, an app designed to help patients monitor their time on chemotherapy.  The software allows patient to compile chemo treatments, side effects, and general well being, through a set of criteria, that can be later presented to a healthcare provider.  </p>

<blockquote><li>Track your chemotherapy schedule, medication, and treatment plan</li>
<li>Record some of the possible side effects from chemotherapy treatments, such as nausea, vomiting, pain, fatigue, change in temperature, lack of appetite, tingling in feet or toes, diarrhea, constipation, and rash</li>
<li>Create reports that include chemotherapy, medications, and some of the possible side effects on a daily or weekly basis</li>
<li>Share your results and discuss your symptoms with your doctor or nurse so you can have a more accurate and informed discussion</li></blockquote>

<p><strong>Product page:</strong> <a href="http://www.emend.com/aprepitant/emend/consumer/tools/track_symptoms.jsp?WT.mc_id=N02G0" title="iChemoDiary">iChemoDiary ...</a></p>]]>
        
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<entry>
    <title>Brainwave Sofa Is Exactly What You Were Thinking</title>
    <link rel="alternate" type="text/html" href="http://www.medgadget.com/archives/2009/11/brainwave_sofa_is_exactly_what_you_were_thinking.html" />
    <link rel="service.edit" type="application/atom+xml" href="http://www.medgadget.com/cgi-bin/mt-atom.cgi/weblog/blog_id=3/entry_id=8593" title="Brainwave Sofa Is Exactly What You Were Thinking" />
    <id>tag:www.medgadget.com,2009://3.8593</id>
    
    <published>2009-11-05T19:27:32Z</published>
    <updated>2009-11-05T22:10:17Z</updated>
    
    <summary> Ever wondered what a piece of furniture formed from raw data extracted from your brain would look like? But of course you have, and so did Lucas Maassen and Dries Verbruggen, the designers of the Brainwave Sofa. Mr. Verbruggen had his brain activity measured while he closed his eyes for 3 seconds. The extracted EEG data was used to create a 3D landscape with the x-axis representing the frequency of brainwave activity in hertz, the y-axis is the percentage of activity, and the z- axis is time. The sofa was then created in its physical form by a five axis computer numerical controlled machine, which creates a three dimensional object out of foam. The sofa will be showcased as part of the Bits n&apos; Pieces design exhibition. Read more from the designers here... (hat tip: Wired)...</summary>
    <author>
        <name>jhbarad</name>
        
    </author>
            <category term="etc." />
    
    <content type="html" xml:lang="en" xml:base="http://www.medgadget.com/">
        <![CDATA[<p><img alt="" class="bcntr" src="http://www.medgadget.com/archives/img/bwave_sofa.jpg" width="454" height="280" /><br />
Ever wondered what a piece of furniture formed from raw data extracted from your brain would look like?  But of course you have, and so did Lucas Maassen and Dries Verbruggen, the designers of the Brainwave Sofa.</p>

<p><img alt="" class="bside" src="http://www.medgadget.com/archives/img/bwavesofawaves.jpg" width="264" height="255" />Mr. Verbruggen had his brain activity measured while he closed his eyes for 3 seconds.  The extracted EEG data was used to create a 3D landscape with the x-axis representing the frequency of brainwave activity in hertz, the y-axis is the percentage of activity, and the z- axis is time.  The sofa was then created in its physical form by a five axis computer numerical controlled machine, which creates a three dimensional object out of foam.</p>

<p>The sofa will be showcased as part of the <a href="http://www.bitsnpiecesnyc.com/pages/exhibit-info">Bits n' Pieces</a> design exhibition.</p>

<p>Read more from the designers <a href="http://www.yatzer.com/1988_brainwave_sofa_by_unfold__lucas_maassen">here</a>...</p>

<p>(hat tip: <a href="http://www.wired.com/wiredscience/2009/11/brainwave-sofa/">Wired)</p>]]>
        
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<entry>
    <title>FDA Panel Recommends Bronchial Thermoplasty Approval for Select Patients</title>
    <link rel="alternate" type="text/html" href="http://www.medgadget.com/archives/2009/11/fda_panel_recommends_bronchial_thermoplasty_for_select_patients.html" />
    <link rel="service.edit" type="application/atom+xml" href="http://www.medgadget.com/cgi-bin/mt-atom.cgi/weblog/blog_id=3/entry_id=8594" title="FDA Panel Recommends Bronchial Thermoplasty Approval for Select Patients" />
    <id>tag:www.medgadget.com,2009://3.8594</id>
    
    <published>2009-11-05T18:10:46Z</published>
    <updated>2009-11-05T18:34:54Z</updated>
    
    <summary><![CDATA[ According to Dow Jones Newswires, an FDA panel has recommended the approval of Alair&reg; bronchial thermoplasty device from Sunnyvale, California based Asthmatx, Inc. Designed to reduce the amount of smooth muscles in the walls of small to medium size airways, the device will likely be indicated for drug-resistant adult cases of severe asthma. We have reported extensively on this technology, including on positive results from the Asthma Intervention Research 2 (AIR2) Trial, a 300 patient strong study reported in May, that has showed reduction in extreme asthma attacks by 32 percent, and 84 percent reduction in emergency room trips in patients s/p treatment. The device--the Alair Bronchial Thermoplasty System--if approved would be the first non-drug treatment approved by the FDA. The product is made by Asthmatx Inc., a closely held firm based in Sunnyvale, Calif., and is designed to be used in adult asthma patients whose disease isn't well controlled on both short- and long-acting medications. Specifically, the panel voted 6 to 1 that the treatment be approved with conditions, including a registry of patients treated to track the long-term safety and effectiveness of the device. The FDA typically follows the advice of its panels but isn't required to. If approved, the device could be on the market during the first half of 2010. The FDA noted that about 22 million Americans have asthma and about 4,000 people die each year &quot;in spite of optimal medical management.&quot; About 500,000 people are hospitalized with asthma exacerbations annually in the U.S. Dow Jones Newswires: FDA Panel Backs Novel Device To Treat Severe Asthma... Technology page: Bronchial Thermoplasty... Flashbacks: Bronchial Thermoplasty Does Well in AIR2 Trial ; The Alair&reg; System for Bronchial Thermoplasty&trade;; Alair System May Become Option for Asthmatics...]]></summary>
    <author>
        <name>Michael</name>
        
    </author>
            <category term="Medicine" />
            <category term="Thoracic Surgery" />
    
    <content type="html" xml:lang="en" xml:base="http://www.medgadget.com/">
        <![CDATA[<p><img class="bcntr" alt="" src="http://www.medgadget.com/archives/img/bronchtherm.jpg"><br />
According to <em>Dow Jones Newswires</em>, an FDA panel has recommended the approval of  Alair&reg; bronchial thermoplasty device from Sunnyvale, California based <strong>Asthmatx</strong>, Inc. Designed to reduce the amount of smooth muscles in the walls of small to medium size airways, the device will likely be indicated for drug-resistant adult cases of severe asthma. We have reported extensively on this technology, including on <a href="http://medgadget.com/archives/2009/05/bronchial_thermoplasty_does_well_in_air2_trial.html" title="positive results from the Asthma Intervention Research 2 (AIR2) Trial">positive results from the Asthma Intervention Research 2 (AIR2) Trial</a>, a 300 patient strong study reported in May, that has showed reduction in extreme asthma attacks by 32 percent, and 84 percent reduction in emergency room trips in patients s/p treatment.</p>

<p><img alt="" class="bside" src="http://www.medgadget.com/archives/img/1324alr.jpg" width="321" height="240" /><blockquote>The device--the Alair Bronchial Thermoplasty System--if approved would be the first non-drug treatment approved by the FDA. The product is made by Asthmatx Inc., a closely held firm based in Sunnyvale, Calif., and is designed to be used in adult asthma patients whose disease isn't well controlled on both short- and long-acting medications.</p>

<p>Specifically, the panel voted 6 to 1 that the treatment be approved with conditions, including a registry of patients treated to track the long-term safety and effectiveness of the device. The FDA typically follows the advice of its panels but isn't required to. If approved, the device could be on the market during the first half of 2010.</p>

<p>The FDA noted that about 22 million Americans have asthma and about 4,000 people die each year &quot;in spite of optimal medical management.&quot; About 500,000 people are hospitalized with asthma exacerbations annually in the U.S. </blockquote></p>

<p><strong>Dow Jones Newswires:</strong> <a href="http://online.wsj.com/article/BT-CO-20091028-719349.html" title="FDA Panel Backs Novel Device To Treat Severe Asthma">FDA Panel Backs Novel Device To Treat Severe Asthma...</a></p>

<p><strong>Technology page:</strong> <a href="http://www.asthmatx.com/canada_eu/medical-professionals/bronchial-thermoplasty-for-doctors.html" title="Bronchial Thermoplasty">Bronchial Thermoplasty...</a></p>

<p><strong>Flashbacks:</strong> <a href="http://www.medgadget.com/archives/2009/05/bronchial_thermoplasty_does_well_in_air2_trial.html" title="Bronchial Thermoplasty Does Well in AIR2 Trial">Bronchial Thermoplasty Does Well in AIR2 Trial </a>; <a href="http://medgadget.com/archives/2006/02/the_alair_syste_1.html" title="The Alair&reg; System for Bronchial Thermoplasty&trade;">The Alair&reg; System for Bronchial Thermoplasty&trade;</a>; <a href="http://medgadget.com/archives/2008/02/alair_system_may_become_option_for_asthmatics.html" title="Alair System May Become Option for Asthmatics">Alair System May Become Option for Asthmatics</a></p>]]>
        
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<br /><a href="http://www.pheedo.com/click.phdo?feedUrl=http%3A//feeds.medgadget.com/Medgadget&amp;itemLink=http%3A%2F%2Fwww.medgadget.com%2Farchives%2F2009%2F11%2Ffda_panel_recommends_bronchial_thermoplasty_for_select_patients.html&amp;itemDate=2009-11-05%2018%3A10%3A46&amp;itemTitle=FDA%20Panel%20Recommends%20Bronchial%20Thermoplasty%20Approval%20for%20Select%20Patients"><img border="0" src="http://www.pheedo.com/img.phdo?feedUrl=http%3A//feeds.medgadget.com/Medgadget&amp;itemLink=http%3A%2F%2Fwww.medgadget.com%2Farchives%2F2009%2F11%2Ffda_panel_recommends_bronchial_thermoplasty_for_select_patients.html&amp;itemDate=2009-11-05%2018%3A10%3A46&amp;itemTitle=FDA%20Panel%20Recommends%20Bronchial%20Thermoplasty%20Approval%20for%20Select%20Patients" /></a>
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    </content>
</entry>
<entry>
    <title>The Ribosome: The Cell&apos;s Protein-Synthesizing Machine and How Antibiotics Disrupt It</title>
    <link rel="alternate" type="text/html" href="http://www.medgadget.com/archives/2009/11/the_ribosome_the_cells_proteinsynthesizing_machine_and_how_antibiotics_disrupt_it.html" />
    <link rel="service.edit" type="application/atom+xml" href="http://www.medgadget.com/cgi-bin/mt-atom.cgi/weblog/blog_id=3/entry_id=8592" title="The Ribosome: The Cell's Protein-Synthesizing Machine and How Antibiotics Disrupt It" />
    <id>tag:www.medgadget.com,2009://3.8592</id>
    
    <published>2009-11-05T17:42:46Z</published>
    <updated>2009-11-05T17:51:32Z</updated>
    
    <summary>Here&apos;s an excerpt from a fascinating lecture presented at Brookhaven National Lab in 2004 by Venkatraman &quot;Venki&quot; Ramakrishnan, the winner of the 2009 Nobel Prize in Chemistry:...</summary>
    <author>
        <name>Michael</name>
        
    </author>
    
    <content type="html" xml:lang="en" xml:base="http://www.medgadget.com/">
        <![CDATA[<p>Here's an excerpt from a fascinating lecture presented at Brookhaven National Lab in 2004 by Venkatraman "Venki" Ramakrishnan, the winner of the 2009 Nobel Prize in Chemistry:</p>

<center><object width="445" height="364"><param name="movie" value="http://www.youtube.com/v/E6wXlpkQVww&hl=en&fs=1&rel=0&color1=0x2b405b&color2=0x6b8ab6&border=1"></param><param name="allowFullScreen" value="true"></param><param name="allowscriptaccess" value="always"></param><embed src="http://www.youtube.com/v/E6wXlpkQVww&hl=en&fs=1&rel=0&color1=0x2b405b&color2=0x6b8ab6&border=1" type="application/x-shockwave-flash" allowscriptaccess="always" allowfullscreen="true" width="445" height="364"></embed></object></center>]]>
        
<![CDATA[
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    </content>
</entry>
<entry>
    <title>Quick and Easy Test for Pesticide Presence in Food and Drinks</title>
    <link rel="alternate" type="text/html" href="http://www.medgadget.com/archives/2009/11/quick_and_easy_test_for_pesticide_presence_in_food_and_drinks.html" />
    <link rel="service.edit" type="application/atom+xml" href="http://www.medgadget.com/cgi-bin/mt-atom.cgi/weblog/blog_id=3/entry_id=8587" title="Quick and Easy Test for Pesticide Presence in Food and Drinks" />
    <id>tag:www.medgadget.com,2009://3.8587</id>
    
    <published>2009-11-05T17:30:43Z</published>
    <updated>2009-11-05T17:38:38Z</updated>
    
    <summary>Scientists from McMaster University in Canada have developed a dipstick that changes color when exposed to organophosphate pesticides. The test provides results in a matter of minutes, is reportedly inexpensive to produce, could be used for food testing, and perhaps might lead to a marketable product that one day could be found in food stores. From the abstract in Analytical Chemistry: A reagentless bioactive paper-based solid-phase biosensor was developed for detection of acetylcholinesterase (AChE) inhibitors, including organophosphate pesticides. The assay strip is composed of a paper support (1 x 10 cm), onto which AChE and a chromogenic substrate, indophenyl acetate (IPA), were entrapped using biocompatible sol-gel derived silica inks in two different zones (e.g., sensing and substrate zones). The assay protocol involves first introducing the sample to the sensing zone via lateral flow of a pesticide-containing solution. Following an incubation period, the opposite end of the paper support is placed into distilled deionized water (ddH2O) to allow lateral flow in the opposite direction to move paper-bound IPA to the sensing area to initiate enzyme catalyzed hydrolysis of the substrate, causing a yellow-to-blue color change. The modified sensor is able to detect pesticides without the use of any external reagents with excellent detection limits (bendiocarb ~ 1 nM; carbaryl ~ 10 nM; paraoxon ~ 1 nM; malathion ~ 10 nM) and rapid response times (5 min). The sensor strip showed negligible matrix effects in detection of pesticides in spiked milk and apple juice samples. Bioactive paper-based assays on pesticide residues collected from food samples showed good agreement with a conventional mass spectrometric assay method. Abstract in Analytical Chemistry: Reagentless Bidirectional Lateral Flow Bioactive Paper Sensors for Detection of Pesticides in Beverage and Food Samples Statement by the American Chemical Society: An inexpensive &apos;dipstick&apos; test for pesticides in foods ......</summary>
    <author>
        <name>Michael</name>
        
    </author>
            <category term="Public Health" />
    
    <content type="html" xml:lang="en" xml:base="http://www.medgadget.com/">
        <![CDATA[<p><img class="bside" src="http://www.medgadget.com/archives/img/tes3jj.jpg" width="300" height="365" />Scientists from McMaster University in Canada have developed a dipstick that changes color when exposed to organophosphate pesticides.  The test provides results in a matter of minutes, is reportedly inexpensive to produce, could be used for food testing, and perhaps might lead to a marketable product that one day could be found in food stores.</p>

<p>From the abstract in Analytical Chemistry:</p>

<blockquote>A reagentless bioactive paper-based solid-phase biosensor was developed for detection of acetylcholinesterase (AChE) inhibitors, including organophosphate pesticides. The assay strip is composed of a paper support (1 x 10 cm), onto which AChE and a chromogenic substrate, indophenyl acetate (IPA), were entrapped using biocompatible sol-gel derived silica inks in two different zones (e.g., sensing and substrate zones). The assay protocol involves first introducing the sample to the sensing zone via lateral flow of a pesticide-containing solution. Following an incubation period, the opposite end of the paper support is placed into distilled deionized water (ddH<sub>2</sub>O) to allow lateral flow in the opposite direction to move paper-bound IPA to the sensing area to initiate enzyme catalyzed hydrolysis of the substrate, causing a yellow-to-blue color change. The modified sensor is able to detect pesticides without the use of any external reagents with excellent detection limits (bendiocarb ~ 1 nM; carbaryl ~ 10 nM; paraoxon ~ 1 nM; malathion ~ 10 nM) and rapid response times (5 min). The sensor strip showed negligible matrix effects in detection of pesticides in spiked milk and apple juice samples. Bioactive paper-based assays on pesticide residues collected from food samples showed good agreement with a conventional mass spectrometric assay method.</blockquote>

<p>Abstract in <em>Analytical Chemistry</em>: <a href="http://pubs.acs.org/stoken/presspac/presspac/full/10.1021/ac901714h?cookieSet=1">Reagentless Bidirectional Lateral Flow Bioactive Paper Sensors for Detection of Pesticides in Beverage and Food Samples</a></p>

<p><strong>Statement by the American Chemical Society:</strong> <a href="http://www.eurekalert.org/pub_releases/2009-11/acs-ai110409.php" title="An inexpensive 'dipstick' test for pesticides in foods">An inexpensive 'dipstick' test for pesticides in foods ...</a></p>]]>
        
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    </content>
</entry>
<entry>
    <title>Reminder: Get Your Sci Fi On</title>
    <link rel="alternate" type="text/html" href="http://www.medgadget.com/archives/2009/11/reminder_get_your_sci_fi_on_3.html" />
    <link rel="service.edit" type="application/atom+xml" href="http://www.medgadget.com/cgi-bin/mt-atom.cgi/weblog/blog_id=3/entry_id=8591" title="Reminder: Get Your Sci Fi On" />
    <id>tag:www.medgadget.com,2009://3.8591</id>
    
    <published>2009-11-05T17:12:21Z</published>
    <updated>2009-11-05T17:19:57Z</updated>
    
    <summary>November 16th is the deadline for our Sci Fi Writing Contest. So go ahead and start typing, and don&apos;t forget to develop some compelling characters and place them in conflict -- one either created or resolved by powerful new directions in medical technology. Along the way, you could tell us something new about ourselves, our values, and our flaws. Send in your submissions to: scifi@medgadget.com....</summary>
    <author>
        <name>Michael</name>
        
    </author>
    
    <content type="html" xml:lang="en" xml:base="http://www.medgadget.com/">
        <![CDATA[<p>November 16th is the deadline for our <a href="http://medgadget.com/archives/2009/11/medgadgets_scifi_writing_contest_return_of_the_prose.html">Sci Fi Writing Contest</a>.</p>

<p>So go ahead and start typing, and don't forget to develop some compelling characters and place them in conflict -- one either created or resolved by powerful new directions in medical technology. Along the way, you could tell us something new about ourselves, our values, and our flaws.</p>

<p>Send in your submissions to: <strong><em>scifi@medgadget.com</em></strong>.</p>]]>
        
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    </content>
</entry>
<entry>
    <title>Freedom Leg Replaces Crutches for Easier Mobility</title>
    <link rel="alternate" type="text/html" href="http://www.medgadget.com/archives/2009/11/freedom_leg_replaces_crutches_for_easier_mobility.html" />
    <link rel="service.edit" type="application/atom+xml" href="http://www.medgadget.com/cgi-bin/mt-atom.cgi/weblog/blog_id=3/entry_id=8588" title="Freedom Leg Replaces Crutches for Easier Mobility" />
    <id>tag:www.medgadget.com,2009://3.8588</id>
    
    <published>2009-11-05T08:39:05Z</published>
    <updated>2009-11-05T14:42:34Z</updated>
    
    <summary> Everyone hates having to use crutches after a leg injury, so a company that started as a bicycle manufacturer and recently evolved into medical mobility products thinks it&apos;s got the answer. The Freedom Leg from Forward Mobility out of Edmonds, Washington transfers the weight of the body to the upper leg, completely relieving the injured area from strain. Made out of composite materials, the device has a weight of only 2.6 pounds (1.2 kilo). Go beyond the limitations of crutches, wheelchairs or scooters. It is truly an off-loading prosthetic that allows the user to fully integrate the device into their lives, giving them complete mobility. The user has the ability to accomplish all their normal day to day tasks without assistance, while at the same time keeping the strength in upper muscles of the injured leg. Product page: Freedom Leg......</summary>
    <author>
        <name>Michael</name>
        
    </author>
            <category term="Orthopedic Surgery" />
            <category term="Rehab" />
    
    <content type="html" xml:lang="en" xml:base="http://www.medgadget.com/">
        <![CDATA[<p><img class="bside" src="http://www.medgadget.com/archives/img/shapeimage_14.png" width="120" height="385" /><br />
Everyone hates having to use crutches after a leg injury, so a company that started as a bicycle manufacturer and recently evolved into medical mobility products thinks it's got the answer.  The Freedom Leg from <strong>Forward Mobility</strong> out of Edmonds, Washington transfers the weight of the body to the upper leg, completely relieving the injured area from strain.  Made out of composite materials, the device has a weight of only  2.6 pounds (1.2 kilo).</p>

<blockquote>Go beyond the limitations of crutches, wheelchairs  or scooters. It is truly an off-loading prosthetic that allows the user to fully integrate the device into their lives, giving them complete mobility. The user has the ability to accomplish all their normal day to day tasks without assistance, while at the same time keeping the strength in upper muscles of the injured leg.
</blockquote>

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<p><strong>Product page</strong>: <a href="http://fwdmobility.com/Freedom_Leg_Off-Loading_Prosthetic.html">Freedom Leg...</a></p>]]>
        
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