<?xml version="1.0" encoding="utf-8"?>
<feed xmlns="http://www.w3.org/2005/Atom">
    <title>Medgadget</title>
    <link rel="alternate" type="text/html" href="http://www.medgadget.com/" />
    <link rel="self" type="application/atom+xml" href="http://www.medgadget.com/atom.xml" />
   <id>tag:www.medgadget.com,2008://3</id>
    <link rel="service.post" type="application/atom+xml" href="http://www.medgadget.com/cgi-bin/mt-atom.cgi/weblog/blog_id=3" title="Medgadget" />
    <updated>2008-05-08T16:45:52Z</updated>
    <subtitle>Internet journal of emerging medical technologies.</subtitle>
    <generator uri="http://www.sixapart.com/movabletype/">Movable Type 3.2</generator>
 
<entry>
    <title>GE Healthcare Unveils New 3.0T Signa MR750 System</title>
    <link rel="alternate" type="text/html" href="http://www.medgadget.com/archives/2008/05/ge_healthcare_unveils_new_30t_signa_mr750_system.html" />
    <link rel="service.edit" type="application/atom+xml" href="http://www.medgadget.com/cgi-bin/mt-atom.cgi/weblog/blog_id=3/entry_id=5875" title="GE Healthcare Unveils New 3.0T Signa MR750 System" />
    <id>tag:www.medgadget.com,2008://3.5875</id>
    
    <published>2008-05-08T08:00:01Z</published>
    <updated>2008-05-08T16:45:52Z</updated>
    
    <summary><![CDATA[ GE Healthcare is introducing a new 3.0 Tesla magnetic resonance scanner, the latest addition to its Signa family of MRI systems, a machine called Signa&reg; MR750 3.0T. The device, newly approved by the FDA, has just been unveiled at the International Society of Magnetic Resonance in Medicine in Toronto, May 3-9. The Signa MR750 features a newly designed RF Transmit system maximizing performance with a 17 percent gain in scanning efficiency. In addition, the system includes the GE-exclusive Optical RF Technology that adds up to 27 percent higher signal-to-noise ratio (SNR) over conventional, non-optical MR receivers by reducing electrical noise and increasing signal detection. When combined with GE&rsquo;s use of high-density surface coils, the optical receive chain is a critical path for ensuring clear signal reception and data analysis. To ensure that the high-density approach will always be maintained, the Signa MR750 3.0T architecture is scalable to 128 channels of simultaneous data acquisition. Revolutionizing imaging capabilities with new parallel imaging technique In efforts to improve full-body imaging on 3.0T MR, GE Healthcare&rsquo;s Signa MR750 features a newly developed parallel imaging technique entitled ARC&trade;, Auto Calibrating Reconstruction for Cartesian imaging. In addition to reducing specific absorption rate (SAR), the ARC technique also improves body imaging by allowing: Auto-calibration that helps avoid collecting external sensitivity map; Less sensitive to field-of-view (FOV) positioning with a tight FOV; Clinically practical reconstruction times for continuous scanning; and Workflow simplification that can be seamlessly integrated into sequences without the need for separate calibration scans. As a result of this new imaging technique, the MR 750 also features new operational efficient advanced applications, including: LAVA-IDEAL&trade; LAVA-IDEAL is a dual-echo acquisition technique that raises the bar on existing sequences to provide consistent, detailed, three-dimensional abdominal images in one breath-hold. By allowing the user to select the output image types-- in-phase, opposed-phase, water and fat-- LAVA-IDEAL has the ability to produce four image contrasts with only one scan. With this new 3.0T application, clinicians can now conduct a complete liver exam in 15 minutes. &ldquo;LAVA-IDEAL is a robust sequence that offers &lsquo;fat only&rsquo; and &lsquo;water only&rsquo; images in addition to excellent in-phase and opposed-phase images in a single breath-hold. This sequence has quickly become a routine part of all our abdominal sequence protocols at 3.0T,&rdquo; said Dr. Elmar Merkle, professor of Radiology, Head of Body Magnetic Resonance Imaging and Medical Director of the Center for Advanced Magnetic Resonance...]]></summary>
    <author>
        <name>Michael</name>
        
    </author>
            <category term="Radiology" />
    
    <content type="html" xml:lang="en" xml:base="http://www.medgadget.com/">
        <![CDATA[<p><img alt="" class="bcntr" src="http://www.medgadget.com/archives/img/6468mr1.jpg" width="450" height="393" /><br />
<strong>GE Healthcare</strong> is introducing a new 3.0 Tesla magnetic resonance scanner, the latest addition to its Signa family of MRI systems, a machine called Signa&reg; MR750 3.0T. The device, newly approved by the FDA, has just been unveiled  at the International Society of Magnetic Resonance in Medicine in Toronto, May 3-9.</p>

<p><img alt="" class="side" src="http://www.medgadget.com/archives/img/6468mr2.jpg" width="230" height="155" /><blockquote>The Signa MR750 features a newly designed RF Transmit system maximizing performance with a 17 percent gain in scanning efficiency. In addition, the system includes the GE-exclusive Optical RF Technology that adds up to 27 percent higher signal-to-noise ratio (SNR) over conventional, non-optical MR receivers by reducing electrical noise and increasing signal detection.</p>

<p>When combined with GE&rsquo;s use of high-density surface coils, the optical receive chain is a critical path for ensuring clear signal reception and data analysis. To ensure that the high-density approach will always be maintained, the Signa MR750 3.0T architecture is scalable to 128 channels of simultaneous data acquisition.</p>

<p>Revolutionizing imaging capabilities with new parallel imaging technique</p>

<p>In efforts to improve full-body imaging on 3.0T MR, GE Healthcare&rsquo;s Signa MR750 features a newly developed parallel imaging technique entitled ARC&trade;, Auto Calibrating Reconstruction for Cartesian imaging.  In addition to reducing specific absorption rate (SAR), the ARC technique also improves body imaging by allowing:</p>

<p><li>Auto-calibration that helps avoid collecting external sensitivity map;</li><br />
<li>Less sensitive to field-of-view (FOV) positioning with a tight FOV;</li><br />
<li>Clinically practical reconstruction times for continuous scanning; and</li><br />
<li>Workflow simplification that can be seamlessly integrated into sequences without the need for separate calibration scans.</li></p>

<p>As a result of this new imaging technique, the MR 750 also features new operational efficient advanced applications, including:</p>

<p>LAVA-IDEAL&trade;<br />
LAVA-IDEAL is a dual-echo acquisition technique that raises the bar on existing sequences to provide consistent, detailed, three-dimensional abdominal images in one breath-hold. By allowing the user to select the output image types-- in-phase, opposed-phase, water and fat-- LAVA-IDEAL has the ability to produce four image contrasts with only one scan.  With this new 3.0T application, clinicians can now conduct a complete liver exam in 15 minutes.</p>

<p>&ldquo;LAVA-IDEAL is a robust sequence that offers &lsquo;fat only&rsquo; and &lsquo;water only&rsquo; images in addition to excellent in-phase and opposed-phase images in a single breath-hold. This sequence has quickly become a routine part of all our abdominal sequence protocols at 3.0T,&rdquo; said Dr. Elmar Merkle, professor of Radiology, Head of Body Magnetic Resonance Imaging and Medical Director of the Center for Advanced Magnetic Resonance Development at Duke University.</p>

<p>VIBRANT-IDEAL&trade;<br />
VIBRANT-IDEAL is a new application that allows for fat-free breast imaging with high spatio-temporal resolution.  This application catches the shortest in- and out-of phase echoes to keep scan times comparable to single echo acquisitions even though twice the amount of data is collected.</p>

<p>VIBRANT-IDEAL optimizes acquisition with a high signal-to-noise ratio (SNR ) for acquiring high quality water and fat images. This capability lets the user prescribe thinner slices for high spatial resolution imaging.</p>

<p>PROPELLER 2.0&trade;<br />
PROPELLER 2.0 enables strong performance in all neuro  imaging planes with the implementation of the No Phase Wrap (NPW) technique. NPW allows virtually ghost-artifact-free, motion-immune scans in sagittal, coronal, axial and oblique planes. Since this technique effectively deals with the aliasing artifact, PROPELLER 2.0 is now more robust performing small field-of-view (FOV) scans.</blockquote><br />
<img alt="" class="bcntr" src="http://www.medgadget.com/archives/img/6468mr3.jpg" width="460" height="193" /><br />
<blockquote>Driven by customer demands for improved clinical capabilities, the Signa MR750 has been designed around clinical workflow needs with a strong focus on improving productivity, With that in mind, the system also includes operational efficiencies such as the newly designed detachable patient table and the first ever in-room operator console.</p>

<p>In addition, The Signa MR750 features automated acquisition based on the concept of touch and go protocols. The aspect of the system allows for more focused attention on the patient and consistent protocols and processing across operating technicians.</blockquote></p>

<p><strong>Product page:</strong> <a href="http://www.gehealthcare.com/usen/mr/products/mr750.html" title="Signa MR750">Signa MR750...</a></p>

<p><a href="http://pressroom.gehealthcare.com/proom/internet/NewsandEvents.jsp?release_id=14325">Press release...</a></p>]]>
        
    </content>
</entry>
<entry>
    <title>Boston Scientific ALTREA Pacemaker EU Approved</title>
    <link rel="alternate" type="text/html" href="http://www.medgadget.com/archives/2008/05/post_29.html" />
    <link rel="service.edit" type="application/atom+xml" href="http://www.medgadget.com/cgi-bin/mt-atom.cgi/weblog/blog_id=3/entry_id=5873" title="Boston Scientific ALTREA Pacemaker EU Approved" />
    <id>tag:www.medgadget.com,2008://3.5873</id>
    
    <published>2008-05-07T19:07:50Z</published>
    <updated>2008-05-07T19:49:44Z</updated>
    
    <summary>Boston Scientific just received approval from the EU to market the company&apos;s newest family of pacemakers. The following features are listed in the press release: ALTRUA is Boston Scientific&apos;s most advanced pacemaker and delivers enhanced therapies while maintaining its small size and battery longevity. It is the first Boston Scientific-branded pacemaker to treat bradycardia, a condition in which the heart beats too slowly -- usually less than 60 beats per minute -- depriving the body of sufficient oxygen. Multiple Atrial Ventricular (AV) Delay programming options: These options are designed to reduce unnecessary right ventricular (RV) pacing, without dropping ventricular beats, a key distinction from other competitive RV pacing algorithms. The ALTRUA 50 and 60 series also include an enhanced AV search hysteresis feature, now with an extendable AV delay out to 400 milliseconds, providing physicians with additional flexibility to tailor device programming for unique patient needs. Minute Ventilation (MV) Blended Sensor: This proprietary technology treats a condition called Chronotropic Incompetence, which is the inability of the heart to regulate its rate appropriately in response to physical activity and emotional stress. Boston Scientific&apos;s MV Blended sensor is the only sensor that has been shown to restore Chronotropic Competence. Ventricular Rate Regulation (VRR): This feature helps physicians manage patients with frequent atrial arrythmias. Automatic Capture: This capability is designed to offer automatic, safe and accurate ventricular pulse management. The device checks every heart beat to see if the lower chambers of the heart contract in response to the delivered pulse. If no contraction is detected, a backup pace with more energy is delivered. News release: Boston Scientific Announces European Approval and Market Launch of New Family of Advanced Pacemakers...</summary>
    <author>
        <name>Michael</name>
        
    </author>
            <category term="Cardiac Surgery" />
            <category term="Cardiology" />
            <category term="Radiology" />
    
    <content type="html" xml:lang="en" xml:base="http://www.medgadget.com/">
        <![CDATA[<p><img class="side" src="http://www.medgadget.com/archives/img/ALTRUA_60.jpg" width="300" height="314" /><strong>Boston Scientific</strong> just received approval from the EU to market the company's newest  family of pacemakers.</p>

<p>The following features are listed in the press release:</p>

<blockquote>ALTRUA is Boston Scientific's most advanced pacemaker and delivers enhanced therapies while maintaining its small size and battery longevity. It is the first Boston Scientific-branded pacemaker to treat bradycardia, a condition in which the heart beats too slowly -- usually less than 60 beats per minute -- depriving the body of sufficient oxygen.

<p><li>Multiple Atrial Ventricular (AV) Delay programming options: These options are designed to reduce unnecessary right ventricular (RV) pacing, without dropping ventricular beats, a key distinction from other competitive RV pacing algorithms.  The ALTRUA 50 and 60 series also include an enhanced AV search hysteresis feature, now with an extendable AV delay out to 400 milliseconds, providing physicians with additional flexibility to tailor device programming for unique patient needs.</li></p>

<p><li>Minute Ventilation (MV) Blended Sensor: This proprietary technology treats a condition called Chronotropic Incompetence, which is the inability of the heart to regulate its rate appropriately in response to physical activity and emotional stress.  Boston Scientific's MV Blended sensor is the only sensor that has been shown to restore Chronotropic Competence.</li></p>

<p><li>Ventricular Rate Regulation (VRR): This feature helps physicians manage patients with frequent atrial arrythmias.</li></p>

<p><li>Automatic Capture: This capability is designed to offer automatic, safe and accurate ventricular pulse management.  The device checks every heart beat to see if the lower chambers of the heart contract in response to the delivered pulse.  If no contraction is detected, a backup pace with more energy is delivered.</li></blockquote></p>

<p><strong>News release:</strong> <a href="http://bostonscientific.mediaroom.com/index.php?s=43&item=738">Boston Scientific Announces European Approval and Market Launch of New Family of Advanced Pacemakers</a></p>]]>
        
    </content>
</entry>
<entry>
    <title>A Note on Medical Pixie Dust</title>
    <link rel="alternate" type="text/html" href="http://www.medgadget.com/archives/2008/05/a_note_on_medical_pixie_dust.html" />
    <link rel="service.edit" type="application/atom+xml" href="http://www.medgadget.com/cgi-bin/mt-atom.cgi/weblog/blog_id=3/entry_id=5874" title="A Note on Medical Pixie Dust" />
    <id>tag:www.medgadget.com,2008://3.5874</id>
    
    <published>2008-05-07T18:15:25Z</published>
    <updated>2008-05-07T19:31:39Z</updated>
    
    <summary>Yesterday we published a story about a man who re-grew a tip of his finger using &quot;pixie-dust&quot; supposedly sent to him by his brother who worked in a regenerative medicine lab. By now the story has largely been discredited. In our defense, when we saw the story on BBC and other respectful outlets, we did not publish it right away. We sat on it for 5 days or so, awaiting a press release from the University of Pittsburgh. When it did not materialize, without realizing that the story has been discredited, we went ahead and published it. We apologize for this gaffe. More from the BBC... (thanks, Matt!)...</summary>
    <author>
        <name>Michael</name>
        
    </author>
    
    <content type="html" xml:lang="en" xml:base="http://www.medgadget.com/">
        <![CDATA[<p>Yesterday we published a <a href="http://www.medgadget.com/archives/2008/05/medical_pixie_dust_is_it_finally_here.html">story</a> about a man who re-grew a tip of his finger using "pixie-dust" supposedly sent to him by his brother who worked in a regenerative medicine lab. By now the story has largely been <a href="http://www.guardian.co.uk/science/2008/may/03/medicalresearch.health">discredited</a>. In our defense, when we saw the story on <em>BBC</em> and other respectful outlets, we did not publish it right away. We sat on it for 5 days or so, awaiting a press release from the University of Pittsburgh. When it did not materialize, without realizing that the story has been discredited, we went ahead and published it. We apologize for this gaffe.</p>

<p><a href="http://news.bbc.co.uk/2/hi/health/7379745.stm">More</a> from the <em>BBC</em>...</p>

<p>(thanks, <a href="http://iq9.com/blog">Matt</a>!)</p>]]>
        
    </content>
</entry>
<entry>
    <title>Peak PlasmaBlade Wants to Be The New Bovie</title>
    <link rel="alternate" type="text/html" href="http://www.medgadget.com/archives/2008/05/peak_plasmablade.html" />
    <link rel="service.edit" type="application/atom+xml" href="http://www.medgadget.com/cgi-bin/mt-atom.cgi/weblog/blog_id=3/entry_id=5870" title="Peak PlasmaBlade Wants to Be The New Bovie" />
    <id>tag:www.medgadget.com,2008://3.5870</id>
    
    <published>2008-05-07T18:07:53Z</published>
    <updated>2008-05-07T21:41:25Z</updated>
    
    <summary><![CDATA[ PEAK Surgical, Inc. from Palo Alto, CA hates the bovie cutter/coagulator. The company cannot stand the 1920's technology behind the bovie, and how its thermal function destroys healthy patient tissue around the cut. What do we hate about the bovie? Well, you know: all those bovie induced burns and destroyed gloves that surgeons are regularly subjected to. Long story short, PEAK Surgical wants its Peak PlasmaBlade, a cold cutter and coagulator, to be the bovie of the 21st century. The company is quite hopeful: a new study presented in a poster session at the ongoing American College of Obstetricians and Gynecologists' (ACOG) 56th Annual Clinical Meeting in New Orleans showed that PEAK PlasmaBlade&trade; "cut freshly excised human abdominal tissue with little thermal tissue injury compared with traditional electrosurgery." More about the technology: Electrosurgery was invented in the beginning of the 20th century and became one of the most-often used surgical tools after William Bovie introduced his electrosurgery (radiofrequency) generator in 1926. Since then, electrosurgical cutting has been performed using continuous radiofrequency waveforms, which thermally vaporizes soft tissue via an electrical arc through air and Joule heating. This results in a cutting and coagulation action that leaves a wide zone of collateral thermal damage. By contrast, PEAK Surgical&rsquo;s PULSAR Generator supplies pulsed waveforms that produce short plasma-mediated, highly controlled electrical discharges through extensively insulated electrodes on a handheld device -- the PEAK PlasmaBlade. Because the radiofrequency is provided in short pulses with low duty cycle (fraction of time the voltage is ON), and the PEAK PlasmaBlade is so highly insulated, heat diffusion and associated thermal damage to surrounding tissues is limited, resulting in greatly reduced collateral damage and extreme cutting precision. PEAK Surgical&rsquo;s technology including the pulsed plasma-mediated discharges and electrode insulation techniques were originally developed by Professor Daniel Palanker&rsquo;s group at the Hansen Experimental Physics Laboratory and Department of Ophthalmology at Stanford University. They have been evaluated in ophthalmic applications, including human studies in retinal and cataract surgery &ndash; one of the most delicate, precise and difficult types of surgery, and in preclinical studies. Check out the following product brochure distributed by PEAK Surgical: PeakBrochure - Upload a doc Read this doc on Scribd: PeakBrochure Product page: Peak PlasmaBlade... Press release: PEAK Surgical Announces Positive Results from Preclinical Study of PEAK PlasmaBlade&trade; for Obstetric and Gynecologic Surgery Video demonstrating the device......]]></summary>
    <author>
        <name>Michael</name>
        
    </author>
            <category term="Cardiac Surgery" />
            <category term="Neurological Surgery" />
            <category term="Ob/Gyn" />
            <category term="Orthopedic Surgery" />
            <category term="Plastic Surgery" />
            <category term="Surgery" />
            <category term="Thoracic Surgery" />
            <category term="Urology" />
            <category term="Vascular Surgery" />
    
    <content type="html" xml:lang="en" xml:base="http://www.medgadget.com/">
        <![CDATA[<p><img alt="" class="bcntr" src="http://www.medgadget.com/archives/img/3533pl1.jpg" width="468" height="193" /><br />
<strong>PEAK Surgical</strong>, Inc. from Palo Alto, CA hates the bovie cutter/coagulator. The company cannot stand the 1920's technology behind the bovie, and how its thermal function destroys healthy patient tissue around the cut. What do we hate about the bovie? Well, you know: all those bovie induced burns and destroyed gloves that surgeons are regularly subjected to.</p>

<p>Long story short, PEAK Surgical wants its Peak PlasmaBlade, a cold cutter and coagulator, to be the bovie of the 21st century. The company is quite hopeful: a new study presented in a poster session at the ongoing American College of Obstetricians and Gynecologists' (ACOG) 56th Annual Clinical Meeting in New Orleans showed that PEAK PlasmaBlade&trade; "cut freshly excised human abdominal tissue with little thermal tissue injury compared with traditional electrosurgery."</p>

<p>More about the technology:</p>

<blockquote>Electrosurgery was invented in the beginning of the 20th century and became one of the most-often used surgical tools after William Bovie introduced his electrosurgery (radiofrequency) generator in 1926. Since then, electrosurgical cutting has been performed using continuous radiofrequency waveforms, which thermally vaporizes soft tissue via an electrical arc through air and Joule heating. This results in a cutting and coagulation action that leaves a wide zone of collateral thermal damage.

<p>By contrast, PEAK Surgical&rsquo;s PULSAR Generator supplies pulsed waveforms that produce short plasma-mediated, highly controlled electrical discharges through extensively insulated electrodes on a handheld device -- the PEAK PlasmaBlade. Because the radiofrequency is provided in short pulses with low duty cycle (fraction of time the voltage is ON), and the PEAK PlasmaBlade is so highly insulated, heat diffusion and associated thermal damage to surrounding tissues is limited, resulting in greatly reduced collateral damage and extreme cutting precision.</p>

<p>PEAK Surgical&rsquo;s technology including the pulsed plasma-mediated discharges and electrode insulation techniques were originally developed by Professor Daniel Palanker&rsquo;s group at the Hansen Experimental Physics Laboratory and Department of Ophthalmology at Stanford University. They have been evaluated in ophthalmic applications, including human studies in retinal and cataract surgery &ndash; one of the most delicate, precise and difficult types of surgery, and in preclinical studies.</blockquote></p>

<p>Check out the following product brochure distributed by PEAK Surgical:</p>

<center><object codebase="http://download.macromedia.com/pub/shockwave/cabs/flash/swflash.cab#version=9,0,0,0" id="-698214008" name="-698214008" classid="clsid:d27cdb6e-ae6d-11cf-96b8-444553540000" align="middle" height="500" width="468"> <param name="movie" value="http://documents.scribd.com/ScribdViewer.swf?document_id=2903542&access_key=key-2m5fsf4xacl9dwdssmdg&page=1&version=1"> <param name="quality" value="high"> <param name="play" value="true"> <param name="loop" value="true"> <param name="scale" value="showall"> <param name="wmode" value="opaque"> <param name="devicefont" value="false"> <param name="bgcolor" value="#ffffff"> <param name="menu" value="true"> <param name="allowFullScreen" value="true"> <param name="allowScriptAccess" value="always"> <param name="salign" value=""> <embed src="http://documents.scribd.com/ScribdViewer.swf?document_id=2903542&access_key=key-2m5fsf4xacl9dwdssmdg&page=1&version=1" quality="high" pluginspage="http://www.macromedia.com/go/getflashplayer" play="true" loop="true" scale="showall" wmode="opaque" devicefont="false" bgcolor="#ffffff" name="-698214008_object" menu="true" allowfullscreen="true" allowscriptaccess="always" salign="" type="application/x-shockwave-flash" align="middle" height="500" width="468"></embed> </object><div style="font-size:10px;text-align:center;width:468"><a href="http://www.scribd.com/doc/2903542/PeakBrochure">PeakBrochure</a> - <a href="http://www.scribd.com/upload">Upload a doc</a></div><div style="display:none"> Read this doc on Scribd: <a href="http://www.scribd.com/doc/2903542/PeakBrochure">PeakBrochure</a> </div> </center>

<p><strong>Product page:</strong> <a href="http://peak.odacms.com/products/plasmablades/">Peak PlasmaBlade</a>...</p>

<p><strong>Press release:</strong> <a href="http://peak.odacms.com/news/press-releases/index.cfm?i=135">PEAK Surgical Announces Positive Results from Preclinical Study of PEAK PlasmaBlade&trade; for Obstetric and Gynecologic Surgery</a></p>

<p><a href="http://peak.odacms.com/video/plasmablade.cfm">Video demonstrating the device</a>...</p>]]>
        
    </content>
</entry>
<entry>
    <title>HYDROCHALARONE MRI Contrast Agent Does Well in Early Study</title>
    <link rel="alternate" type="text/html" href="http://www.medgadget.com/archives/2008/05/hydrochalarone_mri_contrast_agent_does_well_in_early_study.html" />
    <link rel="service.edit" type="application/atom+xml" href="http://www.medgadget.com/cgi-bin/mt-atom.cgi/weblog/blog_id=3/entry_id=5872" title="HYDROCHALARONE MRI Contrast Agent Does Well in Early Study" />
    <id>tag:www.medgadget.com,2008://3.5872</id>
    
    <published>2008-05-07T18:06:51Z</published>
    <updated>2008-05-07T18:48:50Z</updated>
    
    <summary><![CDATA[HYDROCHALARONE&trade; nanomaterial is a next generation contrast agent, under development by Roanoke, Virginia based firm Luna Innovations, that has just been successfully demonstrated as an effective MRI image enhancer in the mouse model. HYDROCHALARONE is based on the company's proprietary TRIMETASPHERE&reg; molecular cage construct (second picture below), a molecule formed by up to 80 carbon atoms, that is capable of encapsulating a variety of metals (Scandium, Lutetium, Holmium, Gadolinium) inside its cage. From the press statement by Luna Innovations: The new class of molecules discovered by Luna is called HYDROCHALARONE(TM) ( hi-dro-kal-a-rone )-- Hydro, meaning water, combined with Chalaro, the Greek word for relax. The level of relaxivity is the characteristic of molecules that provides the image enhancement. "The high relaxivity in Hydrochalarone means fewer molecules are needed to obtain a better quality image," said Robert Lenk, President of Luna's nanoWorks division. "Our studies demonstrate that our proprietary nanomaterials do not release gadolinium under conditions which are found in the human body. Our imaging studies in mice have shown Hydrochalarone improves image quality up to 30 minutes after injection at a dose 20 times lower than that used with current agents." "Achieving high magnetic resonance relaxivity with a small, biologically inert, chemical moiety that can be derivatized for targeted tissue delivery, cell tracking, or inclusion as part of a nanoparticle drug delivery vehicle is a Holy Grail within the fast evolving field of biomarker development," said Dr. Joseph Ackerman renowned MRI researcher and Chemistry Department Chairman at Washington University in St. Louis. "The design and production of Hydrochalarones by scientists at Luna nanoWorks may herald such an advance." Luna's HYDROCHALARONE(TM) was selected for preclinical studies and a collaboration with National Cancer Institute's Nanotechnology Characterization Laboratory (NCL). "We hope within 12 months the NCL will provide us a complete preclinical package which will contribute to an Investigational New Drug application," said Lenk. "The end goal of Luna's product development effort with the Hydrochalarone is using it as a fundamental building block that will generate a portfolio of novel imaging agents targeted to reveal diagnostic information specific for a variety of different diseases, such as cancer tumors, sites of inflammation and plaque related to coronary artery diseases, as announced in our previous press release." Product page: Luna's HYDROCHALARONE... Press release: Luna Innovations Successfully Demonstrates MRI Contrast Agent......]]></summary>
    <author>
        <name>Michael</name>
        
    </author>
            <category term="Nanomedicine" />
            <category term="Radiology" />
    
    <content type="html" xml:lang="en" xml:base="http://www.medgadget.com/">
        <![CDATA[<p><img alt="" class="bside" src="http://www.medgadget.com/archives/img/7657nyd.jpg" width="300" height="203" />HYDROCHALARONE&trade; nanomaterial is a next generation contrast agent, under development by Roanoke, Virginia based firm <strong>Luna Innovations</strong>, that has just been successfully demonstrated as an effective MRI image enhancer in the mouse model. HYDROCHALARONE is based on the company's proprietary TRIMETASPHERE&reg; molecular cage construct (second picture below), a molecule formed by up to 80 carbon atoms, that is capable of encapsulating a variety of metals (Scandium, Lutetium, Holmium, Gadolinium) inside its cage.</p>

<p>From the press statement by Luna Innovations:</p>

<blockquote>The new class of molecules discovered by Luna is called HYDROCHALARONE(TM) ( hi-dro-kal-a-rone )-- Hydro, meaning water, combined with Chalaro, the Greek word for relax. The level of relaxivity is the characteristic of molecules that provides the image enhancement. "The high relaxivity in Hydrochalarone means fewer molecules are needed to obtain a better quality image," said Robert Lenk, President of Luna's nanoWorks division. "Our studies demonstrate that our proprietary nanomaterials do not release gadolinium under conditions which are found in the human body. Our imaging studies in mice have shown Hydrochalarone improves image quality up to 30 minutes after injection at a dose 20 times lower than that used with current agents."

<p><img alt="" class="bside" src="http://www.medgadget.com/archives/img/Trimetasphere.jpg" width="250" height="239" />"Achieving high magnetic resonance relaxivity with a small, biologically inert, chemical moiety that can be derivatized for targeted tissue delivery, cell tracking, or inclusion as part of a nanoparticle drug delivery vehicle is a Holy Grail within the fast evolving field of biomarker development," said Dr. Joseph Ackerman renowned MRI researcher and Chemistry Department Chairman at Washington University in St. Louis. "The design and production of Hydrochalarones by scientists at Luna nanoWorks may herald such an advance."</blockquote></p>

<p><img class="bside" src="http://www.medgadget.com/archives/img/5344hyd.jpg" width="280" height="231" /><blockquote>Luna's HYDROCHALARONE(TM) was selected for preclinical studies and a collaboration with National Cancer Institute's Nanotechnology Characterization Laboratory (NCL). "We hope within 12 months the NCL will provide us a complete preclinical package which will contribute to an Investigational New Drug application," said Lenk. "The end goal of Luna's product development effort with the Hydrochalarone is using it as a fundamental building block that will generate a portfolio of novel imaging agents targeted to reveal diagnostic information specific for a variety of different diseases, such as cancer tumors, sites of inflammation and plaque related to coronary artery diseases, as announced in our previous press release."</blockquote></p>

<p><strong>Product page:</strong> <a href="http://www.lunananoworks.com/products/trimetaspheres.asp" title="Luna's HYDROCHALARONE">Luna's HYDROCHALARONE...</a></p>

<p><strong>Press release:</strong> <a href="http://ir.lunainnovations.com/phoenix.zhtml?c=196907&p=irol-newsArticle2&ID=1137269&highlight=" title="Luna Innovations Successfully Demonstrates MRI Contrast Agent">Luna Innovations Successfully Demonstrates MRI Contrast Agent...</a></p>]]>
        
    </content>
</entry>
<entry>
    <title>In the Works: Inhalable Drug Testing Device</title>
    <link rel="alternate" type="text/html" href="http://www.medgadget.com/archives/2008/05/in_the_works_inhalable_drug_testing_device.html" />
    <link rel="service.edit" type="application/atom+xml" href="http://www.medgadget.com/cgi-bin/mt-atom.cgi/weblog/blog_id=3/entry_id=5869" title="In the Works: Inhalable Drug Testing Device" />
    <id>tag:www.medgadget.com,2008://3.5869</id>
    
    <published>2008-05-07T17:28:42Z</published>
    <updated>2008-05-07T17:39:55Z</updated>
    
    <summary><![CDATA[ Cambridge Consultants is reporting that the company is developing "a low-cost, portable instrument that has the potential to revolutionise [sic] the way certain drug delivery devices are tested." From the press release: Through the innovative use of technology, the new device can mirror the performance and level of data provided by current laboratory laser diffraction measurement machines, for an estimated one-hundredth of the cost when integrated into a high volume device. The device measures the droplet size distribution in an airstream, a technique used in testing respiratory drug delivery devices. Airborne drug delivery for deep-lung treatment relies on generating particles of a very specific size - too large and the drug never reaches the deep lung, too small and the drug is exhaled and is similarly ineffective. Methods for accurately measuring particle size are very much laboratory-based, for instance the Anderson Cascade method, which is laborious and can slow the development of devices, and the current generation of large laser diffraction measurement devices, which have high initial costs and require a lot of space and skill to operate. By applying its established expertise in optical systems, electronic signal processing and advanced capabilities in the Mie scattering mathematical theory &ndash; a critical element of this form of droplet analysis - Cambridge Consultants has started developing a test unit which could be manufactured in volume for just a few hundred pounds - less than one-hundredth of the cost of a full laboratory laser diffraction installation, the only real solution to such measurements today. It is also small enough to be highly portable, so it would be ideal at clinical drug delivery trials, where it is critical to establish how much drug reaches the patient&rsquo;s deep lung so that doses can be accurately compared to the patient&rsquo;s response. It would also be useful during end-of-line production testing of drug delivery devices... The Cambridge Consultants device is based on low-cost LED components, considerably simplified optical configurations and the application of modern signal processing. It is designed to be robust, portable and simple enough to potentially be operated by semi-skilled clinicians, with standard IT equipment to produce highly accurate plots that indicate the number of droplets within a pre-selected range of sizes. Drugs can therefore be tested at the point of delivery, during clinical trials for example, to ensure doses are delivered as intended by the drug developer. Full story: Breakthrough instrument to test...]]></summary>
    <author>
        <name>Michael</name>
        
    </author>
            <category term="Diagnostics" />
    
    <content type="html" xml:lang="en" xml:base="http://www.medgadget.com/">
        <![CDATA[<p><img alt="" class="bcntr" src="http://www.medgadget.com/archives/img/64743cam.jpg" width="450" height="360" /><br />
<strong>Cambridge Consultants</strong> is reporting that the company is developing "a low-cost, portable instrument that has the potential to revolutionise [sic] the way certain drug delivery devices are tested."</p>

<p>From the press release:</p>

<blockquote>Through the innovative use of technology, the new device can mirror the performance and level of data provided by current laboratory laser diffraction measurement machines, for an estimated one-hundredth of the cost when integrated into a high volume device.  The device measures the droplet size distribution in an airstream, a technique used in testing respiratory drug delivery devices.

<p>Airborne drug delivery for deep-lung treatment relies on generating particles of a very specific size - too large and the drug never reaches the deep lung, too small and the drug is exhaled and is similarly ineffective.  Methods for accurately measuring particle size are very much laboratory-based, for instance the Anderson Cascade method, which is laborious and can slow the development of devices, and the current generation of large laser diffraction measurement devices, which have high initial costs and require a lot of space and skill to operate. </p>

<p>By applying its established expertise in optical systems, electronic signal processing and advanced capabilities in the Mie scattering mathematical theory &ndash; a critical element of this form of droplet analysis - Cambridge Consultants has started developing a test unit which could be manufactured in volume for just a few hundred pounds - less than one-hundredth of the cost of a full laboratory laser diffraction installation, the only real solution to such measurements today.</p>

<p>It is also small enough to be highly portable, so it would be ideal at clinical drug delivery trials, where it is critical to establish how much drug reaches the patient&rsquo;s deep lung so that doses can be accurately compared to the patient&rsquo;s response. It would also be useful during end-of-line production testing of drug delivery devices...</p>

<p>The Cambridge Consultants device is based on low-cost LED components, considerably simplified optical configurations and the application of modern signal processing.  It is designed to be robust, portable and simple enough to potentially be operated by semi-skilled clinicians, with standard IT equipment to produce highly accurate plots that indicate the number of droplets within a pre-selected range of sizes. Drugs can therefore be tested at the point of delivery, during clinical trials for example, to ensure doses are delivered as intended by the drug developer.</blockquote></p>

<p><strong>Full story:</strong> <a href="http://www.cambridgeconsultants.com/news_pr207.shtml" title="Breakthrough instrument to test inhalable drug delivery devices">Breakthrough instrument to test inhalable drug delivery devices...</a></p>]]>
        
    </content>
</entry>
<entry>
    <title>Chew This Over: Mechanical Mouth Unveiled in France</title>
    <link rel="alternate" type="text/html" href="http://www.medgadget.com/archives/2008/05/chew_this_over_mechanical_mouth_unveiled_in_france.html" />
    <link rel="service.edit" type="application/atom+xml" href="http://www.medgadget.com/cgi-bin/mt-atom.cgi/weblog/blog_id=3/entry_id=5864" title="Chew This Over: Mechanical Mouth Unveiled in France" />
    <id>tag:www.medgadget.com,2008://3.5864</id>
    
    <published>2008-05-07T08:00:04Z</published>
    <updated>2008-05-07T16:18:31Z</updated>
    
    <summary><![CDATA[French researchers have developed an artificial mechanical mouth, which can supposedly munch up food very similarly to how a human mouth does it. The device is intended to be used for testing various foods with regards to quality, and to also understand how flavors are influenced by the physical composition of the food. The munching device mimics the first steps of digestion - chewing, saliva release and food breakdown. About five times the size of a human mouth inside, the steel container is kept at a steady 37&deg;C by an electrical element. Its internal surfaces are coated with a chemically resistant plastic used for medical implants. The ceiling and floor of the cylindrical chamber are attached to variable speed motors. Food is placed on the floor which is able to revolve, while the ceiling coated spiky "teeth" moves up and down like a plunger (see image, right). The compression and rotation simulate the mechanical forces food undergoes in the mouth. The process is made more realistic by the addition of enzyme-containing artificial saliva through a pipe in the base of the chamber. Helium supplied through another inlet flows through the "mouth" to reproduce the effect of breathing and carry volatile compounds away for analysis. More from the New Scientist... Full article in the Journal of Agricultural and Food Chemistry (DOI: 10.1021/jf073145z)...]]></summary>
    <author>
        <name>Michael</name>
        
    </author>
            <category term="in the news..." />
    
    <content type="html" xml:lang="en" xml:base="http://www.medgadget.com/">
        <![CDATA[<p><img class="bside" src="http://www.medgadget.com/archives/img/dn13843-1_500%20%28300%20x%20235%29.jpg" width="300" height="235" />French researchers have developed an artificial mechanical mouth, which can supposedly munch up food very similarly to how a human mouth does it.  The device is intended to be used for testing various foods with regards to quality, and to also understand how flavors are influenced by the physical composition of the food.</p>

<blockquote>The munching device mimics the first steps of digestion - chewing, saliva release and food breakdown. About five times the size of a human mouth inside, the steel container is kept at a steady 37&deg;C by an electrical element. Its internal surfaces are coated with a chemically resistant plastic used for medical implants.

<p>The ceiling and floor of the cylindrical chamber are attached to variable speed motors. Food is placed on the floor which is able to revolve, while the ceiling coated spiky "teeth" moves up and down like a plunger (see image, right).</p>

<p>The compression and rotation simulate the mechanical forces food undergoes in the mouth. The process is made more realistic by the addition of enzyme-containing artificial saliva through a pipe in the base of the chamber.</p>

<p>Helium supplied through another inlet flows through the "mouth" to reproduce the effect of breathing and carry volatile compounds away for analysis.</blockquote></p>

<p><a href="http://technology.newscientist.com/article/dn13843-artificial-mouth-takes-on-a-chewy-problem.html">More</a> from the <em>New Scientist</em>...</p>

<p><a href="http://pubs.acs.org/cgi-bin/sample.cgi/jafcau/asap/html/jf073145z.html">Full article</a> in the <em>Journal of Agricultural and Food Chemistry</em> (DOI: 10.1021/jf073145z)</p>]]>
        
    </content>
</entry>
<entry>
    <title>ei*Nav/Artemis Prostate Ultrasound Machine Receives FDA Clearance</title>
    <link rel="alternate" type="text/html" href="http://www.medgadget.com/archives/2008/05/einavartemis_prostate_ultrasound_machine_receives_fda_clearance.html" />
    <link rel="service.edit" type="application/atom+xml" href="http://www.medgadget.com/cgi-bin/mt-atom.cgi/weblog/blog_id=3/entry_id=5863" title="ei*Nav/Artemis Prostate Ultrasound Machine Receives FDA Clearance" />
    <id>tag:www.medgadget.com,2008://3.5863</id>
    
    <published>2008-05-07T08:00:03Z</published>
    <updated>2008-05-07T16:11:00Z</updated>
    
    <summary><![CDATA[Eigen, a Grass Valley, California company, just received FDA clearance for its 4D ultrasound system specifically designed for urologists to find and track prostate cancer biopsy locations. Using proprietary next-generation 3D/4D imaging, Artemis&trade; provides solutions not available today by enhancing urologists' existing ultrasound machines, the vast majority of which are only 2D. Now, Artemis allows urologists to virtually see inside the prostate in real time during biopsy, guides them with 4D needle navigation during the delicate procedure, maps biopsy locations and generates an image of 3D biopsy coordinates for future reference... Artemis' 3D/4D imaging allows doctors to select and biopsy a location within the boundary of the prostate with pinpoint accuracy. The biopsy location is then recorded by Artemis' patented registration technology, which allows doctors to revisit or avoid the exact same area during repeat procedures. Artemis provides doctors with data they can analyze to determine if the prostate gland has changed and manage treatment accordingly. Product page... Press release: Prostate Cancer Breakthrough Receives FDA Clearance......]]></summary>
    <author>
        <name>Michael</name>
        
    </author>
            <category term="Urology" />
    
    <content type="html" xml:lang="en" xml:base="http://www.medgadget.com/">
        <![CDATA[<p><img class="bside" src="http://www.medgadget.com/archives/img/ei-nav_Artemis.jpg" width="225" height="300" /><strong>Eigen</strong>, a Grass Valley, California company, just received FDA clearance for its 4D ultrasound system specifically designed for urologists to find and track prostate cancer biopsy locations.  </p>

<blockquote>Using proprietary next-generation 3D/4D imaging, Artemis&trade; provides solutions not available today by enhancing urologists' existing ultrasound machines, the vast majority of which are only 2D. Now, Artemis allows urologists to virtually see inside the prostate in real time during biopsy, guides them with 4D needle navigation during the delicate procedure, maps biopsy locations and generates an image of 3D biopsy coordinates for future reference... 

<p>Artemis' 3D/4D imaging allows doctors to select and biopsy a location within the boundary of the prostate with pinpoint accuracy. The biopsy location is then recorded by Artemis' patented registration technology, which allows doctors to revisit or avoid the exact same area during repeat procedures. Artemis provides doctors with data they can analyze to determine if the prostate gland has changed and manage treatment accordingly.</blockquote></p>

<p><a href="http://www.eigen.com/products/artemis.cfm">Product page...</a></p>

<p><strong>Press release:</strong> <a href="http://www.eigen.com/about/events.cfm?EventID=ABE67B78-AE60-869E-FF2E360181AA231A">Prostate Cancer Breakthrough Receives FDA Clearance...</a></p>]]>
        
    </content>
</entry>
<entry>
    <title>Gore Receives EU&apos;s CE Mark for PRECLUDE Vessel Guard</title>
    <link rel="alternate" type="text/html" href="http://www.medgadget.com/archives/2008/05/gore_receives_eus_ce_mark_for_preclude_vessel_guard.html" />
    <link rel="service.edit" type="application/atom+xml" href="http://www.medgadget.com/cgi-bin/mt-atom.cgi/weblog/blog_id=3/entry_id=5865" title="Gore Receives EU's CE Mark for PRECLUDE Vessel Guard" />
    <id>tag:www.medgadget.com,2008://3.5865</id>
    
    <published>2008-05-07T08:00:02Z</published>
    <updated>2008-05-07T16:06:55Z</updated>
    
    <summary><![CDATA[ Gore & Associates has received EU's approval to market its PRECLUDE vessel guard, developed to provide protection for vasculature following anterior spinal surgery for degenerative disc disease, just in case if these surgical patients have to return for a revision procedure. Anterior vertebral re-explorations have inherently increased risks of damage to major abdominal vessels, such as the aorta, the vena cava, and the iliacs. GORE PRECLUDE Vessel Guard enables vasculature management in patients having undergone anterior spinal surgery for degenerative disc disease, including artificial disc replacement (ADR), where scarring around the aorta, vena cava, and iliac vessels can complicate revising, repositioning, or removing a disc prosthesis. An ideal biomaterial for intimate vessel contact and protection, GORE PRECLUDE Vessel Guard is soft and conformable with excellent handling characteristics. The tight microstructured membrane is inserted between the prosthesis and the vessels during the primary surgery. In a revision surgery, the vessels can be identified, dissected from the device and mobilized. GORE PRECLUDE Vessel Guard has a three-layer construction with two outer layers consisting of a tight expanded polytetrafluoroethylene (ePTFE) microstructure preventing penetration by fibroblasts, thus minimizing vascular tissue attachment to the device, allowing safer anterior revision. GORE PRECLUDE Vessel Guard is also easy to use--an elastomeric inner layer minimizes impingement and provides the stiffness needed for accurate placement. The material may be trimmed and tailored without fraying. The U.S. Food & Drug Administration (FDA) cleared GORE PRECLUDE Vessel Guard indicated for vessel protection in August 2006. Press release: Gore Receives CE Mark for GORE PRECLUDE&reg; Vessel Guard Video (Windows Media): 14-Month Revision Surgery with a GORE ePTFE Membrane Product page......]]></summary>
    <author>
        <name>Michael</name>
        
    </author>
            <category term="Neurological Surgery" />
            <category term="Orthopedic Surgery" />
            <category term="Vascular Surgery" />
    
    <content type="html" xml:lang="en" xml:base="http://www.medgadget.com/">
        <![CDATA[<p><img class="bcntr" src="http://www.medgadget.com/archives/img/vascularguard.jpg" width="468" height="327" /><br />
<strong>Gore & Associates</strong> has received EU's approval to market its PRECLUDE vessel guard, developed to provide protection for vasculature following anterior spinal surgery for degenerative disc disease, just in case if these surgical patients have to return for a revision procedure. Anterior vertebral re-explorations have inherently increased risks of damage to major abdominal vessels, such as the aorta, the vena cava, and the iliacs.</p>

<blockquote>GORE PRECLUDE Vessel Guard enables vasculature management in patients having undergone anterior spinal surgery for degenerative disc disease, including artificial disc replacement (ADR), where scarring around the aorta, vena cava, and iliac vessels can complicate revising, repositioning, or removing a disc prosthesis.
An ideal biomaterial for intimate vessel contact and protection, GORE PRECLUDE Vessel Guard is soft and conformable with excellent handling characteristics. The tight microstructured membrane is inserted between the prosthesis and the vessels during the primary surgery. In a revision surgery, the vessels can be identified, dissected from the device and mobilized.
 
GORE PRECLUDE Vessel Guard has a three-layer construction with two outer layers consisting of a tight expanded polytetrafluoroethylene (ePTFE) microstructure preventing penetration by fibroblasts, thus minimizing vascular tissue attachment to the device, allowing safer anterior revision. GORE PRECLUDE Vessel Guard is also easy to use--an elastomeric inner layer minimizes impingement and provides the stiffness needed for accurate placement. The material may be trimmed and tailored without fraying.

<p>The U.S. Food & Drug Administration (FDA) cleared GORE PRECLUDE Vessel Guard indicated for vessel protection in August 2006.</blockquote></p>

<p><strong>Press release:</strong> <a href="http://www.gore.com/en_xx/news/CEmark-PRECLUDE.html">Gore Receives CE Mark for GORE PRECLUDE&reg; Vessel Guard</a></p>

<p>Video (Windows Media): <a href="mms://wm.vitalstreamcdn.com/goremedical_vitalstream_com/MPD-Library/VESSELGUARD_Garber.wmv">14-Month Revision Surgery with a GORE ePTFE Membrane</a></p>

<p><a href="http://www.goremedical.com/vesselguard">Product page</a>...</p>]]>
        
    </content>
</entry>
<entry>
    <title>The SolarAid Revisited</title>
    <link rel="alternate" type="text/html" href="http://www.medgadget.com/archives/2008/05/the_solaraid_revisited.html" />
    <link rel="service.edit" type="application/atom+xml" href="http://www.medgadget.com/cgi-bin/mt-atom.cgi/weblog/blog_id=3/entry_id=5867" title="The SolarAid Revisited" />
    <id>tag:www.medgadget.com,2008://3.5867</id>
    
    <published>2008-05-07T08:00:01Z</published>
    <updated>2008-05-07T15:54:47Z</updated>
    
    <summary><![CDATA[Two years ago we reported on the SolarAid, a low cost solar-powered hearing aid intended for the hearing-impaired in developing countries. A recent article in Newsweek looks at the success of the device and gives a little insight into the mind behind it, Howard Weinstein: Weinstein knew what he had to do: change the business model. Drawing on his years in the corporate bunker, he started working the phones, chatting up financiers, consulting with electronics wizards and haggling with manufacturers. He landed a small grant from the U.S. government-run African Development Foundation and, with help from some dedicated electronics geeks and industry execs willing to forgo their usual profits, came up with something new: a cheap hearing aid powered by rechargeable solar batteries. It looked ordinary enough&mdash;just a cashew-shaped piece of plastic to tuck behind the ear&mdash;but it cost less than $100, a fifth the price of the cheapest retail model. Rechargeable batteries, $1 apiece, last two to three years. None of this was much use without a reliable power source, so he also built a pocket-size recharger that can either plug into a wall outlet or use its own built-in solar panel. Weinstein has tapped into another source of underused energy: deaf people. &quot;Because mastering sign language takes acute hand-eye coordination, deaf people are well suited to the fine soldering and microelectronics that go into making hearing aids,&quot; he says. Today the once empty room in the African semi desert has become the hub of a thriving nonprofit business. Some 20,000 people in 30 countries are using SolarAid brand hearing aids, chargers and batteries. With funding from the Ashoka Foundation and the Oregon-based Lemelson Foundation, Weinstein is working with engineers from the University of S&atilde;o Paulo on a second-generation, digital hearing aid. He sees Brazil as a beachhead for all of Latin America; he plans to set up another nonprofit company in Jordan to reach the entire Middle East. Then he'll take on China and India. All told, he hopes to employ 1,000 deaf people over the next three to five years. Read the whole article here......]]></summary>
    <author>
        <name>jhbarad</name>
        
    </author>
            <category term="in the news..." />
    
    <content type="html" xml:lang="en" xml:base="http://www.medgadget.com/">
        <![CDATA[<p><img alt="" class="bside" src="http://www.medgadget.com/archives/img/solar-aid.jpg" width="300" height="182" />Two years ago we reported on the <a href="http://www.medgadget.com/archives/2006/01/the_solaraid_1.html">SolarAid</a>, a low cost solar-powered hearing aid intended for the hearing-impaired in developing countries.  A recent article in <em>Newsweek</em> looks at the success of the device and gives a little insight into the mind behind it, Howard Weinstein:</p>

<blockquote>Weinstein knew what he had to do: change the business model. Drawing on his years in the corporate bunker, he started working the phones, chatting up financiers, consulting with electronics wizards and haggling with manufacturers. He landed a small grant from the U.S. government-run African Development Foundation and, with help from some dedicated electronics geeks and industry execs willing to forgo their usual profits, came up with something new: a cheap hearing aid powered by rechargeable solar batteries. It looked ordinary enough&mdash;just a cashew-shaped piece of plastic to tuck behind the ear&mdash;but it cost less than $100, a fifth the price of the cheapest retail model. Rechargeable batteries, $1 apiece, last two to three years. None of this was much use without a reliable power source, so he also built a pocket-size recharger that can either plug into a wall outlet or use its own built-in solar panel.

<p>Weinstein has tapped into another source of underused energy: deaf people. &quot;Because mastering sign language takes acute hand-eye coordination, deaf people are well suited to the fine soldering and microelectronics that go into making hearing aids,&quot; he says. Today the once empty room in the African semi desert has become the hub of a thriving nonprofit business. Some 20,000 people in 30 countries are using SolarAid brand hearing aids, chargers and batteries. With funding from the Ashoka Foundation and the Oregon-based Lemelson Foundation, Weinstein is working with engineers from the University of S&atilde;o Paulo on a second-generation, digital hearing aid. He sees Brazil as a beachhead for all of Latin America; he plans to set up another nonprofit company in Jordan to reach the entire Middle East. Then he'll take on China and India. All told, he hopes to employ 1,000 deaf people over the next three to five years.</blockquote></p>

<p>Read the whole article <a href="http://www.newsweek.com/id/135381">here</a>...</p>]]>
        
    </content>
</entry>
<entry>
    <title>Sentinelle Vanguard Breast MR Auxiliary Table</title>
    <link rel="alternate" type="text/html" href="http://www.medgadget.com/archives/2008/05/sentinelle_vanguard_breast_mr_auxiliary_table.html" />
    <link rel="service.edit" type="application/atom+xml" href="http://www.medgadget.com/cgi-bin/mt-atom.cgi/weblog/blog_id=3/entry_id=5862" title="Sentinelle Vanguard Breast MR Auxiliary Table" />
    <id>tag:www.medgadget.com,2008://3.5862</id>
    
    <published>2008-05-06T08:02:43Z</published>
    <updated>2008-05-06T09:00:13Z</updated>
    
    <summary><![CDATA[ Sentinelle Medical Inc., a Toronto, Ontario firm, is reporting that its president Mr. Cameron Piron was just recognized as Best Young Innovator by the Ontario Ministry of Research and Innovation. Putting aside the whole twisted idea of "Ministry of Research and Innovation", we ventured to check out the product of Sentinelle Medical. It turns out that the product, called Sentinelle Vanguard Breast MR Auxiliary Table&reg;, is a pretty clever device. Designed to work in tandem with GE Healtcare's Signa&reg; HDx 1.5T MRI system, the table features an eight channel coil array that enhances imaging of the breast, while the configuration of the table makes percutaneous biopsies (and other interventions) more tolerable for the clinician and the patient, thanks to an open design that offers easy accessibility to all quadrants of the breast. More about the system: Variable Coil Geometry&reg; of the 8 channel array allows the position of the coils to be customized for every patient. Vanguard&reg; coils can be moved medially and laterally, as well as posteriorally towards the axilla and chest wall providing improvements to image quality unavailable on traditional tabletop coils The unique coil geometry improves overall signal to noise ratio which can result in higher resolution images. Higher resolution images provide more detailed information and may promote earlier detection of lesions. This can, in turn, result in better management of disease and treatment... Complete and open medial and lateral access provided by the Vanguard&reg; design allows interventions to all quadrants of the breast. The system employs adjustable interventional grids which can be moved medially and laterally as well as towards the axilla and chest wall, providing access to lesions in the inner upper and outer upper quadrants of the breast. Use of a removable sternum support and support plate improves access to lesions near the chest wall in medial approaches. The Vanguard&reg; works in combination with several biopsy devices and localization needles... A Significant amount of effort has been put into the design and padding of the patient support. Increased patient clearance in the bore means that more patients can be comfortably positioned with arms by their side. This improves comfort for the patient and reduces motion during the exam. The &lsquo;wings&rsquo; of the system not only provide support for this positioning but also protect the patient from the magnet. The padding used is made of visco-elastic foam providing improved comfort especially in common pressure...]]></summary>
    <author>
        <name>Michael</name>
        
    </author>
            <category term="Ob/Gyn" />
            <category term="Radiology" />
            <category term="Surgery" />
    
    <content type="html" xml:lang="en" xml:base="http://www.medgadget.com/">
        <![CDATA[<p><img alt="" class="bcntr" src="http://www.medgadget.com/archives/img/4534van1.jpg" width="468" height="344" /><br />
<strong>Sentinelle Medical</strong> Inc., a Toronto, Ontario firm, is reporting that its president Mr. Cameron Piron was just recognized as Best Young Innovator by the Ontario Ministry of Research and Innovation. Putting aside the whole twisted idea of "Ministry of Research and Innovation", we ventured to check out the product of <strong>Sentinelle Medical</strong>. It turns out that the product, called Sentinelle Vanguard Breast MR Auxiliary Table&reg;, is a pretty clever device. Designed to work in tandem with GE Healtcare's Signa&reg; HDx 1.5T MRI system, the table features an eight channel coil array that enhances imaging of the breast, while the configuration of the table makes percutaneous biopsies (and other interventions) more tolerable for the clinician and the patient, thanks to an open design that offers easy accessibility to all quadrants of the breast.</p>

<p><img alt="" class="bcntr" src="http://www.medgadget.com/archives/img/4534van2.jpg" width="468" height="250" /><br />
More about the system:</p>

<blockquote>Variable Coil Geometry&reg; of the 8 channel array allows the position of the coils to be customized for every patient. Vanguard&reg; coils can be moved medially and laterally, as well as posteriorally towards the axilla and chest wall providing improvements to image quality unavailable on traditional tabletop coils

<p>The unique coil geometry improves overall signal to noise ratio which can result in higher resolution images. Higher resolution images provide more detailed information and may promote earlier detection of lesions. This can, in turn, result in better management of disease and treatment...</p>

<p>Complete and open medial and lateral access provided by the Vanguard&reg; design allows interventions to all quadrants of the breast. The system employs adjustable interventional grids which can be moved medially and laterally as well as towards the axilla and chest wall, providing access to lesions in the inner upper and outer upper quadrants of the breast. Use of a removable sternum support and support plate improves access to lesions near the chest wall in medial approaches.</p>

<p>The Vanguard&reg; works in combination with several biopsy devices and localization needles...</p>

<p>A Significant amount of effort has been put into the design and padding of the patient support.  Increased patient clearance in the bore means that more patients can be comfortably positioned with arms by their side. This improves comfort for the patient and reduces motion during the exam. The &lsquo;wings&rsquo; of the system not only provide support for this positioning but also protect the patient from the magnet.</p>

<p>The padding used is made of visco-elastic foam providing improved comfort especially in common pressure areas such as the diaphragm and sternum. All padding is adjustable, allowing customized cushioning for every patient. The foam is covered in surgical grade material allowing for easy clean up.</p>

<p>The Sentinelle Vanguard Breast MR Auxiliary Table&reg; is a comprehensive system. All features, including storage drawers, tray tables, biopsy grids, padding, safety rails, movable sternum supports, and integrated lighting are designed to work together for improved workflow. The Vanguard&reg; is the only dedicated, detachable table design available for Breast MR.</p>

<p>The Vanguard&rsquo;s&reg; unique detachable table design allows patient preparation prior to and after both imaging and intervention to be performed outside the MR suite. Used in conjunction with the standard Signa&trade; detachable table, this results in significant savings in per-patient magnet use time. Experience with Vanguard&reg; has shown an average efficiency increase of 10-25 minutes per patient.</blockquote></p>

<p><strong>Product page:</strong> <a href="http://www.sentinellemedical.com/VanguardBreastMRAuxiliaryTable.html" title="Sentinelle Vanguard Breast MR Auxiliary Table">Sentinelle Vanguard Breast MR Auxiliary Table...</a></p>

<p><strong>Press release:</strong> <a href="http://www.sentinellemedical.com/files/2008%2004%2029%20-%20Ministry%20News%20Release%20for%20PIA.pdf" title="">Cameron Piron, president of Sentinelle Medical Inc., recognized as Best Young Innovator by the Ontario Ministry of Research and Innovation (.pdf)...</a> </p>

<p>(hat tip: <a href="http://inventorspot.com/articles/canadian_invents_mri_table_for_better_breast_cancer_detection_13351" title="Boomer Babe">Boomer Babe</a>)</p>]]>
        
    </content>
</entry>
<entry>
    <title>Study: Kids Love Zingo No Needles Local Anesthesia</title>
    <link rel="alternate" type="text/html" href="http://www.medgadget.com/archives/2008/05/study_kids_love_zingo_needless_local_anesthesia.html" />
    <link rel="service.edit" type="application/atom+xml" href="http://www.medgadget.com/cgi-bin/mt-atom.cgi/weblog/blog_id=3/entry_id=5861" title="Study: Kids Love Zingo No Needles Local Anesthesia" />
    <id>tag:www.medgadget.com,2008://3.5861</id>
    
    <published>2008-05-06T08:00:08Z</published>
    <updated>2008-05-06T08:56:30Z</updated>
    
    <summary><![CDATA[ William T. Zempsky, MD, from the Connecticut Children's Medical Center, and colleagues from five other hospitals just published a randomized, double-blind study in the latest issue of Pediatrics, that has shown that a "needle-free powder lidocaine delivery system was well tolerated and produced significant analgesia within 1 to 3 minutes," in pediatric patients scheduled to undergo venipuncture or cannulation. The system used in the study was Zingo&trade; lidocaine powder intradermal injector from Anesiva, Inc., a South San Francisco, CA company. The system, that uses compressed gas to accelerate the lidocaine particles under the skin, was approved by the FDA in August 2007, " to reduce the pain associated with peripheral IV insertions or blood draws in children three to 18 years of age." To learn more about Zingo&trade;, head on to this product page @ Anesiva... Abstract: Needle-Free Powder Lidocaine Delivery System Provides Rapid Effective Analgesia for Venipuncture or Cannulation Pain in Children: Randomized, Double-Blind Comparison of Venipuncture and Venous Cannulation Pain After Fast-Onset Needle-Free Powder Lidocaine or Placebo Treatment Trial PEDIATRICS Vol. 121 No. 5 May 2008, pp. 979-987 Zingo&trade; prescribing info (.pdf)......]]></summary>
    <author>
        <name>Michael</name>
        
    </author>
            <category term="Anesthesiology" />
            <category term="Emergency Medicine" />
            <category term="Pediatrics" />
    
    <content type="html" xml:lang="en" xml:base="http://www.medgadget.com/">
        <![CDATA[<p><img alt="" class="cntr" src="http://www.medgadget.com/archives/img/43435zingo.jpg" width="429" height="108" /><br />
William T. Zempsky, MD, from the Connecticut Children's Medical Center, and colleagues from five other hospitals just published a randomized, double-blind study in the latest issue of <em>Pediatrics</em>, that has shown that a "needle-free powder lidocaine delivery system was well tolerated and produced significant analgesia within 1 to 3 minutes," in pediatric patients scheduled to undergo venipuncture or cannulation. <img alt="" class="bside" src="http://www.medgadget.com/archives/img/43435zing2.jpg" width="239" height="239" />The system used in the study was Zingo&trade; lidocaine powder intradermal injector from <strong>Anesiva</strong>, Inc., a South San Francisco, CA company. The system, that uses compressed gas to accelerate the lidocaine particles under the skin, was approved by the FDA in August 2007, " to reduce the pain associated with peripheral IV insertions or blood draws in children three to 18 years of age."</p>

<p>To learn more about Zingo&trade;, head on to this <a href="http://www.anesiva.com/wt/page/prod_zingo">product page</a> @ Anesiva...</p>

<p><strong>Abstract:</strong> <a href="http://pediatrics.aappublications.org/cgi/content/abstract/121/5/979" title="Needle-Free Powder Lidocaine Delivery System Provides Rapid Effective Analgesia for Venipuncture or Cannulation Pain in Children: Randomized, Double-Blind Comparison of Venipuncture and Venous Cannulation Pain After Fast-Onset Needle-Free Powder Lidocaine or Placebo Treatment Trial">Needle-Free Powder Lidocaine Delivery System Provides Rapid Effective Analgesia for Venipuncture or Cannulation Pain in Children: Randomized, Double-Blind Comparison of Venipuncture and Venous Cannulation Pain After Fast-Onset Needle-Free Powder Lidocaine or Placebo Treatment Trial</a> <em>PEDIATRICS</em> Vol. 121 No. 5 May <strong>2008</strong>, pp. 979-987</p>

<p>Zingo&trade; <a href="http://www.anesiva.com/img/ZingoPackage.pdf">prescribing info (.pdf)</a>...</p>]]>
        
    </content>
</entry>
<entry>
    <title>McSleepy: Automated Anesthesia System</title>
    <link rel="alternate" type="text/html" href="http://www.medgadget.com/archives/2008/05/mcsleepy_automated_anesthesia_system.html" />
    <link rel="service.edit" type="application/atom+xml" href="http://www.medgadget.com/cgi-bin/mt-atom.cgi/weblog/blog_id=3/entry_id=5860" title="McSleepy: Automated Anesthesia System" />
    <id>tag:www.medgadget.com,2008://3.5860</id>
    
    <published>2008-05-06T08:00:05Z</published>
    <updated>2008-05-06T08:55:42Z</updated>
    
    <summary>Canadian Researchers at McGill University in Montreal, Quebec and the McGill University Health Centre (MUHC) have developed an automated anesthetic system and believe they were the first in the world to perform a surgery with such a machine. The new system, named &apos;McSleepy&apos; - in honor of the nicknames given to the doctors on the TV show &apos;Grey&apos;s Anatomy&apos; - will administer drugs and monitor vital signs for patients undergoing surgery. So far, the system has been used during seven operations, and according to Dr. Thomas Hemmerling, principal developer for the system at McGill University, the preliminary results show that &quot;...it is actually better in terms of stability of anesthesia than us at this point&quot;. Think of &quot;McSleepy&quot; as a sort of humanoid anesthesiologist that thinks like an anesthesiologist, analyses biological information and constantly adapts its own behavior, even recognizing monitoring malfunction. The anesthetic technique was used on a patient who underwent a partial nephrectomy, a procedure that removes a kidney tumor while leaving the non-cancerous part of the kidney intact, over a period of three hours and 30 minutes. To manipulate the various components of general anesthesia, the automated system measures three separate parameters displayed on a new Integrated monitor of anesthesia (IMATM): depth of hypnosis via EEG analysis, pain via a new pain score, called AnalgoscoreTM, and muscle relaxation via phonomyographyTM, all developed by ITAG. The system then administers the appropriate drugs using conventional infusion pumps, controlled by a laptop computer on which &quot;McSleepy&quot; is installed. Using these three separate parameters and complex algorithms, the automated system calculates faster and more precisely than a human can the appropriate drug doses for any given moment of anesthesia. &quot;McSleepy&quot; assists the anesthesiologist in the same way an automatic transmission assists people when driving. As such, anesthesiologists can focus more on other aspects of direct patient care. An additional feature is that the system can communicate with personal digital assistants (PDAs), making distant monitoring and anesthetic control possible. In addition, this technology can be easily incorporated into modern medical teaching programs such as simulation centers and web-based learning platforms. More from AOL Health: Canadian researchers develop automated anesthesia system dubbed McSleepy Press Release: McSleepy hopes to revolutionize anesthesia practice...</summary>
    <author>
        <name>Rohit Joshi</name>
        
    </author>
            <category term="Anesthesiology" />
    
    <content type="html" xml:lang="en" xml:base="http://www.medgadget.com/">
        <![CDATA[<p><img alt="mcsleepy.jpg" class="bside" src="http://www.medgadget.com/archives/img/mcsleepy.jpg" width="300" height="202" />Canadian Researchers at McGill University in Montreal, Quebec and the McGill University Health Centre (MUHC) have developed an automated anesthetic system and believe they were the first in the world to perform a surgery with such a machine.  The new system, named 'McSleepy' - in honor of the nicknames given to the doctors on the TV show 'Grey's Anatomy' - will administer drugs and monitor vital signs for patients undergoing surgery.  So far, the system has been used during seven operations, and according to Dr. Thomas Hemmerling, principal developer for the system at McGill University, the preliminary results show that "...it is actually better in terms of stability of anesthesia than us at this point".<br />
<blockquote>Think of "McSleepy" as a sort of humanoid anesthesiologist that thinks like an anesthesiologist, analyses biological information and constantly adapts its own behavior, even recognizing monitoring malfunction.</p>

<p>The anesthetic technique was used on a patient who underwent a partial nephrectomy, a procedure that removes a kidney tumor while leaving the non-cancerous part of the kidney intact, over a period of three hours and 30 minutes. To manipulate the various components of general anesthesia, the automated system measures three separate parameters displayed on a new Integrated monitor of anesthesia (IMATM): depth of hypnosis via EEG analysis, pain via a new pain score, called AnalgoscoreTM, and muscle relaxation via phonomyographyTM, all developed by ITAG. The system then administers the appropriate drugs using conventional infusion pumps, controlled by a laptop computer on which "McSleepy" is installed.</p>

<p>Using these three separate parameters and complex algorithms, the automated system calculates faster and more precisely than a human can the appropriate drug doses for any given moment of anesthesia. "McSleepy" assists the anesthesiologist in the same way an automatic transmission assists people when driving. As such, anesthesiologists can focus more on other aspects of direct patient care. An additional feature is that the system can communicate with personal digital assistants (PDAs), making distant monitoring and anesthetic control possible. In addition, this technology can be easily incorporated into modern medical teaching programs such as simulation centers and web-based learning platforms.</blockquote></p>

<p>More from <em>AOL Health</em>: <a href="http://aol.mediresource.com/channel_health_news_details.asp?news_id=15225&news_channel_id=41&channel_id=41&article_rating=4)">Canadian researchers develop automated anesthesia system dubbed McSleepy</a></p>

<p>Press Release: <a href="http://www.mcgill.ca/newsroom/news/item/?item_id=100263"http://www.mcgill.ca/newsroom/news/item/?item_id=100263_">McSleepy hopes to revolutionize anesthesia practice</a></p>]]>
        
    </content>
</entry>
<entry>
    <title>Study Shows Incubators Change Babies&apos; Heartbeat</title>
    <link rel="alternate" type="text/html" href="http://www.medgadget.com/archives/2008/05/study_shows_incubators_change_babies_heartbeats.html" />
    <link rel="service.edit" type="application/atom+xml" href="http://www.medgadget.com/cgi-bin/mt-atom.cgi/weblog/blog_id=3/entry_id=5859" title="Study Shows Incubators Change Babies' Heartbeat" />
    <id>tag:www.medgadget.com,2008://3.5859</id>
    
    <published>2008-05-06T08:00:03Z</published>
    <updated>2008-05-06T08:49:54Z</updated>
    
    <summary>Carlo Bellieni, et. al. from the University of Siena, Italy published a study in the latest Archives of Disease in Childhood that apparently shows changes in heart rate variability (HRV) in a small group of newborns in a neonatal ICU. The authors believe that electromagnetic fields in incubators, as documented in changes in HRV throughout three 5-minute periods (with incubator motor on, off, and on again), have some kind of effect on the neonatal autonomous nervous system. To learn more about the study, read this editorial in Nature... Abstract: Electromagnetic fields produced by incubators influence heart rate variability in newborns Arch. Dis. Child. Fetal Neonatal Ed..2008; 0: adc.2007.132738v2 Image credit: keaggy.com @ Flickr: My Blue Girl......</summary>
    <author>
        <name>Michael</name>
        
    </author>
            <category term="in the news..." />
    
    <content type="html" xml:lang="en" xml:base="http://www.medgadget.com/">
        <![CDATA[<p><img alt="" class="bside" src="http://www.medgadget.com/archives/img/567676nicu.jpg" width="300" height="225" />Carlo Bellieni, <em>et. al.</em> from the University of Siena, Italy published a study in the latest <em>Archives of Disease in Childhood</em> that apparently shows changes in heart rate variability (HRV) in a small group of newborns in a neonatal ICU. The authors believe that electromagnetic fields in incubators, as documented in changes in HRV throughout three 5-minute periods (with incubator motor on, off, and on again), have some kind of effect on the neonatal autonomous nervous system. </p>

<p>To learn more about the study, read <a href="http://www.nature.com/news/2008/080430/full/news.2008.790.html">this editorial</a> in <em>Nature</em>...</p>

<p><strong>Abstract:</strong> <a href="http://fn.bmj.com/cgi/content/abstract/adc.2007.132738v2" title="Electromagnetic fields produced by incubators influence heart rate variability in newborns">Electromagnetic fields produced by incubators influence heart rate variability in newborns</a> <em>Arch. Dis. Child. Fetal Neonatal Ed.</em>.<strong>2008</strong>; 0: adc.2007.132738v2</p>

<p><strong>Image credit</strong>: keaggy.com @ Flickr: <a href="http://flickr.com/photos/bk/10021607/" title="My Blue Girl">My Blue Girl...</a></p>]]>
        
    </content>
</entry>
<entry>
    <title>VascuSeal Goes on Sale in Europe</title>
    <link rel="alternate" type="text/html" href="http://www.medgadget.com/archives/2008/05/vascuseal.html" />
    <link rel="service.edit" type="application/atom+xml" href="http://www.medgadget.com/cgi-bin/mt-atom.cgi/weblog/blog_id=3/entry_id=5850" title="VascuSeal Goes on Sale in Europe" />
    <id>tag:www.medgadget.com,2008://3.5850</id>
    
    <published>2008-05-06T08:00:02Z</published>
    <updated>2008-05-06T08:47:37Z</updated>
    
    <summary>Covidien, a US company with executive headquarters in Bermuda, is introducing its CE Mark approved vascular sealant system to the European market. Unlike a hemostatic agent, a vascular sealant can seal blood leaks and does not depend on either the time for the blood to clot or the strength of the blood clot to perform successfully. The VascuSeal(TM) Sealant System offers surgeons a valuable tool to reduce bleeding from the suture line in vascular bypass procedures, and reduces post-operative complications associated with suture line bleeding. The VascuSeal(TM) sealant technology is a patented synthetic, absorbable hydrogel delivered by a dual syringe applicator. The device can be stored at room temperature and prepared in less than two minutes. VascuSeal(TM) sealant polymerizes within seconds when sprayed on the suture line and is blue in color which provides the vascular surgeon visualization of coverage and thickness of the material upon application. Postoperatively, VascuSeal(TM) sealant continues to seal the suture line as healing progresses under the gel. After several days, the hydrogel breaks down into water-soluble molecules that are absorbed and cleared through the kidneys. Press release: Covidien Introduces the VascuSeal(TM) Vascular Sealant System to the European Marketplace...</summary>
    <author>
        <name>Michael</name>
        
    </author>
            <category term="Vascular Surgery" />
    
    <content type="html" xml:lang="en" xml:base="http://www.medgadget.com/">
        <![CDATA[<p><img class="bside" src="http://www.medgadget.com/archives/img/vascuseal.jpg" width="300" height="194" /><strong>Covidien</strong>, a US company with executive headquarters in Bermuda, is introducing its CE Mark approved vascular sealant system to the European market. </p>

<blockquote>Unlike a hemostatic agent, a vascular sealant can seal blood leaks and does not depend on either the time for the blood to clot or the strength of the blood clot to perform successfully. The VascuSeal(TM) Sealant System offers surgeons a valuable tool to reduce bleeding from the suture line in vascular bypass procedures, and reduces post-operative complications associated with suture line bleeding.

<p>The VascuSeal(TM) sealant technology is a patented synthetic, absorbable hydrogel delivered by a dual syringe applicator. The device can be stored at room temperature and prepared in less than two minutes. VascuSeal(TM) sealant polymerizes within seconds when sprayed on the suture line and is blue in color which provides the vascular surgeon visualization of coverage and thickness of the material upon application. Postoperatively, VascuSeal(TM) sealant continues to seal the suture line as healing progresses under the gel. After several days, the hydrogel breaks down into water-soluble molecules that are absorbed and cleared through the kidneys. </blockquote></p>

<p>Press release: <a href="http://investor.covidien.com/preview/phoenix.zhtml?c=207592&p=irol-newsArticle&id=1138240">Covidien Introduces the VascuSeal(TM) Vascular Sealant System to the European Marketplace</a></p>]]>
        
    </content>
</entry>

</feed> 