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<title>Medgadget</title>
<link>http://www.medgadget.com/</link>
<description>Internet journal of emerging medical technologies.</description>
<copyright>Copyright 2008</copyright>
<lastBuildDate>Tue, 19 Aug 2008 12:24:23 -0800</lastBuildDate>
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<item>
<title>Digital Lightbox Brings Minority Report to The OR (No Precognition Capabilities)</title>
<description><![CDATA[<p><img class="bcntr" src="http://www.medgadget.com/archives/img/Digital-LightBox.jpg" width="468" height="356" /><br />
<strong>BrainLAB</strong> AG, out of Feldkirchen, Germany has recently installed its first Digital Lightbox radiology system in a Munich hospital.  Designed to be installed in radiology departments, clinical floors, and  operating rooms, the system behaves like a giant iPhone, simultaneously displaying volumetric images from various imaging modalities along with patient information.</p>

<blockquote>Digital Lightbox replaces the conventional light box used to observe analog x-ray images. Connected to the hospital PACS, the new digital platform can be installed both in meeting rooms and in operating rooms, where clinicians can then access, manipulate, and utilize data for surgery planning. By displaying the human body in 3D, Digital Lightbox helps clinicians to more clearly demonstrate to patients what effects a disease can have and which procedures may be necessary.

<p>Digital Lightbox enables clinicians to select the most valuable images from large amounts of existing medical data. Ergonomic touchscreen technology with zoom functionality makes working with data easy and effective.</p>

<p>Clinicians can intuitively navigate within pictures and between settings. Image scrolling can be performed with one finger; zooming in and out of images with two. Images from different sources can also be fused easily. A measure functionality enables clinicians to set size and other dimensions.</p>

<p>By integrating the communication platform iPlan&reg; Net from BrainLAB, clinicians can perform treatment planning with Digital Lightbox or any PC connected to the hospital network. This eliminates bottlenecks, as busy planning stations are rendered obsolete. iPlan Net helps to simplify the clinical workflow and save costs, as well as strengthen and simplify interdisciplinary collaboration between neurosurgery, nuclear medicine and radiology departments.</p>

<p>Digital Lightbox can be installed in any hospital environment and is compatible with all established image formats, such as DICOM, jpg, bmp, tif, png, avi, wmv. Planning data can be transferred directly from Digital Lightbox to surgical navigation systems designed for precise and minimally invasive procedures.</blockquote></p>

<p>Video demonstrating the Digital Lightbox:</p>

<center><object width="425" height="350"> <param name="movie" value="http://www.youtube.com/v/0OPDaAe9AE8"> </param> <embed src="http://www.youtube.com/v/0OPDaAe9AE8" type="application/x-shockwave-flash" width="425" height="350"> </embed> </object></center>

<p><strong>Press release:</strong> <a href="http://www.brainlab.com/scripts/website_english.asp?articleID=2544&articleTypeID=273&pageTypeID=5&article_short_headline=July%2031,%202008%3Cbr%3EWorld%20Premiere%20at%20University%20Hospital%20in%20Munich:%20Digital%20Lightbox%3Cbr%3E" title="World Premiere at University Hospital in Munich: Digital Lightbox">World Premiere at University Hospital in Munich: Digital Lightbox...</a></p>

<p><strong>Product page</strong>: <a href="http://www.brainlab.com/scripts/website_english.asp?menuDeactivate=1&articleID=2514&articleTypeID=276&pageTypeID=6&article_short_headline=Discover%20Digital%20Lightbox%C2%A9">Digital Lightbox</a></p>]]></description>
<link>http://www.medgadget.com/archives/2008/08/digital_lightbox_brings_minority_report_to_the_or_no_precognition_capabilities.html</link>
<guid>http://www.medgadget.com/archives/2008/08/digital_lightbox_brings_minority_report_to_the_or_no_precognition_capabilities.html</guid>
<category>Radiology</category>
<pubDate>Tue, 19 Aug 2008 12:24:23 -0800</pubDate>
</item>
<item>
<title>The ShangRing Circumcision Device</title>
<description><![CDATA[<p><img alt="" class="bcntr" src="http://www.medgadget.com/archives/img/67566shaq.jpg" width="468" height="241" /><br />
A device invented by Jianzhong Shang, a Chinese inventor from Wuhu City, is poised to become not only a new generation mohel-assist device, but a major medgadget in the world wide fight to prevent HIV.</p>

<p>Clinicians from NewYork-Presbyterian Hospital/Weill Cornell Medical Center are studying the two-ring device to see its efficacy and applicability for the African population and beyond.</p>

<p>From the NewYork-Presbyterian Hospital/Weill Cornell Medical Center press release:</p>

<blockquote>With the recent endorsement by the World Health Organization (WHO) and scientists worldwide of adult male circumcision as an important strategy for HIV prevention, there is increased urgency to develop safe and cost-effective circumcision services. This is especially the case in Africa where HIV/AIDS continues to spread at an epidemic rate.

<p>Studying this method are Dr. Marc Goldstein and physician-scientists at NewYork-Presbyterian Hospital/Weill Cornell Medical Center, who are evaluating an innovative circumcision device developed in China and will initiate a study of the device in Africa in the coming months.</p>

<p>The device, named the ShangRing after its inventor, Mr. Jian-Zhong Shang, consists of two concentric plastic rings that sandwich the foreskin, allowing it to be cut away without suturing and with minimal bleeding. Performed in a clinic under local anesthesia, the procedure takes less than five minutes, compared with approximately 20 to 30 minutes for a traditional "free hands" circumcision that requires suturing. The patient returns in one week for device removal.</p>

<p>"Circumcision with this technique promises to be faster, safer and more acceptable to patients than conventional surgical circumcision methods," says Dr. Goldstein, the study's principal investigator. He is urologist and specialist in reproductive medicine at NewYork-Presbyterian Hospital/Weill Cornell Medical Center, the Matthew P. Hardy Distinguished Professor of Reproductive Medicine and Urology at Weill Cornell Medical College, and senior scientist at The Population Council, Center for Biomedical Research, located on the campus of The Rockefeller University.</p>

<p><br />
The ShangRing has been used to circumcise several thousand Chinese men since 2005. Preliminary reports of 1,200 patients indicate good results with minimal complications. The ShangRing, with 15 patents pending in 85 countries, is currently available only in China. FDA evaluation is under way.</blockquote></p>

<p>We tried to obtain images of this device, <s>but unfortunately we failed. (Anyone out there can get them for us?)</s>To further understand how the device works, attached is the United States Patent Application recently filed by Mr. Shang with USPTO.</p>

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<p><strong>Press release:</strong> <a href="http://news.med.cornell.edu/wcmc/wcmc_2008/07_31b_08.shtml" title="New Male Circumcision Device for HIV Prevention Studied by NewYork-Presbyterian/Weill Cornell">New Male Circumcision Device for HIV Prevention Studied by NewYork-Presbyterian/Weill Cornell...</a></p>

<p>United States Patent Application # 20080154283: <br />
<a href="http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&amp;Sect2=HITOFF&amp;p=1&amp;u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&amp;r=1&amp;f=G&amp;l=50&amp;co1=AND&amp;d=PG01&amp;s1=20080154283&amp;OS=20080154283&amp;RS=20080154283" title="United States Patent Application 20080154283">Apparatus for circumcising a penis</a></p>

<p><strong>UPDATE:</strong> Hurrah!  Weill Cornell Medical College has kindly provided us with the picture of ShangRing device.</p>]]></description>
<link>http://www.medgadget.com/archives/2008/08/the_shangring_circumcision_device.html</link>
<guid>http://www.medgadget.com/archives/2008/08/the_shangring_circumcision_device.html</guid>
<category>Pediatrics</category>
<pubDate>Wed, 06 Aug 2008 00:00:00 -0800</pubDate>
</item>
<item>
<title>CX50 Portable Ultrasound from Philips Goes On Sale</title>
<description><![CDATA[<p><img class="side" src="http://www.medgadget.com/archives/img/35422_CX50_oncart_LR.jpg" width="310" height="585" /><strong>Philips</strong> has announced the company's new portable ultrasound system, the CX50, which is the first mobile system that can be used with the company's proprietary PureWave transducers. These transducers are powered by a technology based on a new class of piezoelectric crystals, that exhibit "a quantum improvement in electromechanical coupling and strain levels. Compared to PZT ceramics, PureWave crystals are purer, more uniform, have lower losses, and are able to transfer energy with greater precision and efficiency." You can read more about PureWave <a href="http://www.medical.philips.com/us/products/ultrasound/technology/gi/purewave.asp">here</a>.</p>

<p>From the CX50 product page:</p>

<blockquote>Previously available only on our premium iE33 system, PureWave on the CX50 system allows you to get the clear images you need for confident diagnoses on a wide variety of patients, including the difficult-to-image.

<p>The CX50 system was designed for your critical study requirements. In addition to PureWave, its premium imaging and Doppler performance are possible because of its digital broadband beamformer and XRES technology. Easily perform advanced echo analysis with integrated QLAB and stress echo capability.</blockquote></p>

<p><img class="side" src="http://www.medgadget.com/archives/img/35422_CX50_ControlPanel_LR.jpg" width="310" height="409" /><blockquote>The CX50 is designed to make portable exams easy and efficient. One-button iSCAN automatically optimizes 2D and Doppler data for new levels of clarity for your portable studies. On-board QLAB provides advanced analysis capabilities during and after exams.</p>

<p>Portable exams are a challenge, and getting clear diagnostic data is complicated by many factors. Now you can have the image quality you need for the diagnostic confidence wherever you need it &ndash; take the CX50 to your patients. </p>

<p>The CX50 system can be used on a specially designed cart, hand carried to your patients, or packed in its special travel case for easy transport to remote destinations.  </blockquote></p>

<p><b>Press release:</b> <a href="http://www.medical.philips.com/main/news/content/file_1812.html">Philips new handheld ultrasound system offers premium image quality in a portable system</a></p>

<p><strong>Product page:</strong> <a href="http://www.medical.philips.com/main/products/ultrasound/cardiology/CX50/index.html">CX50 CompactXtreme Ultrasound System</a></p>]]></description>
<link>http://www.medgadget.com/archives/2008/08/cx50_portable_ultrasound_from_philips_goes_on_sale.html</link>
<guid>http://www.medgadget.com/archives/2008/08/cx50_portable_ultrasound_from_philips_goes_on_sale.html</guid>
<category>Anesthesiology</category>
<pubDate>Tue, 05 Aug 2008 12:45:48 -0800</pubDate>
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<item>
<title>PlasmaBlade System Gets FDA Go Ahead</title>
<description><![CDATA[<p><img class="bcntr" src="http://www.medgadget.com/archives/img/3533pl1.jpg"><br />
<strong>Peak Surgical</strong> is happy to announce that the FDA has 510(k) OK'ed to market the company's plasma scalpel system for use in general surgery, a device we reviewed back in May.  The system touts the precision of a standard scalpel and the cauterization abilities of the bovie, but without the accompanying burning of peripheral flesh and all the smoke.</p>

<p>The video below shows off the technology and demonstrates various cuts using the PlasmaBlade compared to scalpels and bovies.</p>

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<p><script type="text/javascript"><br />
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document.write(unescape("%3Cscript src='" + gaJsHost + "google-analytics.com/ga.js' type='text/javascript'%3E%3C/script%3E"));</p>

<p></script><script src="http://www.google-analytics.com/ga.js" type="text/javascript"></script><br />
<script type="text/javascript"><br />
var pageTracker = _gat._getTracker("UA-1606987-19");<br />
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<p><a href="http://www.peaksurgical.com/">Peak Surgical homepage...</a></p>

<p><b>Press release</b>: <a href="http://www.peaksurgical.com/news/press-releases/?i=147">PEAK Surgical Receives 510(k) Clearance to Market PEAK&reg; Surgery System for Use in General Surgery...</a></p>

<p><strong>Flashback:</strong> <a href="http://www.medgadget.com/archives/2008/05/peak_plasmablade.html">Peak PlasmaBlade Wants to Be The New Bovie</a></p>]]></description>
<link>http://www.medgadget.com/archives/2008/07/plasmablade_system_gets_fda_go_ahead.html</link>
<guid>http://www.medgadget.com/archives/2008/07/plasmablade_system_gets_fda_go_ahead.html</guid>
<category>Surgery</category>
<pubDate>Thu, 24 Jul 2008 09:53:33 -0800</pubDate>
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<item>
<title>Epocrates Rx Now on iPhone</title>
<description><![CDATA[<p><img class="side" src="http://www.medgadget.com/archives/img/epocrates_iphone.png" width="207" height="379" /><strong>Epocrates </strong>has announced that its free drug and formulary application, Epocrates Rx, is finally available for the iPhone through the iTunes store.  </p>

<p>Some of the features from the product page:</p>

<blockquote><li>Adult and pediatric dosing for FDA-approved and off-label indications</li>
<li>Black box warnings, contraindications, and cautions</li>
<li>Serious and common adverse reactions, and drug interactions organized by clinical category</li>
<li>Pill pictures within the drug monograph showing you and your patients exactly what each drug looks like</li>
<li>Safety and monitoring information, such as pregnancy risk categories, lactation safety ratings, monitoring parameters and therapeutic drug levels</li>
<li>Manufacturer information, approximate retail pricing, and FDA/DEA status</li>
<li>Pharmacology information, including metabolism, excretion (i.e., half-life), drug class, and mechanism of action</li>
<li>Notes section for your personal notes</li></blockquote>

<p><b>Press release</b>: <a href="http://www.marketwatch.com/news/story/epocrates-drug-formulary-application-apple/story.aspx?guid=%7B1C74FC9A-DE0C-424D-BAD6-BD706B236CF4%7D&amp;dist=hppr">Epocrates Drug and Formulary Application on Apple App Store</a></p>

<p><strong>Product page</strong>: <a href="http://www.epocrates.com/products/rx/iphone.html">Epocrates Rx for iPhone</a></p>]]></description>
<link>http://www.medgadget.com/archives/2008/07/epocrates_rx_now_on_iphone.html</link>
<guid>http://www.medgadget.com/archives/2008/07/epocrates_rx_now_on_iphone.html</guid>
<category>Medicine</category>
<pubDate>Mon, 14 Jul 2008 11:56:19 -0800</pubDate>
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<item>
<title>Artificial Mesh for Prevention of Post Operative Abdominal Wall Defects</title>
<description><![CDATA[<p><img class="bcntr" src="http://www.medgadget.com/archives/img/meshdevice.jpg" width="468" height="330" /><br />
Spanish clinicians have designed a new device, dubbed Laparomesh, for prevention of incisional hernias.  Made out of nondegradable silicon and polypropylene plastic, the device is meant to permanently stay in place and to provide multiplanal tissue anchoring. </p>

<p>From the announcement by European AlphaGalileo Foundation:</p>

<blockquote>...a research group from the University of Alcal&aacute; managed by Professor Juan Manuel Bell&oacute;n from the department of surgery of the UAH has developed and patented a new device to prevent the occurrence of incisional hernias. This prevention is carried out by the incorporation of prosthesis into the suture of the abdominal wall which is designed to increase the cohesive forces of the scar. The new design and concept of the prosthesis, named Laparomesh has the shape of a upside down T and is made with silicone and polypropylene, which are biomaterials that will not be absorbed by the body.

<p>The goal of the Laparomesh is to create a reinforcement much like a tendon in the linea alba that would efficiently consolidate the suture of the laparotomy and significantly reduce the cases of incisional hernias. Different to the other prostheses of its type, the design by Professor Bellon and his team is placed neither above nor below, but it encloses both apertures of the abdominal wall, attaching itself to the different anatomical planes by means of a polypropylene suture.</p>

<p>Professor Bell&oacute;n, stated that the current average number of cases of incisional hernias is around 15% to 20%, and it is estimated to reduce these numbers to 3%-4% using this newly patented mesh.</blockquote></p>

<p><strong>Press release:</strong> <a href="http://www.alphagalileo.org/index.cfm?ez_search=1&fuseaction=readrelease&releaseid=530139#resources" title="New patented prophylactic mesh for the repair of defects in the abdominal wall">New patented prophylactic mesh for the repair of defects in the abdominal wall...</a></p>

<p>Image caption: <em>T shaped prosthesis for the reinforcement of medium laparotomies 1. Vertical branch of the T. 2. Horizontal branch. 3 Silicon cover (peritoneum), 4. Union between polypropylene and the silicon (thermoseal or suture). (Credit: Image courtesy of University of Alcal)</em></p>]]></description>
<link>http://www.medgadget.com/archives/2008/06/artificial_mesh_for_abdominal_wall_defect_repair.html</link>
<guid>http://www.medgadget.com/archives/2008/06/artificial_mesh_for_abdominal_wall_defect_repair.html</guid>
<category>Ob/Gyn</category>
<pubDate>Tue, 17 Jun 2008 11:53:44 -0800</pubDate>
</item>
<item>
<title>The Third Install in the US of Aquilion ONE CT from Toshiba</title>
<description><![CDATA[<p><img alt="" class="bcntr" src="http://www.medgadget.com/archives/img/46455ct.jpg" width="468" height="326" /><br />
Toshiba's gargantuan dynamic volume system called AquilionONE, the device that features a coverage area of 320 detectors rows in addition to a respectable 650 lb table capacity, has now been installed at Beth Israel Deaconess Medical Center in Boston, according to a press release obtained by Medgadget. This is the third install of this device in the US. We first covered AquilionONE CT back in <a href="http://www.medgadget.com/archives/2007/11/aquilionone_ct_from_toshiba_cleared_by_fda.html">November 2007</a>, when it was first unveiled at the RSNA 2007 conference. So when two days ago we were all excited about <a href="http://www.medgadget.com/archives/2008/05/demand_is_high_for_brilliance_ict_a_256slice_ct_from_philips.html" title="Demand Is High for Brilliance iCT, a 256-Slice CT from Philips">high demand for 256-slice CT scanners</a>, we should have have kept a more proper perspective: the 320-slice system is also here to stay, albeit initially in smaller numbers. A representative for the company, tells Medgadget: "The Aquilion ONE has a coverage area of 320 detector rows, can capture actual organ movement (like blow flowing through the heart) and can image an entire organ in one gantry rotation.  Additionally, the Aquilion ONE can capture the heart in one heart beat."</p>

<p><img alt="" class="bcntr" src="http://www.medgadget.com/archives/img/46455ct1.jpg" width="468" height="267" /><br />
<center><em>Cardiac: Coronary artery bypass evaluation acquired using Aquilion ONE.</em></center></p>

<p>From the press release:</p>

<blockquote>As a testament to the growing demand to improve patient care while reducing healthcare costs, Toshiba America Medical Systems, Inc. has installed the Aquilion ONE&trade; dynamic volume CT system at Beth Israel Deaconess Medical Center, a teaching hospital of Harvard Medical School in Boston.

<p>&quot;In one of the country's leading medical teaching hospitals, we hope the Aquilion ONE's ability to image an entire organ and show function for the first time will mean faster, more accurate diagnosis, better patient outcomes and ultimately lower healthcare costs for our patients,&quot; explained Dr. Vassilios D. Raptopoulos, interim radiologist-in-chief, Department of Radiology and director, CT services, Beth Israel Deaconess Medical Center. &quot;We are grateful to be one of the first teaching hospitals in the United States using this advanced technology.&quot;</p>

<p>Toshiba's Aquilion ONE dynamic volume CT system utilizes 320 ultra-high resolution detector rows (0.5 mm in width) to image an entire organ in a single gantry rotation. The result is unparalleled in diagnostic imaging today and produces a 4D clinical video showing up to 16 cm of anatomical coverage, enough to capture the entire brain or heart, and show its movement such as blood flow.</p>

<p><img class="bside" src="http://www.medgadget.com/archives/img/toshiba_MRI2.jpg" width="277" height="275" />&quot;The Aquilion ONE has the potential to provide a single, comprehensive exam that can replace a variety of duplicative and invasive procedures,&quot; added Dr. Raptopoulos. &quot;Its versatility and ability to diagnose disease fast will be used within our radiology department to detect and treat life-threatening conditions, including cancer, heart disease, stroke and other neurovascular conditions.&quot;</blockquote></p>

<p>To get impressed, head on to the <a href="http://www.medical.toshiba.com/products/ct/DynamicVolume/ClinicalCardiac01.aspx" title="Aquilion ONE: Clinical Movie Theatre">Aquilion ONE Clinical Movie Theatre</a> at Toshiba, and check out some of the studies presented there...</p>

<p><strong>Product page:</strong> <a href="http://www.medical.toshiba.com/Products/CT/DynamicVolume/" title="Aquilion ONE">Aquilion ONE...</a></p>]]></description>
<link>http://www.medgadget.com/archives/2008/05/the_third_install_of_aquilion_one_ct_from_toshiba_in_the_us.html</link>
<guid>http://www.medgadget.com/archives/2008/05/the_third_install_of_aquilion_one_ct_from_toshiba_in_the_us.html</guid>
<category>Radiology</category>
<pubDate>Wed, 21 May 2008 13:11:49 -0800</pubDate>
</item>
<item>
<title>Demand Is High for Brilliance iCT, a 256-Slice CT from Philips</title>
<description><![CDATA[<p><img alt="" class="cntr" src="http://www.medgadget.com/archives/img/5453ct1.jpg" width="468" height="390" /><br />
It seems just like it was yesterday when we were covering <a href="http://medgadget.com/archives/2005/04/brilliance_64sl.html"> 64 slice CT scanners</a> as the best and the latest thing in cardiac diagnostics. But technology is moving forward, and the demand for monstrous 256-slice CT scanners is quite high. Readers might recall our coverage of <a href="http://medgadget.com/archives/2007/03/aquilion_beta_2.html" title="Toshiba's Aquilion beta 256, the world's first 256-slice CT scanner">Toshiba's Aquilion beta 256</a>, the world's first 256-slice CT scanner. <strong>Philips Electronics</strong> is now reporting that their 256 scanner, Brilliance iCT, unveiled last November, is now installed in 5 medical centers across  the world (MetroHealth Medical Center in Cleveland, Methodist Hospital in Indianapolis, Carmel Medical Center in Haifa, Israel, in Washington Hospital Center in Washington, D.C., and in Lenox Hill Hospital in NYC), with 50 (<strong>!</strong>) more systems to be installed by the end of 2008.</p>

<p>Here's what Philips says about its Brilliance iCT with Essence technology:</p>

<p><img alt="" class="bside" src="http://www.medgadget.com/archives/img/5453ct2.jpg" width="300" height="300" /><blockquote>... customers tout the system&rsquo;s ability to provide greater dimension and depth across a range of clinical areas such as whole brain perfusion, cardiac CT with Step &amp; Shoot technology that images the heart in two beats while reducing dose, head and neck angiography, full field of view lung studies, virtual colonoscopy and abdominal and pelvic imaging. Brilliance iCT with Essence technology offers an impressive combination of speed, power and coverage to improve image quality while incorporating the latest dose reduction technology. Overall patient experience is improved through shorter scan times.</p>

<p>In addition to the 256 slice intelligent Brilliance iCT, the Brilliance 64-channel configuration is also designed with Essence technology. Unique and proprietary to Philips, Essence technology brings advances to the X-ray tube, detector system, and reconstruction engine while offering a scalable platform to enhance image quality and dose efficiencies.</p>

<p>&ldquo;With Brilliance iCT, the superb image quality aids our clinicians in the diagnosis of complicated health conditions,&rdquo; said Dr. Nathan Peled, head department of radiology of Carmel Medical Center in Haifa, Israel. &ldquo;The system has delivered increased rotation speeds and improved image quality and clinical performance for diagnostic confidence in routine and advanced radiological imaging.&rdquo;</blockquote></p>

<p>Below you can find the technical backgrounder paper distributed by the company:</p>

<center><object codebase="http://download.macromedia.com/pub/shockwave/cabs/flash/swflash.cab#version=9,0,0,0" id="-609453148" name="-609453148" classid="clsid:d27cdb6e-ae6d-11cf-96b8-444553540000" align="middle" height="500" width="468"> <param name="movie" value="http://documents.scribd.com/ScribdViewer.swf?document_id=3025237&access_key=key-23itzmrn1hu8znbjmfkc&page=1&version=1"> <param name="quality" value="high"> <param name="play" value="true"> <param name="loop" value="true"> <param name="scale" value="showall"> <param name="wmode" value="opaque"> <param name="devicefont" value="false"> <param name="bgcolor" value="#ffffff"> <param name="menu" value="true"> <param name="allowFullScreen" value="true"> <param name="allowScriptAccess" value="always"> <param name="salign" value=""> <embed src="http://documents.scribd.com/ScribdViewer.swf?document_id=3025237&access_key=key-23itzmrn1hu8znbjmfkc&page=1&version=1" quality="high" pluginspage="http://www.macromedia.com/go/getflashplayer" play="true" loop="true" scale="showall" wmode="opaque" devicefont="false" bgcolor="#ffffff" name="-609453148_object" menu="true" allowfullscreen="true" allowscriptaccess="always" salign="" type="application/x-shockwave-flash" align="middle" height="500" width="468"></embed> </object><div style="font-size:10px;text-align:center;width:468"><a href="http://www.scribd.com/doc/3025237/brilliance-iCT-technical-backgrounder">brilliance iCT technical backgrounder</a> - <a href="http://www.scribd.com/upload">Upload a doc</a></div><div style="display:none"> Read this doc on Scribd: <a href="http://www.scribd.com/doc/3025237/brilliance-iCT-technical-backgrounder">brilliance iCT technical backgrounder</a> </div> </center>

<p><strong>Product page:</strong> <a href="http://www.medical.philips.com/main/products/ct/products/CT_brilliance_iCT/index.asp" title="Brilliance iCT">Brilliance iCT...</a></p>

<p><strong>Press release:</strong> <a href="http://www.medical.philips.com/main/news/content/file_1755.html" title="Philips accelerates plans to install Brilliance iCT around the world">Philips accelerates plans to install Brilliance iCT around the world...</a></p>]]></description>
<link>http://www.medgadget.com/archives/2008/05/demand_is_high_for_brilliance_ict_a_256slice_ct_from_philips.html</link>
<guid>http://www.medgadget.com/archives/2008/05/demand_is_high_for_brilliance_ict_a_256slice_ct_from_philips.html</guid>
<category>Radiology</category>
<pubDate>Mon, 19 May 2008 14:34:41 -0800</pubDate>
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<item>
<title>Tengion is Hopeful as Its Full Size Neo-Bladders Do Well in Animal Models</title>
<description><![CDATA[<p><img class="bcntr" src="http://www.medgadget.com/archives/img/tengion_bladder_growing.jpg" width="450" height="461" /><br />
<strong>Tengion</strong>, a company out of East Norriton, PA, has <strong>successfully grown full size replacement bladders</strong> in large mammal models, helping pave the way for the company to receive FDA clearance to initiate clinical trials on humans in 2009. The company says that the results from a preclinical trial show that its product, known as Tengion Neo-Bladder Replacement&trade;, is structurally similar to native bladders by six months.</p>

<p>Here's what the company says in its press release about the long term morphology and performance of Tengion Neo-Bladder Replacement&trade;:</p>

<blockquote>The preclinical study presented at AUA <em>[the Annual Meeting of the American Urological Association (AUA) in Orlando, Florida --ed.] </em>was a six-month, single-arm study to evaluate the application of Tengion's technology to regenerate an entire urinary bladder. Neo-Bladder Replacements were produced from autologous bladder cells seeded onto a biodegradable scaffold and were then surgically implanted into 23 large mammals.

<p>Study results show that:</p>

<p><li>Tengion's Neo-Bladder Replacement was able to regenerate an entire urinary bladder within six months after implantation</li><br />
<li>The regenerated bladder demonstrated near-baseline capacity and cystography by six months after implantation</li><br />
<li>The regenerated bladder wall structure consisted of three layers: urothelium, muscle, and serosa by approximately two months after implantation</li><br />
<li>The regenerated bladder wall showed near native pharmacological and electrophysiological functional responses by six months after implantation</li></blockquote></p>

<p><strong>Press release:</strong> <a href="http://www.tengion.com/news/press/20080519.cfm" title="Preclinical Data Demonstrate Ability to Regenerate an Entire Bladder with Tengion Neo-Bladder Replacement™">Preclinical Data Demonstrate Ability to Regenerate an Entire Bladder with Tengion Neo-Bladder Replacement&trade; ...</a></p>

<p><a href="http://www.tengion.com/technology/index.cfm">Tengion technology page...</a></p>]]></description>
<link>http://www.medgadget.com/archives/2008/05/full_size_bladders_regenerated_in_mammals.html</link>
<guid>http://www.medgadget.com/archives/2008/05/full_size_bladders_regenerated_in_mammals.html</guid>
<category>Urology</category>
<pubDate>Mon, 19 May 2008 12:10:21 -0800</pubDate>
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<title>Urine Runs Through It</title>
<description><![CDATA[<p><img alt="" class="bside" src="http://www.medgadget.com/archives/img/54345pr.jpg" width="250" height="364" />Here's an interesting idea. The Netherlands Organization for Scientific Research (NWO) is reporting that a Dutch investigator Tim Idzenga believes that a microphone attached to perineum in men can listen to changes in the sound of flowing urine during urination, potentially detecting hissing tones of benign prostatic hyperplasia. He even wants to commercialize the idea to develop a diagnostic system:</p>

<blockquote>Elder men with voiding symptoms, such as a weak urinary stream and frequent voiding, often suffer from an enlarged prostate, clinically known as 'Benign Prostatic Enlargement' (BPE). However, a weak urinary stream and frequent voiding can also be caused by a weak bladder, for which a prostate operation does not help.

<p>If BPE is suspected in a patient, the bladder pressure during voiding is measured using a catheter inserted into the bladder via the urethra. The urinary flow is simultaneously recorded. This investigation is time-consuming, painful and carries a risk of infection. On top of this, it is not carried out in all patients with BPE symptoms. Consequently, there is a need for a simple, painless measurement method for determining the resistance of the urethra and its location.</p>

<p>Tim Idzenga came up with the idea of using the sound produced by the urinary flow in the urethra as a measure of the urethral resistance. He performed the measurement by placing a microphone against the perineum, between the scrotum and anus. The frequency spectrum of the sound was found to correlate with the narrowing of the urethra. The degree of narrowing can therefore be determined from the recorded urinary sound.</p>

<p>A patent for this invention is being applied for in cooperation with the company IQ+ Medical BV. The method will be tested at the urology outpatient clinic of the Erasmus MC in Rotterdam. Besides the standard method, patients with voiding symptoms will also be asked to urinate with a microphone against the perineum. </blockquote></p>

<p><strong>NWO press release:</strong> <a href="http://www.nwo.nl/nwohome.nsf/pages/NWOA_7DLJ6L_Eng" title="NWO - Listening to the urinary stream">Listening to the urinary stream...</a></p>

<p><strong>Image credit</strong>: Wellcome images: <a href="http://images.wellcome.ac.uk/indexplus/result.html?_IXFIRST_=22&_IXSS_=_IXFIRST_%3d1%26_IXINITSR_%3dy%26_IXACTION_%3dquery%26IXFROM%3d%26IXTO%3d%26_IXrescount%3d89%26_IXMAXHITS_%3d250%26%2524%2bwith%2bwi_sfgu%2bis%2bY%3d%252e%26%252asform%3dwellcome%252dimages%26%2524%253dsort%3dsort%2bsortexpr%2bimage_sort%26_IXSESSION_%3dtLiXe6ikIhQ%26c%3d%2522historical%2bimages%2522%2bOR%2b%2522contemporary%2bimages%2522%2bOR%2b%2522corporate%2bimages%2522%2bOR%2b%2522contemporary%2bclinical%2bimages%2522%26i_num%3d%26_IXshc%3dy%26i_pre%3d%26%2524%253ds%3dprostate%26_IXFPFX_%3dtemplates%252ft%26%2524%253dsi%3dtext%26t%3d%26w%3d&_IXACTION_=query&_IXMAXHITS_=1&_IXSR_=U_k9yEUCbMu&_IXSPFX_=templates%2ft&_IXFPFX_=templates%2ft" title="Anatomy of the prostate. Colour artwork.">Anatomy of the prostate. Colour artwork....</a><br />
 <br />
(hat tip: <a href="http://mtbeurope.info/news/2008/805014.htm" title="MTB Europe - Microphone replaces catheter for detecting benign prostatic enlargement">MTB Europe</a>)</p>]]></description>
<link>http://www.medgadget.com/archives/2008/05/urine_runs_through_it.html</link>
<guid>http://www.medgadget.com/archives/2008/05/urine_runs_through_it.html</guid>
<category>Urology</category>
<pubDate>Fri, 16 May 2008 09:09:58 -0800</pubDate>
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