Medicine Archive

Thursday, July 2, 2009

Device Captures Endothelial Progenitor Cells; May Help Detect Vascular Disease Early


Researchers from Northeastern University and Harvard Medical School have developed a miniature microfluidic device that is capable of capturing endothelial progenitor cells (EPCs) from the bloodstream, in a sample of only 200 microliters of blood. Because endothelial progenitor cells move towards injuries within blood vessels, detecting their presence can lead to a diagnostic system for various vascular diseases.

From the abstract:

The surface of a variable-shear-stress microfluidic device was conjugated with 6 different antibodies [anti-CD34, -CD31, -vascular endothelial growth factor receptor-2 (VEGFR-2), -CD146, -CD45, and -von Willebrand factor (vWF)] designed to match the surface antigens on ovine peripheral blood-derived EPCs. Microfluidic analysis showed a shear-stress-dependent decrease in EPC adhesion on attached surface antigens. EPCs exhibited increased adhesion to antibodies against CD34, VEGFR-2, CD31, and CD146 compared to CD45, consistent with their endothelial cell-specific surface profile, when exposed to a minimum shear stress of 1.47 dyn/cm(2). Bone-marrow-derived mesenchymal stem cells and artery-derived endothelial and smooth muscle cells were used to demonstrate the specificity of the EPC microfluidic device. Coated hematopoietic specific-surface (CD45) and granular vWF antibodies, as well as uncoated bare glass and substrate (1% BSA), were utilized as controls. Microfluidic devices have been developed as an EPC capture platform using immobilized antibodies targeted as EPC surface antigens.

Abstract in FASEB Journal: Development of microfluidics as endothelial progenitor cell capture technology for cardiovascular tissue engineering and diagnostic medicine

(hat tip: Gizmag)

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Thursday, July 2, 2009

Nephros' Dual Stage Ultrafilter System Guarantees Clean Fluids for Dialysis Machines

Nephros, Inc., out of River Edge, New Jersey, received FDA approval for the firm's Dual Stage Ultrafilter system. The device is designed to provide redundant filtration for purifying of dialysate fluid and bicarbonate solution.

From the product page:

The Nephros DSU has a 0.005 micron filter pore size designed to remove a broad spectrum of bacteria, viral agents and biological toxins. These toxins include salmonella, hepatitis, HIV, Ebola viruses, legionella, fungi and e-coli. The DSU removes these harmful substances more effectively than other microwater filters currently on the market.

The Nephros DSU's unique design and materials ensure high flow rates and long life. The true redundant design provides the highest confidence in filter integrity and performance. The Nephros DSU is a truly cost effective, simple and compact means to reliably produce on-site ultrapure water where you need it, when you need it.

Product page: Dual Stage Ultrafilter...

Nephros DSU brochure...

Press release: Nephros Receives 510k Approval for Dual Stage Ultrafilters...

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Wednesday, July 1, 2009

If Paris Hilton Had a Gas Mask


Yanko Design blog is featuring the work of Elijah Stillson who offers a new design idea for a respirator. Although, when wearing this thing, one would be the most attractive person in a crowd of evacuees, let's hope the device can seal around the face to stay tight with this design.

Link: Respirator Mask Design by Elijah Stillson

(hat tip: Gizmodo)

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Brainsway to Test TMS for Smoking Cessation

Brainsway Ltd. out of Jerusalem, Israel, a company we've been covering over the last few years, has received local approval to conduct clinical trials of its deep transcranial magnetic stimulation (TMS) as an aid in quitting smoking. The drastic approach is to be tested on about 100 lung cancer patients that have not been able to quit using other methods.

More from Globes Online...

Flashbacks: Magnetic Brain Stimulation for Cocaine Addiction, Multiple Sclerosis?; Positive Results Reported for Deep TMS H System For Depression; Deep TMS Technology by Brainsway

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Monday, June 29, 2009

ecg@home Personal ECG Monitoring Helps Clinicians Stay On Top of Patient Status


HealthFrontier out of Branchburg, New Jersey teamed up with et medical devices SpA, a Vignate, Italy firm, to create a simple remote wireless ECG monitoring device. The ecg@home features two thumb electrodes (i.e. the standard I lead), and a wireless transmission of the data out to a central server via Bluetooth, USB, or a cell phone network. In order for the device to work, the company says the patient needs to rub his fingers with the K2 solution for better contact

Features from the product page:

* Monitor the patient over the long-term with a substantially decreased impact on quality of life.
* Catch events that only appear irregularly, with the secondary benefit that patients can now feel at ease that they will be able to capture their worrisome cardiac events
* Keep care of the patient in-house, and it allow them perform their own interpretation and analysis of the ECG strips if they so desire, or use an in-house technician if one is available.
* If the physician does not desire to interpret the readings, a third-party service can send the analyzed scans minutes after the reading is taken.
* Monitor the effects of changes in medication
* Access all the patient’s historical ECG readings with the click of a mouse through the RHMS, eliminating the need to search through a library of paper-chart printouts.

healthb.jpg
* Take ECG readings with far more speed than the 12-lead option
* Through the RHSM, readings can be quickly interpreted either on-site or by a third party scanning service, and returned to the originating facility in minutes.
* Determine the impact and effectiveness of the existing therapy regimen, and adjust regimen.
* Use the analyzed reading in deciding whether the patient requires emergency care.
* This solution offers tremendous saving potential by enabling the decision-maker keep patients out of the hospital when their conditions are non-critical, and to provide prompt medical attention when serious medical conditions are present.

Product page: ecg@home

More from The Medical Quack...

Press release: HealthFrontier Introduces New Innovation in Web-Based Remote Health Monitoring Technology

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Thursday, June 25, 2009

Piix Wireless Home Cardiac Monitoring to Undergo Randomized Trial


Corventis, a maker of wireless CHF monitoring devices that measure heart rate, heart rate variability, respiratory rate, fluid status and activity, and West Wireless Health Institute, a research organization promoting wireless technology use in medicine, have teamed up to conduct multi center clinical trials of the Piix device, a monitoring gadget we have profiled before.

From the press release:

Corventis' remote monitoring wireless system was approved by the FDA in February 2009, which sets up the potential for a multicenter, randomized clinical trial. The trial will be spearheaded by the West Wireless Health Institute and led by Dr. Eric J. Topol, the Institute's chief medical officer. Dr. Topol is also chief academic officer at Scripps Health and holder of the Gary and Mary West Chair of Innovative Medicine.

Participation in the pivotal randomized trial with WWHI and Corventis will be offered to the sites supported by the National Institutes of Health Clinical and Translational Science Award (CTSA) National Consortium, which consists of 38 of the most prestigious academic medical centers in the United States. The trial is designed to clinically validate remote wireless monitoring technology in proactively managing heart failure patients and reducing hospital readmissions.

Press release: West Wireless Health Institute Teams with Corventis for its First Multicenter, Randomized Clinical Trial...

Links: West Wireless Health Institute; Corventis technology...

Flashback: PiiX Monitors for Signs of Decompensated Heart Failure...

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Wednesday, June 24, 2009

Improve Your Ultrasound Skills With New SonoSite iPhone App


SonoSite has released an iPhone application, called SonoAccess™, to help clinicians improve their analytical and performance skills when using ultrasound. With the help of instructional videos and an accompanying image gallery, you can improve on your echo knowledge while on your train ride to work.

Features:

Scanning Technique Videos are designed to provide expert techniques and tips for point-of-care ultrasound applications.

Video Case Studies provide an in-depth look into specific cases that you may encounter in your practice.

Clinical Image Gallery is designed to give you a look at expert ultrasound images for anatomy recognition and as a quick comparative reference for you to compare your results to.

Quick-Start Guides are abbreviated user manuals designed to give new SonoSite users a digital roadmap of their system's controls and features to help navigate the user interface.

The Reimbursement Guides are designed to provide general coverage and payment information for diagnostic ultrasound and ultrasound-guided procedures so you have accurate coding and billing information.

The SonoAccess News Feed keeps you up-to-date on the latest SonoSite news.

Watch video here demonstrating the app...

Product page: SonoAccess™ Ultrasound iPhone App

Download link @ AppStore...

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Tuesday, June 23, 2009

Lung Flute Helps to Get The Sputum Out

mylarre3423.jpg
Chronic obstructive pulmonary disease, chronic bronchitis, and a number of other pulmonary disorders make it difficult for the sufferers to cough out built up mucus. A simple medical device called the Lung Flute from Medical Acoustics (Buffalo, New York) has recently been submitted to the FDA for approval as a new therapeutic tool. Essentially a plastic tube with a reed inside that waves about when blown at, the system creates sound vibrations that supposedly help dislodge mucus throughout the pulmonary tree.

From the press release:

The application follows the recent successful completion of a clinical trial at the University at Buffalo (SUNY) and the Western New York VA Medical Center. The clinical trial, led by principal investigator Sanjay Sethi MD, was designed to demonstrate the safety and effectiveness of the Therapeutic Lung Flute®. The trial was completed successfully with the Lung Flute® meeting all primary and secondary endpoints among patients with chronic obstructive pulmonary disease (COPD) with chronic bronchitis. This simple, hand-held, reusable therapeutic device supplements the patient’s natural mucus clearing system by introducing low frequency sound waves into the lungs.

Here's video demonstrating the use of the Lung Flute:

Product page: Lung Flute...

Press release: Medical Acoustics Files Application with FDA for 510(k) Clearance of Therapeutic Lung Flute...

Flashback: The Lung Flute Cleared by FDA for Sputum Induction...

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Monday, June 22, 2009

Bronchoscopic Biologic Lung Volume Reduction (BLVR) System from Aeris Therapeutics Aims on Emphysema

The market for technologies designed to treat emphysema and its symptoms is heating up, according to the experts at the Millennium Research Group. The "medical technology market intelligence" company believes that there is a number of products that are working through the clinical trials that are expected to receive FDA approval sometimes in the next five to ten years. One potential treatment is the Biologic Lung Volume Reduction (BLVR) system from Aeris Therapeutics (Woburn, MA). The company's system aims to slowly collapse diseased parts of the lungs through bronchoscopically delivered specialized injections ("proprietary mixture of drugs and biologics"), reducing the organ in size and improving the ventilation/perfusion relationships in patients with severe emphysema. As any medical student knows, improvement in a V/Q mismatch means improvement in oxygenation, and improvement in symptoms.

From the product page:

With BLVR, a physician uses a bronchoscope to direct treatment to the most damaged areas of the patient’s lungs. The treatment delivers a precisely proportioned proprietary mixture of drugs and biologics which, when combined at the treatment site, form a bioabsorbable gel. The gel is comprised of clotting proteins that deliver the treatment, an antibiotic to prevent infection and drugs designed to remodel damaged areas of the lungs—actually using the body’s natural scar formation response to permanently collapse the diseased areas. This reduction in lung volume creates more space for adjacent healthier parts of the lungs to function more effectively. The gel polymerizes quickly after delivery so it does not migrate to non-targeted areas of the lung. In addition, since no implant remains in the body, it obviates the risks of long-term infection, implant migration or tissue reaction.

Aeris Therapeutics has completed Phase 2 clinical trials of BLVR. Results indicate that BLVR is well tolerated and is associated with significant improvements in breathing function, symptoms and quality of life.

System info page: Biologic Lung Volume Reduction System

Press release: Broncus Technologies' Exhale Stent and Other New Devices to Prompt Robust Growth In Emphysema Treatment Market, According to Millennium Research Group

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Friday, June 19, 2009

Voice Activated SonoSite Ultrasound System Keeps Hands Free to Perform Procedures


SonoSite just released their SonoRemote for controlling the company's M-Turbo and S Series ultrasounds during interventional procedures like joint injections or central line placements. In addition to traditional style buttons, the remote control features voice recognition and can be programmed to understand commands in any language. So now you can hold the probe in one hand and the syringe in the other, and not have to fiddle with reaching over to the unit to take snapshots or change parameters.

  • Voice or touch activated

  • Programmable to your voice and language

  • Adjust system controls from a radius of 10 meters

  • No need to break the sterile field

  • Drop-tested to 3 feet

  • Works with M-Turbo® and S Series™
  • Press release: SonoSite Begins Customer Shipments Of Ultrasound Remote Control

    Product page: SonoRemote

    Flashbacks: M-Turbo™: New Portable Ultrasound from SonoSite ; SonoSite S-ICU™ Ultrasound Tool; S-Nerve™ from SonoSite; The SonoSite® MicroMaxx™; Titan

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    Glucose Buddy Helps to Watch Glucose Levels Over Time


    The Glucose Buddy is a simple iPhone application from MYLEstone Health developed fpr diabetics to make sugar level tracking easy and convenient. The patient enters regular readings from a personal glucometer into the iPhone app, and the system creates charts online when the data is synced to the PC.

    Features from the product page:

  • SYNCHRONIZATION BETWEEN DESKTOP AND IPHONE (free Premium Member acct)

    -Tap “Settings” and then “Synchronize” within App to synchronize entries to your online account


  • PRINT DATA ONLINE

  • FULL BACKUP (no more .csv cluttered Emails)

  • POWERFUL GRAPHING (e.g. graph avg ‘out of bed’ BG)

  • CORRELATION ANALYSIS (e.g. recognize BG trends by carb intake or time of day)

  • DATA PARAMETERS (e.g. set BG range and see how often you test within it)

  • WINDOWS & MAC COMPATIBLE
  • Product page: Glucose Buddy...

    Download @ iTunes...

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    SomnoDent MAS Helps Open Airway for OSA

    SomnoMed out of Crows Nest, Australia has been showing off its SomnoDent MAS device for obstructive sleep apnea at Sleep 2009 in Seattle this week. Worn while sleeping, the MAS is two custom shaped acrylic plates connected to each other, that are fitted over the teeth by a dentist, that force the lower jaw a bit forward. In other words, the device delivers what anesthesiologists call the "Jaw Thrust."

    Features:

  • A streamlined design with minimal bulk, which maximizes the size of the lingual space and reduces gagging.
  • An excellent fit in both upper and lower arches.
  • The unique design provides anterior and posterior contact, which provides a stable occlusion and prevents tooth movement and minimises termpero-mandibular joint discomfort and injury caused by bruxing.
  • The MAS is constructed in two separate pieces that allow patients to open and close their mouths. This allows clear speech, yawning and drinking without requiring the patient to remove the appliance. The ability to communicate clearly while wearing the device is particularly appreciated by patients and their partners.
  • The small form factor of the MAS and absence of anterior retaining mechanism helps patients sleep with their mouths closed. This minimises excessive salivation, dribbling, dry mouth and other common side-effects from wearing oral appliances.
  • The high-quality fit of the SomnoDent® MAS provides excellent levels of retention and ensures that there is limited to no damage to existing teeth, crowns or bridgework. Additionally, patients can titrate the device (if required) and it is easy to clean and disinfect. While it is exceptionally durable, its acrylic construction allows it to be easily repaired.
  • The device is titratable and allows for each individual patient's optimal protrusion position to be found. One that is both effective and comfortable to the patient.

  • Product page: SomnoDent® MAS

    (hat tip: ProactiveInvestors)

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    Wednesday, June 17, 2009

    HyGreen Active Sensor Network Makes Sure Hands Are Kept Clean


    Even though a proper and frequent hand washing in healthcare and food service industries is a strict requirement, it is often too easily ignored. On top of it, monitoring the compliance is obviously lacking. But the change is in the air. A new compliance monitoring system that uses sensors to smell the presence of soap on clinicians' hands has been developed at the University of Florida. Coupling RFID technology to keep an eye of who washed their hands where and when, the system lets doctors and nurses know if they need a refresher, while the management keeps tabs on overall facility cleanliness.

    The trademarked system, called HyGreen, logs, down to the second, the frequency of hand cleaning and contact with patients in a database that clinical supervisors can review immediately.

    This is the first system that enables real-time monitoring of hand washing.

    HyGreen is now being tested in the Neuro Intensive Care Unit at Shands at UF medical center, and will be presented at the annual meeting of the Association for Professionals in Infection Control and Epidemiology June 6 to June 9 in Fort Lauderdale, Fla.

    Here’s how it works: The health-care worker squirts sanitizer gel or soap into his or her hand before passing it under a wall-mounted sensor. A wireless signal from a badge worn by the worker activates a green light on the hand-washing sensor. When the worker enters a patient room, a monitor near the bed detects the status of the badge, and flashes green if the person has clean hands. If the person has not washed, or too much time has passed between washing and approaching the patient, the badge will give a gentle “reminder” vibration.

    Video from Xhale, Inc, the company marketing HyGreen:

    Screenshots of the reporting system can be found here...

    Press release: Soap-sniffing technology encourages hand washing to reduce infections, save money...

    Product page: HyGreen...

    Product brochure: HyGreen...

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    OXO Applies Firm's Design Skills to Medical Device Development


    Patients with rheumatoid arthritis and other debilitative hand conditions, are occasionally prescribed medications that have to be injected, either intramuscularly or intravenously. Because their joints can suffer from severe pain or movement restrictions, it is often difficult for patients to do their own injections. UCB, the Belgian pharmaceutical firm, must have noticed the big market for OXO rubber gripped kitchen tools among patients with arthritis, and worked together with OXO to develop a new syringe. Having just received FDA approval for Cimzia (certolizumab pegol) to treat rheumatoid arthritis, UCB is now making the drug available in the new prefilled syringes.

    Features of the new syringe:

  • Easy to grip wide flange (finger grips) - soft, non-slip grip allows patients to hold the syringe steady using various grip positions.
  • Easy to remove needle cover - rounded finger loop for easy removal of needle cover; flared needle cap designed to reduce needle pricks due to recoil.
  • Easy to push syringe plunger - large and soft thumb pad for patients to push the plunger.
  • Easy to read syringe barrel - magnified barrel helps ensure patients receive entire dose as they can see the medicine inside and know when they have injected all of it.
  • Easy to grip elliptical barrel - elliptical barrel for patients to grip and helps prevent slippage during patient handling.
  • Easy to open packaging - the cover with a rounded corner uses Velcro® for easy opening and resealing; large, easy-to-read directions and clear visuals instruct patients how to use the pack and administer/inject Cimzia®; and lastly, the plastic housing inside with a large finger recess allows patients to easily remove the syringe.
  • Press release: Partnership unites UCB with consumer product innovator OXO

    Product page...

    (hat tip: Core77)

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    Wednesday, June 10, 2009

    Masimo Unveils New Pulse Oximeter Rad-8

    masimorad8.jpg
    Masimo is releasing a new pulse oximeter Rad-8, a device touted to be especially useful at clinics that diagnose sleep disorders. Of course, it would seem there's no reason that the device can't be used for other relevant application, such as postoperative or intraoperative monitoring, ICU stays, or even regular floor stays. Rad-8 is essentially a slimmed down version of Masimo's popular line of pulse oximeters.

    From the press release:

    The new Rad-8 combines the unmatched sensitivity and specificity of Masimo SET® Measure-Through Motion and Low-Perfusion pulse oximetry—clinically-proven to reduce false alarms by over 90% and increase capture of true desaturation events by 98%—with enhanced functionality to help clinicians better capture, analyze, and report vital oxygen saturation, pulse rate, and perfusion data for improved sleep disorder detection.

    The superior fidelity of Masimo SET has been clinically-shown to outperform other pulse oximeters in the accurate identification and quantification of brief dips in oxygen saturation due to apneas and hypopneas—an important marker and measure of severity for Obstructive Sleep Apnea (OSA) diagnosis and treatment. In fact, previous research conducted at Montreal Children's Hospital in Quebec found that using a Masimo pulse oximeter with very short averaging time was not only more accurate in detecting true desaturation events, including brief dips in oxygen saturation as well as larger ones, but could also "significantly reduce workload and improve reliability of desaturation detection" over other pulse oximeters. Study findings confirmed that Masimo detected 98.6% of true desaturations, while the N-395 detected only 45.3%, leading researchers to conclude that "the sensitivity and motion artifact rejection characteristics of the Nellcor N-395 oximeter are not adequate for a pediatric sleep laboratory setting."2

    And, based on clinician input, Rad-8 now features an intuitive user-interface and easy menu navigation to save time and enable faster, easier set-up, and operation, while one-touch quick access buttons allow clinicians to engage special features in an instant. New user-selectable alarm settings make it quick and easy for clinicians to set and save configurations for specific patient monitoring needs and unique clinical applications. In addition, 72-hour trending, configurable Sleep and Home modes, and enhanced data collection/reporting compatibility make the new Rad-8 the ideal patient monitoring solution for sleep center, home, sub-acute, and transport applications.

    Press release: Masimo Debuts New Rad-8® Pulse Oximeter to Largest Gathering of Sleep Specialists from Around the World at SLEEP 2009

    Product page: Rad-8...

    Rad-8 data sheet (.pdf)...

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    Wednesday, June 3, 2009

    Bayer Releases New A1C Model for Diabetics

    Bayer Diabetes Care have finally released the updated version of the A1CNow SelfCheck home testing kit. Claiming to now produce more accurate A1C results that mimic lab testing, the unit comes packaged with two single-use cartridges.

    From the press release:

    A1CNow SELFCHECK, which is now available without a prescription and through leading online pharmacies, provides at-home results within five minutes, has an easy-to-use design and delivers lab accuracy. Measuring A1C levels is important for consistent diabetes management, as even a one-percent reduction in A1C reduces the risk of serious complications by 40 percent(1).

    At the healthcare provider's office patients can be tested with Bayer's A1CNow+ monitor, which provides results within five minutes, enabling physicians to evaluate their patients' overall diabetes control and discuss lifestyle and treatment modifications during the appointment, rather than waiting for lab results a few days later. A1CNow SELFCHECK complements the healthcare provider-administered A1C test but is not intended to replace it or routine blood glucose testing. Bayer's A1CNow SELFCHECK, when used in conjunction with Bayer's CONTOUR(R) or BREEZE(R)2 blood glucose meters, may help patients achieve tighter control in managing their diabetes, and therefore may reduce longer term complications.

    More from DiabetesMine...

    Product page: A1CNow® SELFCHECK System

    $30 on preorder from Walgreens

    Press release: Bayer Diabetes Care Launches A1CNow(R) SELFCHECK, a New A1C Monitor for At-Home Use

    Flashback: A1CNow+® for Home HbA1c Monitoring

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    Tuesday, June 2, 2009

    Dual-Energy Computed Tomography Helps Spot Gout

    Diagnosing gout, a nasty disease involving swollen joints and often a good deal of pain, is difficult because the symptoms are often similar to various forms of arthritis. The definitive method of diagnosis is to draw fluid from a joint and test it for the presence of uric acid crystals. CT scanners have long been considered potentially useful as a non-invasive diagnostic modality, but their ability to help identify uric acid deposits has been limited. To overcome this, Canadian researchers decided to try using a new algorithm on the SOMATOM Definition dual energy CT (DECT) scanner from Siemens. Initial findings from the researchers show that the novel technique can provide radiologists with significant help in diagnosing gout, potentially avoiding aspirations for patients in the future.

    Siemens explains the findings:

    In collaboration with Siemens, Dr. Savvas Nicolaou, Director of Emergency Radiology at Vancouver General Hospital and Associate Professor at the University of British Columbia in Vancouver, and both his radiology and rheumatology colleagues developed a dual-energy algorithm for identifying uric acid deposits.

    The Canadian scientists used a SOMATOM Definition from Siemens for their trials. This system is the only CT scanner worldwide that features two X-ray tubes capable of simultaneously producing different energies. The team performed scans at different energies to determine the attenuation values of uric acid deposits. Siemens used this data to develop a new dual-energy protocol for gout that now can be used by any physician. The software algorithm used to detect gout via DECT is based on the realization that the CT values of uric acid deposits are lower, for instance, than those of calcium if scans are performed at different energies (80 and 140 kilovolts). Through color coding of the different attenuation values, it then becomes possible to recognize mono sodium urate crystals on the clinical CT image: The uric acid crystals indicating gout are, for example, color coded in red, while other bone formations and calcium are displayed in blue. The commercial version of the Siemens application is called Syngo DE Gout.

    In a further study, Dr. Nicolaou and his colleagues investigated whether DECT can be used reliably to confirm the presence of gout tophi, whether DECT is superior to the traditional clinical examination ie detecting subclinical urate deposits, and whether this modality can clarify cases of doubt as problem solving tool. Ten patients were recruited who already had been diagnosed with gout by means of joint puncture with aspiration of synovial fluid and 10 control patients that did not have gout clinically. The patient records of all patients were analyzed and all patients underwent a complete rheumatological examination and DECT. The evaluation of the DECT images was performed by two radiologists working independently of one another.

    This study showed that the DECT images of all patients proven to have gout yielded correspondingly positive findings in the aspirated joints. The DECT images of the control group all showed negative findings. "Our findings indicate that deposits of mono sodium urate crystals can be detected sub clinically more efficiently using DECT than with the traditional clinical examination," says Dr. Nicolaou. The fact is that more areas involved with gout were found overall per DECT than through the other clinical examination ,ie 200 sites with DECT versus 53 sites clinically, ie four times more foci were revealed with DECT(p < 0.05). Furthermore, it has become evident that DECT can detect the presence of gout in hands, wrists feet, ankles, knees significantly better than the traditional clinical examination. DECT did not achieve significantly better results in the detection of gout in the elbow.

    Full statement from Siemens: New diagnostic method for gout: Dual Energy Computed tomography instead of joint aspiration

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    Monday, June 1, 2009

    Design Concept for Monitoring of Diabetic Feet

    Amy Tenderich is profiling the runner-up for the DiabetesMine Design Challenge Grand Prize. The FOOTSAFE is a system to help detect early signs of inflammation on the soles of feet of diabetics via a special scanner and an touch screen interface system that can display high resolution images.

    Here's the video submitted for the design contest explaining how the FOOTSAFE would function:

    More at DiabetesMine...

    Flashbacks: ShoePod™ to Get Trials in the US; TempTouch for Foot Ulcer Detection

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    Thursday, May 28, 2009

    ViRob, a Cavities Crawler


    At the upcoming ILSI-Biomed Israel 2009 conference (June 15-17 in Tel Aviv), researchers from the Medical Robotics Laboratory at the Israel Institute of Technology (Technion) will be showing off a microrobot called ViRob, that has only a 1millimeter diameter and can crawl through vessels and cavities, when controlled by an external magnetic field. The big idea behind the ViRob device is that it can be used to deliver pharmaceutical payloads to precise locations or pull a microcatheter through tortuous terrain.

    fdgs4534.jpgHere's what organizers of ILSI-Biomed Israel 2009 conference tell Medgadget:

    Researchers are currently examining the possibility of using ViRob as a treatment for lung cancer—the world’s deadliest cancer. ViRob could assist in targeted drug delivery to lung tumors as well as take samples from different areas within the body. In addition, a number of these micro robots could simultaneously treat a variety of metastases. Researchers also plan to install additional equipment on the robot, including cameras, miniature tongs and other miniature equipment.

    ViRob measures 1 millimeter in diameter and 14 mm in its entirety was developed in the lab of Prof. Shoham in the Medical Robotics Laboratory at the Israel Institute of Technology. The robot moves using an external electromagnetic ignition system, stimulated by an electromagnetic field with frequency and volume that do not agitate the body, enabling it to maneuver in different spaces and surfaces within diverse viscous fluids. The vibration created by the magnetic field propels the robot forward, as the tiny arms protruding from a central body grip the vessel wall. A basic prototype of the ViRob, which can move as fast as 9 mm per second, has been developed thusfar.

    Link: ILSI-Biomed Israel 2009...

    White paper from Technion...

    A few videos below the fold demonstrating the ViRob:

    READ MORE...


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    » The FibroScan®: Noninvasive Proof that You Are Drinking too Much (January 9, 2007)

    » PulmoLife™ Spirometry Screener (January 9, 2007)

    » Dental Films and Osteoporosis (January 3, 2007)

    » GlucoMON®2 Wireless Glucose Meter (January 3, 2007)

    » Sea Slug Offers Clues to Parkinson's and Alzheimer's (January 2, 2007)

    » New Implantable Optical Glucose Sensor (December 28, 2006)

    » CAREt System (December 18, 2006)

    » Thomson Clinical Xpert (December 12, 2006)

    » Non-invasive Glucometry from Orsense Wins Award (December 7, 2006)

    » VivaGel™: Intravaginal STD Defense (November 30, 2006)

    » AmpliChip for Personalized Prescriptions (November 30, 2006)

    » Dean Kamen Talks Medgadgets (November 30, 2006)

    » Parafricta Fabric (November 29, 2006)

    » Bedside Sleep Laboratory (November 28, 2006)

    » XStrain™ Technology (November 21, 2006)

    » Tied in Knots over Umbilical Cord Blood Bank (November 20, 2006)

    » Constant Health Companion™ by ALR Technologies (November 17, 2006)

    » Positive Results from Trial of Rheos Baroreflex Hypertension Therapy (November 16, 2006)

    » Vivid e (November 14, 2006)

    » MediDive's Asthma Freedom Snorkel (November 13, 2006)

    » ZOLL R Series Defibrillator for Hospitals (November 13, 2006)

    » Duct Tape: Not a Medgadget (November 8, 2006)

    » Smoothing Sickle Cells (November 8, 2006)

    » Trojan HIV Offers Hope (November 7, 2006)

    » Conix One Inhaler Promises to Replace Needles (November 1, 2006)

    » Alzheimer's Blood Markers Identified (October 31, 2006)

    » Tri-virus-specific cytotoxic T lymphocytes Help Transplant Patients (October 27, 2006)

    » Implantable RFID Microchips to Monitor Blood Sugar (October 27, 2006)

    » Thinklabs ds32a Stethoscope with Electromagnetic Diaphragm (October 25, 2006)

    » Custom-Designed Anti-Microbial Peptides (October 20, 2006)

    » Spectrally Encoded Mini Endoscope (October 19, 2006)

    » OxyView™ (October 11, 2006)

    » MHM100 Personal ECG Monitor (October 11, 2006)

    » Magenstrasse, an Oral Medications' Highway (September 25, 2006)

    » Medwave's Fusion™ and Primo® (September 22, 2006)

    » Nanocrystalline, Silver Coated, Long-Term Dialysis Catheters by Spire (September 22, 2006)

    » MacArthur Foundation Grants: Lisa Griffith (September 21, 2006)

    » Nanobodies™ by Ablynx (September 18, 2006)

    » Nano-pores Meet Dialysis (September 13, 2006)

    » The Arctic Sun® (September 13, 2006)

    » Hoana PSA™ Technology (September 12, 2006)

    » Zargis Acoustic Cardioscan™ (September 12, 2006)

    » The Helping Hand™ from Bang & Olufsen (September 11, 2006)

    » The I-PORT™ (September 7, 2006)

    » The Intraject® System (August 31, 2006)

    » CDC: FluChip Performs Well (August 29, 2006)

    » The Med-eMonitor™ System (August 25, 2006)

    » LEDs, the Efficient Bug Killers (August 22, 2006)

    » Tricked-Out Stethoscopes (August 17, 2006)

    » GlucoPhone: A Diabetics' Cellphone (August 17, 2006)

    » RF-MicroChannel™ Technology (August 14, 2006)

    » BioBlower (August 3, 2006)

    » Nicotine Has Come a Long Way, Baby (August 3, 2006)

    » Bacterial Resistance? Medihoney to the Rescue! (August 1, 2006)

    » Definition of Medgadget Continues to Expand; Now Encompasses Water Spray (July 31, 2006)

    » FES Brings Hope for the Paralyzed at the Cleveland Clinic (July 19, 2006)

    » Guardian® REAL-Time System (July 18, 2006)

    » ICIS PocketPACS (July 17, 2006)

    » Chair-A-Table Reduces Accidental-A-Injuries (July 14, 2006)

    » A1CNow+® for Home HbA1c Monitoring (July 10, 2006)

    » ViagraRing: Always Within Reach (July 3, 2006)

    » The Dx-pH Measurement System™ for Sleep Reflux (June 27, 2006)

    » Pathformer: Better than a Hot Paper Clip (June 26, 2006)

    » New IV System, N-One, Seeks to Make Traditional IV N-Two (June 21, 2006)

    » Breathtaking Sexy Inhalers (June 20, 2006)

    » The Scout: A Noninvasive Screening for Type 2 Diabetes (June 19, 2006)

    » Glucon Reports Positive Results (June 19, 2006)

    » Device for Transplantation in Diabetes Shows Promise (June 16, 2006)

    » Another Contender in the Safety Syringe Arena (June 15, 2006)

    » Be Still, My Beating Heart (June 15, 2006)

    » Discovery VCT Installed (June 13, 2006)

    » Giving Robots a More Refined Sense of Touch (June 13, 2006)

    » Hemopurifier™ to Treat Infectious Disease (June 8, 2006)

    » Allient Dialysis Device Gets FDA Clearance (June 8, 2006)

    » Blood Sucking Bugs as Medgadgets for Primates (June 7, 2006)

    » The Rx Master (June 1, 2006)

    » Bluetooth Group Working on Medical Monitoring (May 30, 2006)

    » The Ppups: Plug and Play Ultrasound Probe System (May 25, 2006)

    » Enigmatic Cuban Therapy for Diabetic Foot Ulcers (May 18, 2006)

    » The Oridion BreathID® (May 16, 2006)

    » The Plasmer™ (May 11, 2006)

    » Screening for Side Effects, Sooner (May 11, 2006)

    » Do-It-Yourself Tylenol Flavors (May 4, 2006)

    » VeinViewer Shipped! (May 1, 2006)

    » The CereTom™ Mobile CT Scanner (April 28, 2006)

    » The Delphi IVantage™ Infusion Pump (April 27, 2006)

    » CrossJect Needle-free Injection System (April 26, 2006)

    » The Senographe® Essential Mammography System (April 24, 2006)

    » Luminous Beings Are We (April 24, 2006)

    » Scan2Knit (April 19, 2006)

    » OmniPod® Insulin Management System (April 13, 2006)

    » The pH.p Capsule (April 12, 2006)

    » The Medfusion™ 3500 Syringe Pump (April 10, 2006)

    » Syringe Buttons (April 6, 2006)

    » Anti-Aging Love With Sir2 (April 3, 2006)

    » The Fidelity 100 ECG System (March 30, 2006)

    » The NC-stat System for Non-Invasive Nerve Conduction Testing (March 20, 2006)

    » Special Delivery (March 20, 2006)

    » Freedom Isn't Free (But It's Almost Painless) (March 20, 2006)

    » Under Pressure (March 20, 2006)

    » AUDICOR Correlated Audioelectric Cardiography (March 17, 2006)

    » Matchmaker, Matchmaker (March 16, 2006)

    » Gag-Be-Gone (March 8, 2006)

    » Delcath System for Isolated Liver Chemo (February 23, 2006)

    » Device Companies Would Prefer You Didn't Use the "R" Word (February 15, 2006)

    » Faster Anemia Test Released (February 15, 2006)

    » The GlucoTrack™ (February 14, 2006)

    » Web Project to Help Scientists Combat Influenza (February 6, 2006)

    » The Alair® System for Bronchial Thermoplasty™ (February 2, 2006)

    » FDA to Improve Post-Approval Device Monitoring (January 24, 2006)

    » The SleepStrip® (January 23, 2006)

    » The Hydron Implant Technology (January 20, 2006)

    » Laughter Can Cure (January 19, 2006)

    » Handheld "Vein Finder" for Faster, More Accurate IVs (January 18, 2006)

    » Medtronic Personal Therapy Manager (PTM) (January 12, 2006)

    » Ultrafiltration May Be Practical Alternative to Diuretics (December 9, 2005)

    » Q-CPR™ Measurement and Feedback Talking Tool (December 2, 2005)

    » The Terason t3000™ Ultrasound System (December 1, 2005)

    » Keep Fat In Mind (November 30, 2005)

    » The SonoSite® MicroMaxx™ (November 29, 2005)

    » Somatom Definition: The First Dual Source CT (November 21, 2005)

    » Diabetes, Discreetly (November 18, 2005)

    » Bionicare Electrical Stimulator Shows Promising Arthitis Results (November 17, 2005)

    » The Slurry Fury (November 15, 2005)

    » EKGuard (November 11, 2005)

    » Prevent Oral Cancer With Mouthwash (November 8, 2005)

    » The Ubiquitous Echo (November 7, 2005)

    » Zygote Media Group Releases New 3D Female Anatomy (November 4, 2005)

    » TempTouch® for Diabetics (October 31, 2005)

    » Pillow for Snorers (October 27, 2005)

    » Metabonomic Analysis Shows Feasibility in Meningitis Diagnosis (October 27, 2005)

    » Described: A New Technique for Obtaining Large-bore IV (October 25, 2005)

    » NIH Launches Program to Improve Clinical and Translational Science (October 13, 2005)

    » In the Works: A No-Prick Glucometer (October 12, 2005)

    » Genetically Manipulated Mosquito Species To Fight Malaria (October 11, 2005)

    » Gadgets All Look Alike (October 6, 2005)

    » Prototype SubQ Glucose Sensor to Be Featured at MoMA (September 29, 2005)

    » Afraid of Painful Vaccinations? Revolutionary Pain-Free Needles Revealed (September 29, 2005)

    » Mexico City's UNAM University Opened The World's Largest Robotic Training Center (September 27, 2005)

    » The VRIxp System: New Noninvasive Way to Image Lungs (September 15, 2005)

    » Reminder For HIV Patients (September 15, 2005)

    » Philips Launches A New Cardiology Ultrasound System (September 15, 2005)

    » "Smart" drug coatings (September 13, 2005)

    » RNAi (September 9, 2005)

    » Exubera Inhaled Insulin (September 8, 2005)

    » New Twinject Epinephrine Pen (August 31, 2005)

    » The MDKeeper™ (August 29, 2005)

    » ANSiscope (August 22, 2005)

    » The Breathscanner 1.0 (August 22, 2005)

    » MRI for Predicting Autoimmune Diabetes (August 22, 2005)

    » MD Turbo™ to Improve Inhaled Drug Delivery (August 17, 2005)

    » Guardian® RT Continuous Glucose Monitoring System (August 11, 2005)

    » Patient Bracelet Confirms Medications, Doses (August 11, 2005)

    » New DNA Tests on Tap to I.D. Bad Microbes (July 29, 2005)

    » 8T DAZE of Compliance (July 28, 2005)

    » Wrist Sensor by ETC (July 14, 2005)

    » Stabi-Line: No More Kinks (July 13, 2005)

    » The Accordion Pill (July 12, 2005)

    » Accu-Chek Multiclix Lancing Device (July 11, 2005)

    » Fingernail Test for Osteoporosis (July 11, 2005)

    » The Omnipod™ Integrated Insulin Delivery and Glucose Monitoring System (July 6, 2005)

    » The Transcend® Implantable Gastric Stimulator (IGS®) (July 5, 2005)

    » Technosphere® Insulin Enters into Phase 3 Safety Trial (June 30, 2005)

    » FerriScan™ (June 29, 2005)

    » A New Way to Get Refills (June 23, 2005)

    » Glucoband® (June 13, 2005)

    » Electroporation Therapy by Inovio (June 13, 2005)

    » Robot Food Inspector (June 9, 2005)

    » EECP Earns Disdain From MDs (June 2, 2005)

    » Vein Entry Indicator Device (VEID™) (May 23, 2005)

    » Babysim (May 20, 2005)

    » Sonic Flashlight™: Real Time Tomographic Reflection System (May 19, 2005)

    » Epi-Max for Diabetic Skin Ulcers (May 19, 2005)

    » Androscope i-stethos Advanced Electronic Stethoscope (May 18, 2005)

    » SIMpill Does USA (May 16, 2005)

    » VerifyNow™ Aspirin System (May 11, 2005)

    » RADAR System for Detecting New Drug Interactions (May 4, 2005)

    » Video of VeinViewer (April 29, 2005)

    » MedGem® Metabolism Measurer (April 27, 2005)

    » Sepet™: Blood Purification Filter for Liver Failure (April 25, 2005)

    » Inhaled insulin 'within a year' (April 21, 2005)

    » TempTouch for Foot Ulcer Detection (April 19, 2005)

    » Tape Measure for Assessing Early Diabetes (April 18, 2005)

    » ClearRx Pill Bottle (April 18, 2005)

    » GlucoWatch G2 Biographer (April 12, 2005)

    » SAGE Oxygen Therapeutic Device (April 6, 2005)

    » Novel Device for High Blood Pressure Implanted (April 1, 2005)

    » GlucoMON (March 30, 2005)

    » accuDEXA® (March 28, 2005)

    » S7 Elite CPAP System (March 25, 2005)

    » Symphony™ Diabetes Management System - Continuous Glucose Monitoring (March 25, 2005)

    » PDAnet Lab System (March 24, 2005)

    » 'Contact Lenses Report Glucose Levels' (March 24, 2005)

    » Glycosuria Checker WELL-U II (March 22, 2005)

    » Ritract Safety Products (March 18, 2005)

    » EpiFLO Transdermal Oxygen Delivery System (March 18, 2005)

    » Vitajet™ 3 (March 18, 2005)

    » RESPeRATE for HTN (March 18, 2005)

    » Inogen One Oxygen Therapy (March 16, 2005)

    » PHD Personal Hemodialysis System (March 16, 2005)

    » Rex-The Talking Bottle (March 10, 2005)

    » The HealthWear System for Weight Management (March 8, 2005)

    » NxStage System One Portable Dialysis (March 8, 2005)

    » PARI TREK ™ Compact Compressor (March 7, 2005)

    » VitalStim Therapy (March 3, 2005)

    » Japan Today: noninvasive glucometer, ultra thin needle, and more (March 2, 2005)

    » Handcranked fetal heart rate monitor, etc? (March 1, 2005)

    » Cell Phone Cameras as good as Direct Examination (February 23, 2005)

    » Avant® 4000 wireless pulse oximetry (February 21, 2005)

    » UltraStethoscope™ (February 21, 2005)

    » Glucone: noninvasive blood glucose (February 17, 2005)

    » C-Tools 2.0 (February 15, 2005)

    » Powerheart external defibrillators (February 14, 2005)

    » The GluMetrics technology (February 14, 2005)

    » Space-age medicine for earthly practices (February 11, 2005)

    » Coming up: Animas IR 1250 insulin pump (February 8, 2005)

    » Sleep apnea: new solutions by SleepUP (February 7, 2005)

    » Braun ThermoScan® Pro 4000 (February 3, 2005)

    » DexCom's Continuous Glucose Monitoring System (February 2, 2005)

    » Bioartificial kidney under study (February 1, 2005)

    » Reciprocating syringe from Avanda (January 27, 2005)

    » SIMpill (January 25, 2005)

    » Invacare HomeFill II system (January 24, 2005)

    » INR@Home (January 21, 2005)

    » MercuryNews.com on medical simulators (January 17, 2005)

    » CyberLogic: Confronting Osteoporosis (January 6, 2005)

    » Jonah from Mini Mitter (January 5, 2005)

    » FreeStyle Flash (January 3, 2005)

    » Visicu eICU (December 30, 2004)

    » PD ACCESS (December 30, 2004)

    » i-Stat (December 21, 2004)

    » SonoPrep (December 19, 2004)

    » BioZ Dx (December 15, 2004)

    » Endo-PAT2000 System (December 14, 2004)

    » T-Line Tensymeter (December 11, 2004)

    » Vein Contrast Enhancer (December 11, 2004)

    » EECP (December 11, 2004)

    » CardioMeter (December 10, 2004)